CAS No. 9041-08-1

Batch: Purity:98.14
Heparin Sodium Chemical Structure
Chemical Structure
Check the Heparin Sodium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name sodium 6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
CAS Number 9041-08-1
Molecular Formula

(C12H16NS2Na3)20

SMILES CCC1CC(N[R])C(OC1CO[S]([O-])(=O)=O)OC2C(O)C(O)C(OC3C(CO[R])OC(OC4C(O)C(O[S]([O-])(=O)=O)C(OC5C(O)C(N[S]([O-])(=O)=O)C(C)OC5CO[S]([O-])(=O)=O)OC4C([O-])=O)C(N[S]([O-])(=O)=O)C3[S]([O-])(=O)=O)OC2C([O-]
InChIKey JRTRSJGZMRQDHI-UHFFFAOYSA-N

Ordering Information

Biological Activity

Heparin sodium is a sulfated glycosaminoglycan anticoagulant that directly targets antithrombin III (ATIII). By binding to ATIII, heparin markedly accelerates ATIII-mediated inactivation of key blood coagulation factors, specifically thrombin and factor Xa. This cascade inhibition prevents blood clot formation and extension, while also inhibiting the induction of cellular autophagy to regulate downstream cell signaling and survival mechanisms.

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 162 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Aliquotting Service

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Note: Technical data last updated: Sep 1, 2026.