CAS No. 51-30-9

Batch: Purity:99.74
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Isoprenaline (Isoproterenol) HCl Chemical Structure
Chemical Structure
Check the Isoprenaline (Isoproterenol) HCl product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol;hydrochloride
CAS Number 51-30-9
Molecular Formula

C11H17NO3.HCl
Molecular Weight (MW) 247.72
SMILES CC(C)NCC(C1=CC(=C(C=C1)O)O)O.Cl
InChIKey IROWCYIEJAOFOW-UHFFFAOYSA-N

Biological Activity

Isoprenaline (Isoproterenol) HCl is a non-selective beta-adrenergic receptor agonist targeting beta-1 and beta-2 adrenergic receptors. Upon receptor binding, it activates the Gs protein-coupled signaling pathway, stimulating adenylate cyclase to elevate intracellular cyclic AMP (cAMP) levels. This downstream activation of protein kinase A (PKA) enhances cardiac chronotropic and inotropic functions, while simultaneously promoting smooth muscle relaxation in bronchial airways. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 50 mg/mL (201.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 50 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Reference

[1] Strosberg AD. Protein Sci. 1993;2(8):1198-209.

[2] Rockman HA, et al. Nature. 2002;415(6868):206-12.

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Note: Technical data last updated: Sep 1, 2026.