CAS No. 539-15-1
| CAS Number | 539-15-1 | |
|---|---|---|
| Molecular Formula |
C10H15NO |
|
| Molecular Weight (MW) | 165.23 | |
| SMILES | CN(C)CCC1=CC=C(C=C1)O |
Hordenine is a naturally occurring phenylethylamine alkaloid that functions as an adrenergic stimulant and a bacterial quorum-sensing inhibitor. It stimulates the release of norepinephrine in mammalian tissues and inhibits monoamine oxidase activity, thereby modulating adrenergic signaling. Furthermore, hordenine reduces bacterial biofilm formation and suppresses virulence factor production in pathogens such as Pseudomonas aeruginosa, exhibiting antibacterial potential. [1][2]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
33 mg/mL
(199.72 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 33 mg/mL |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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