Clinical Trials

Gabapentin hydrochloride is being evaluated across numerous clinical trials from Early Phase 1 through Phase 4, investigating a broad spectrum of conditions including postoperative pain, opioid dependence, uremic pruritus in chronic kidney disease, overactive bladder, herpetic neuralgia, and hot flashes in breast cancer patients. Sponsored by major academic medical centers and cooperative research groups—such as Stanford University, the University of Oklahoma, and the Alliance for Clinical Trials in Oncology—these studies encompass varied recruitment statuses, including completed, actively recruiting, and not yet recruiting trials.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07158476 RECRUITING
ACL Surgery; Pain Management
St. Louis University
 2025-10-21 PHASE4
NCT06992427 RECRUITING
Head and Neck Squamous Cell Carcinoma; Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8; Stage II Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8; Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8; Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Alliance for Clinical Trials in Oncology
 2025-06-05 PHASE3
NCT02219373 NOT_YET_RECRUITING
Pediatric Chronic Neuropathic Pain
Boston Children's Hospital
 2026-06 PHASE3
NCT05827159 RECRUITING
Alcohol Use Disorder
Yale University
 2024-08-17 PHASE3
NCT07308717 RECRUITING
Breast Cancer
Memorial Sloan Kettering Cancer Center
 2025-12-16 PHASE4
NCT07047040 NOT_YET_RECRUITING
Pain, Postoperative; Osteoarthritis, Knee
Assiut University
 2025-08-15 PHASE2; PHASE3
NCT04724252 RECRUITING
Pain, Postoperative
University of California, Davis
 2021-08-23 PHASE2; PHASE3
NCT04860141 RECRUITING
Dental Pain and Sensation Disorder; Pain, Postoperative
Loma Linda University
 2021-06-16 PHASE4
NCT07515456 RECRUITING
Theophylline; Sumatriptan; Gabapentin; Post-Dural Puncture Headache
Tanta University
 2024-12-01
NCT07777965 RECRUITING
Healthy Non-dependent, Recreational Sedative Users
Viatris Inc.
 2026-06-18 PHASE4
NCT07019103 ACTIVE_NOT_RECRUITING
Pain Management; Analgesia, Postoperative
Haroon Muhammad Khalil
 2025-03-02
NCT07429734 NOT_YET_RECRUITING
Overactive Bladder
Mansoura University
 2026-02 PHASE3
NCT05443555 ACTIVE_NOT_RECRUITING
HIV; Heavy Drinking
Boston Medical Center
 2023-11-20 PHASE2
NCT07750639 ENROLLING_BY_INVITATION
Opioid Abuse (Disorder); Opioid Analgesia; Opioid Analgesic Adverse Reaction; Opioid Consumption
AdventHealth
 2024-08-01 PHASE4
NCT06565546 ACTIVE_NOT_RECRUITING
Ventral Hernia
University of Florida
 2025-01-29
NCT05302999 RECRUITING
Spinal Cord Injuries
MetroHealth Medical Center
 2022-03-14 PHASE4
NCT07593313 RECRUITING
Central Post-Stroke Pain
Nanchong Central Hospital
 2024-01-01
NCT05064319 COMPLETED
Bipolar Disorder; Cannabis Use; Schizoaffective Disorder, Bipolar Type; Bipolar I Disorder; Bipolar II Disorder; Cannabis Use Disorder, Mild; Cannabis Use Disorder, Moderate; Cannabis Use Disorder, Severe
Medical University of South Carolina
 2022-02-24 PHASE2
NCT07169006 NOT_YET_RECRUITING
Bariatric Surgery Analgesia
Ain Shams University
 2026-01-01
NCT06997016 ENROLLING_BY_INVITATION
Postoperative Pain
Baylor Research Institute
 2025-05-05 PHASE4
NCT05664464 RECRUITING
Glioblastoma
University of Zurich
 2023-01-01 PHASE1; PHASE2
NCT07804784 COMPLETED
Breast Cancer Surgery Pain
Shaukat Khanum Memorial Cancer Hospital & Research Centre
 2026-01-01
NCT04619862 UNKNOWN
Pain; Neuropathic Pain; Irritability
University of British Columbia
 2021-05-15 PHASE2
NCT06379425 RECRUITING
Pain, Postoperative; Postoperative Pain, Acute
Northwell Health
 2024-03-01 PHASE4
NCT06887998 NOT_YET_RECRUITING
Emergence Agitation
Cairo University
 2025-03 PHASE3
NCT07131527 COMPLETED
Cholecystitis, Chronic
Sohag University
 2025-07-14
NCT07389551 COMPLETED
Orthopedic Surgery
Muhammad Aamir Latif
 2025-07-01
NCT05156060 RECRUITING
Head and Neck Cancer; Locally Advanced Head and Neck Carcinoma
Natalie Lockney
 2022-01-24 PHASE1; PHASE2
NCT05063656 COMPLETED
Autism Spectrum Disorder
David Cochran
 2022-02-04 PHASE4
NCT03498261 ACTIVE_NOT_RECRUITING
Pain, Postoperative; Opioid Use
Ohio State University
 2018-01-30 PHASE1
NCT07000201 NOT_YET_RECRUITING
Anxiety; Anxiety Disorder (Panic Disorder or GAD)
Cairo University
 2025-09-15
NCT04613024 WITHDRAWN
Weight Loss; Pain, Postoperative
Stanford University
 2025-07-01 EARLY_PHASE1
NCT05076110 COMPLETED
Hip Arthroscopy
Mayo Clinic
 2022-04-07 PHASE4
NCT06301061 UNKNOWN
Pain, Chronic; Lumbosacral Radiculopathy; Radicular; Neuropathic
Federico II University
 2024-04-01
NCT07349680 COMPLETED
Postherpetic Neuralgia
Assiut University
 2023-03-15 PHASE3
NCT06893172 NOT_YET_RECRUITING
Postherpetic Neuralgia ( PHN )
University of Medicine and Pharmacy at Ho Chi Minh City
 2025-04-01
NCT05921604 ACTIVE_NOT_RECRUITING
Post Operative Pain
Tanta University
 2023-06-30 PHASE3
NCT06776445 COMPLETED
Rosacea; Rosacea Subtype 1 (Erythematotelangiectatic)
First Affiliated Hospital of Chongqing Medical University
 2024-01-05 PHASE1
NCT06705101 NOT_YET_RECRUITING
Elective Surgical Patients; Blood Pressure
Liaquat National Hospital & Medical College
 2024-12-15 PHASE1; PHASE2
NCT06798662 NOT_YET_RECRUITING
Herpes Zoster (HZ)
Xiaguang Duan
 2025-02-01
NCT05965492 WITHDRAWN
Spinal Disorder
University of Miami
 2024-06-01 PHASE3
NCT06752486 RECRUITING
Pain After Photorefractive Keratectomy; VAS Will be Used to Assess Pain Postoperative
Research Institute of Ophthalmology, Egypt
 2024-12-01 PHASE1
NCT06254183 COMPLETED
Acute Kidney Injury; Obesity
Tanta University
 2024-12-01 PHASE4
NCT06781489 COMPLETED
Carpal Tunnel Syndrome
Universidad Europea de Madrid
 2025-02-19 PHASE4
NCT06778798 COMPLETED
Carpal Tunnel Syndrome
Universidad Europea de Madrid
 2025-02-19 PHASE4
NCT05620641 COMPLETED
Post Operative Nausea and Vomiting; Sleeve Gastrectomy; Morbid Obesity
Tanta University
 2022-10-01 PHASE3
NCT06212830 UNKNOWN
Provide Evidence-based Recommendations for Clinicians to Optimize Pain Control After CXL
Assaf-Harofeh Medical Center
 2024-02 EARLY_PHASE1
NCT07348952 COMPLETED
Transcutaneous Electrical Nerve Stimulation; Pudendal Neuralgia; Post Prostatectomy
Cairo University
 2023-09-01
NCT05690282 ACTIVE_NOT_RECRUITING
Post-operative Pain
University of California, San Diego
 2021-05-17 PHASE4
NCT05658887 COMPLETED
Pelvic Organ Prolapse; Perioperative/Postoperative Complications
Joseph Kowalski
 2023-01-01 PHASE4
NCT05658874 TERMINATED
Interstitial Cystitis; Levator Spasm; Bladder Pain Syndrome
Jocelyn Fitzgerald
 2022-12-06 PHASE3
NCT04865042 COMPLETED
Radiculopathy of Lumbosacral Spine Due to Disc Disorder
Lille Catholic University
 2022-02-02 PHASE4
NCT04429347 COMPLETED
Insomnia Due to Medical Condition; Chronic Pain
University of California, San Diego
 2020-07-29 PHASE2
NCT06466421 COMPLETED
Uremic Pruritus; Chronic Kidney Disease-associated Pruritus; Hemodialysis; End-stage Renal Disease; Renal Replacement Therapy; ESRD
Tanta University
 2024-07-01 PHASE4
NCT05510856 COMPLETED
Oncology
Tanta University
 2022-09-01 PHASE4
NCT04705480 COMPLETED
Analgesics; Gabapentin; Injuries; Narcotics; Pain; Trauma
CAMC Health System
 2021-04-12 PHASE4
NCT06091553 UNKNOWN
Neuropathy in Cacer Patien
Beni-Suef University
 2023-10-10 PHASE2
NCT06346522 COMPLETED
Catheter-related Bladder Discomfort (CRBD)
Ain Shams University
 2024-04-10 PHASE4
NCT05997355 UNKNOWN
Postoperative Pain; Opioid Use
University of Puerto Rico
 2023-09-01
NCT04144933 UNKNOWN
Anesthesia; General Anesthesia; Analgesics, Opioid; Opioid Free Anesthesia; Postoperative Ileus; Colorectal Surgery; Laparoscopic Surgery; Analgesia; Dexmedetomidine; Lidocaine; Ketamine
University of Saskatchewan
 2021-05-15 PHASE3
NCT03689114 COMPLETED
Epilepsies, Partial
Mario Negri Institute for Pharmacological Research
 2021-05-10 PHASE4
NCT05609682 COMPLETED
Post Operative Pain
University of Oklahoma
 2022-11-29 EARLY_PHASE1
NCT07625410 COMPLETED
Effectiveness of Drugs Was Compared for Treating Trigeminal Neuralgia; Pain; Pain Management
Rehman Medical Institute - RMI
 2023-05-01 PHASE2; PHASE3
NCT02633683 UNKNOWN
RLS
XenoPort, Inc.
 2016-01 PHASE4
NCT05820685 TERMINATED
Trauma Injury
The University of Texas Health Science Center, Houston
 2023-07-27 PHASE4
NCT05800847 UNKNOWN
Rotator Cuff Tears
Hughston Clinic
 2023-04 PHASE4
NCT07297888 COMPLETED
Pain
Shri Guru Ram Rai Institute of Medical and Health Sciences
 2022-07-20
NCT04855578 COMPLETED
Polypharmacy; Gabapentin; Pregabalin
McGill University Health Centre/Research Institute of the McGill University Health Centre
 2021-05-28
NCT05699876 UNKNOWN
Anxiety, Preoperarative
All India Institute of Medical Sciences
 2023-01-15
NCT05875610 UNKNOWN
Peripheral Neuropathy Due to Chemotherapy
Mit Ghamr Oncology Center
 2023-05-01 PHASE4
NCT05384210 UNKNOWN
Fibromyalgia
Mansoura University
 2022-06
NCT02560766 UNKNOWN
RLS
XenoPort, Inc.
 2016-02 PHASE4
NCT05427474 UNKNOWN
Traumatic Brain Injury
Zagazig University
 2022-12-01 PHASE3
NCT06112223 COMPLETED
Gabapentin; Tramadol; Postoperative Pain; Knee Arthroscopy; Spinal Anesthesia
Tanta University
 2023-04-01
NCT05184192 COMPLETED
COVID-19; Olfactory Disorder; Anosmia; Hyposmia; Parosmia
Washington University School of Medicine
 2022-01-10 PHASE2
NCT05494437 COMPLETED
Cannabis Withdrawal
PleoPharma, Inc.
 2022-10-27 PHASE2
NCT04631510 COMPLETED
Intensive Care Unit Sleep Disruption
Tufts Medical Center
 2020-12-01 EARLY_PHASE1
NCT06190132 COMPLETED
Uremic Pruritus in Hemodialysis Patients
Ain Shams University
 2023-04-01
NCT04613024 Not yet recruiting
Weight Loss|Pain Postoperative
Stanford University
 2023-07-01 Early Phase 1
NCT05494385 COMPLETED
Postoperative Pain
Indiana University
 2021-07-27 PHASE4
NCT05301205 UNKNOWN
Gabapentin
Cairo University
 2021-06-25 EARLY_PHASE1
NCT03859024 COMPLETED
Pain, Postoperative; Urethral Stricture
University of Alabama at Birmingham
 2019-03-22 PHASE4
NCT05626998 COMPLETED
Anesthesia
Ain Shams University
 2022-11-01 PHASE4
NCT06247488 COMPLETED
Abuse Potential
Arbor Pharmaceuticals, Inc.
 2022-01-31 PHASE4
NCT05659810 COMPLETED
Prolongation of Spinal Anesthesia
Ain Shams University
 2022-12-26 EARLY_PHASE1
NCT05392361 COMPLETED
Lumbar Spinal Stenosis With Nocturnal Calf Cramps
Yonsei University
 2022-06-09
NCT07267182 COMPLETED
Postoperative Pain
Muhammad Aamir Latif
 2022-08-01
NCT05276089 Not yet recruiting
Opioid Use
Dr Yu Fu|Teesside University|NIHR Applied Research Collaboration for North East and North Cumbria|North East Academic Health Science Network|Newcastle University
 2023-02-01 Not Applicable
NCT05100160 WITHDRAWN
Thoracic; Pulmonary Disease
M.D. Anderson Cancer Center
 2021-09-15 PHASE3
NCT05533684 COMPLETED
Pain, Postoperative
Minia University
 2022-09-01 EARLY_PHASE1
NCT02642484 UNKNOWN
Liver Cirrhosis
Tanta University
 2018-12 PHASE3
NCT04766229 COMPLETED
Menopause; Cancer; Insomnia
University College Dublin
 2021-06-21 PHASE2
NCT04230980 COMPLETED
Non-obstructive Azoospermia
Weill Medical College of Cornell University
 2020-07-28 PHASE3
NCT03220776 COMPLETED
Alcohol Use Disorder; Bipolar Disorder
Medical University of South Carolina
 2017-08-07 PHASE2
NCT04570436 COMPLETED
Abuse Potential
Viatris Specialty LLC
 2021-03-29 PHASE4
NCT03423264 WITHDRAWN
Oropharyngeal Cancer; HPV-Related Squamous Cell Carcinoma
University of Chicago
 2018-01-22 PHASE2
NCT05539924 UNKNOWN
Opioid Use
Research Institute of Ophthalmology, Egypt
 2022-09-15 PHASE3
NCT05609682 Recruiting
Post Operative Pain
University of Oklahoma
 2022-11-29 Early Phase 1
NCT05750875 COMPLETED
Pruritus; Uremia; Chronic Kidney Diseases
King Edward Medical University
 2022-05-01 PHASE4
NCT04939987 WITHDRAWN
Radical Prostatectomies
Wake Forest University Health Sciences
 2022-08 PHASE2; PHASE3
NCT03867240 WITHDRAWN
Pain, Postoperative; Scoliosis Idiopathic
Emory University
 2019-06 PHASE3
NCT03082755 RECRUITING
Alzheimer Disease
University of Texas at Austin
 2017-07-01 PHASE4
NCT03589898 COMPLETED
Autism Spectrum Disorder
University of Massachusetts, Worcester
 2017-09-14 EARLY_PHASE1
NCT05104424 UNKNOWN
Smell Dysfunction; Taste Disorders; Taste Disorder, Secondary, Sweet; Taste Disorder, Secondary, Bitter; Smell Disorder
Ministry of Health, Saudi Arabia
 2021-12-26 PHASE1
NCT03747562 WITHDRAWN
Head Neck Cancer; Radiation Neuropathy; Pain, Neuropathic
University Hospital, Ghent
 2019-03-01 PHASE3
NCT06097676 COMPLETED
Abuse Potential
Arbor Pharmaceuticals, Inc.
 2021-09-28 PHASE4
NCT05324761 COMPLETED
Failed Back Surgery Syndrome
Al-Kindy College of Medicine
 2022-04-25 PHASE4
NCT04818450 COMPLETED
Sleep Deprivation; Critically Ill
Mahidol University
 2021-04-19
NCT04429022 COMPLETED
Pain, Postoperative
State University of New York at Buffalo
 2020-11-24 PHASE3
NCT05750875 Completed
Pruritus|Uremia|Chronic Kidney Diseases
King Edward Medical University
 2022-05-01 Phase 4
NCT04802967 COMPLETED
No Condition
Dompé Farmaceutici S.p.A
 2021-02-08 PHASE1
NCT05172570 TERMINATED
Thoracotomy; Pain, Postoperative
Indiana University
 2021-04-06 PHASE3
NCT02685735 TERMINATED
Pain; Total Knee Replacement; Total Hip Replacement
Wake Forest University Health Sciences
 2016-06-02 PHASE4
NCT06354478 COMPLETED
Breast Cancer; Pain, Postoperative; Pain, Acute
National Cancer Institute, Egypt
 2021-01-01
NCT05413902 COMPLETED
Pain Management; Posterior Spinal Fusion
University of Puerto Rico
 2021-04-05 PHASE4
NCT05319756 COMPLETED
Abuse Potential
Viatris Specialty LLC
 2021-04-30 PHASE4
NCT03806530 COMPLETED
End Stage Renal Disease; Restless Legs Syndrome
Population Health Research Institute
 2019-05-01 PHASE3
NCT03151746 TERMINATED
Anesthesia; Urethral Obstruction
Northwestern University
 2018-01-14 PHASE4
NCT01678586 COMPLETED
Pain
Massachusetts General Hospital
 2012-12
NCT04976374 UNKNOWN
Analgesia
National Cancer Institute, Egypt
 2021-05-25
NCT04052139 COMPLETED
Chronic Pain; Alcohol Use, Unspecified; HIV Infections
Boston Medical Center
 2021-01-25 PHASE2
NCT05296759 COMPLETED
Diabetic Neuropathies
Alexandria University
 2021-02-01 PHASE4
NCT03346668 COMPLETED
Scarring Alopecia; Frontal Fibrosing Alopecia; Lichen Planopilaris; Central Centrifugal Cicatricial Alopecia; Central Centrifugal Scarring Alopecia
University of Minnesota
 2016-01-28 EARLY_PHASE1
NCT03351439 COMPLETED
Hip Pain Chronic
Western University, Canada
 2018-04-06
NCT05037994 COMPLETED
Pain, Shoulder
Zagazig University
 2021-04-01
NCT03205423 COMPLETED
Opioid-use Disorder; Alcohol Use Disorder
New York State Psychiatric Institute
 2017-08-01 PHASE2
NCT04176419 TERMINATED
Postoperative Pain Control; Opioid Consumption
Case Comprehensive Cancer Center
 2020-01-17 PHASE3
NCT04246697 COMPLETED
Head and Neck Cancer; Analgesia
University of Kansas Medical Center
 2019-11-01 PHASE4
NCT04658732 UNKNOWN
Sedation for Patients Undergoing Peribulbar Block
Ehab Tarek Fahmy
 2020-12-01 PHASE1
NCT02957097 WITHDRAWN
Pain, Postoperative; Acute Pain; Facial Pain
Massachusetts General Hospital
 2019-09 PHASE4
NCT02543944 COMPLETED
Drug Dependence
University of Arkansas
 2016-02 PHASE2; PHASE3
NCT05024825 TERMINATED
Pain, Postoperative
Albany Medical College
 2017-08-04 PHASE4
NCT04491786 COMPLETED
Spinal Fusion
Gia Dinh People Hospital
 2020-08-01
NCT03574792 COMPLETED
Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
Roswell Park Cancer Institute
 2018-05-03 PHASE2
NCT04805827 COMPLETED
Healthy
Pharma Guide CRO
 2021-02-25
NCT03012815 COMPLETED
Alcohol Withdrawal Syndrome
Mayo Clinic
 2017-02-01 PHASE4
NCT03084536 COMPLETED
Breast Cancer; Breast Cancer Female; Cancer of Breast
Washington University School of Medicine
 2017-06-07 PHASE2
NCT04700592 COMPLETED
Chronic Pain Following Surgical Procedure for Cancer
University Tunis El Manar
 2020-10-02
NCT04622618 COMPLETED
Nausea, Postoperative; Vomiting, Postoperative; Pain, Postoperative
Ain Shams University
 2020-09-15 EARLY_PHASE1
NCT03818919 COMPLETED
Rotator Cuff Tear
Henry Ford Health System
 2019-01-22 PHASE2
NCT03269344 COMPLETED
Oropharynx Cancer
Henry Ford Health System
 2017-06-05 PHASE3
NCT04620720 UNKNOWN
Post Operative Pain
Combined Military Hospital, Pakistan
 2020-08-01 EARLY_PHASE1
NCT03121963 WITHDRAWN
Pain Management
University of Alabama at Birmingham
 2017-11-10 PHASE4
NCT03335436 WITHDRAWN
Cesarean Delivery; Pain Management
Vanderbilt University Medical Center
 2018-04-01 PHASE4
NCT04148846 UNKNOWN
Headache, Post-Dural Puncture
University of Sao Paulo General Hospital
 2019-09-20
NCT04523935 COMPLETED
Cerebral Palsy; Excessive Crying; Pain
Sathbhavana Brain Clinic
 2005-12-07 PHASE4
NCT04285281 COMPLETED
Carpal Tunnel Syndrome
Universidad Europea de Madrid
 2020-04-01 PHASE4
NCT03123861 COMPLETED
Pelvic Organ Prolapse
University of North Carolina, Chapel Hill
 2017-06-01 PHASE4
NCT03472521 COMPLETED
Opioid Use; Postpartum Disorder; Chronic Pain Syndrome
Stanford University
 2018-09-17 PHASE4
NCT03820193 COMPLETED
Meniscus Disorder; Narcotic Use
Henry Ford Health System
 2019-01-22 EARLY_PHASE1
NCT03749642 COMPLETED
Painful Diabetic Neuropathy
Aziende Chimiche Riunite Angelini Francesco S.p.A
 2018-11-22 PHASE2
NCT07644065 COMPLETED
Impacted Third Molar; Postoperative Pain; Neuroinflammation; Anxiety
Plovdiv Medical University
 2019-09-30
NCT03120962 UNKNOWN
Herpes Zoster; Post-herpetic Neuralgia
Second Affiliated Hospital, Zhejiang University, School of Medicine
 2017-05
NCT03682367 TERMINATED
Cancer of Head and Neck; Narcotic Use
University of California, Davis
 2018-12-01 PHASE3
NCT02927405 WITHDRAWN
Postoperative Pain
State University of New York - Downstate Medical Center
 2020-03-04 PHASE4
NCT04256603 COMPLETED
Spinal Cord Injuries; Neuropathic Pain
MetroHealth Medical Center
 2019-08-01 PHASE4
NCT02595190 UNKNOWN
Pain
Southwest Hospital, China
 2015-03 PHASE4
NCT03750773 WITHDRAWN
Postoperative Pain
Indiana University
 2019-07-02 PHASE1; PHASE2
NCT04434430 COMPLETED
Non-obstetric Lower Abdominal Surgery
Indonesia University
 2019-11-11 PHASE1; PHASE2
NCT03255330 WITHDRAWN
Chronic Pain Due to Trauma; Spinal Cord Injuries
Masaryk University
 2017-10 PHASE3
NCT03825809 RECRUITING
Narcotic Use
Henry Ford Health System
 2019-01-22 PHASE2; PHASE3
NCT03818932 COMPLETED
Anterior Cruciate Ligament Injury
Henry Ford Health System
 2019-01-22 PHASE2; PHASE3
NCT04068506 COMPLETED
Hand Injuries
Dow University of Health Sciences
 2019-09-01 PHASE4
NCT03826615 COMPLETED
Hyperalgesia; Cataract Bilateral Nos
Seoul National University Hospital
 2019-02-01
NCT04653415 COMPLETED
Arthroplasty Complications; Knee Osteoarthritis; Pain, Postoperative; Perioperative Complication
Jagiellonian University
 2019-06-01 PHASE4
NCT03625011 RECRUITING
Tonsillitis; Tonsillectomy
Children's Healthcare of Atlanta
 2018-07-31 PHASE4
NCT03393702 COMPLETED
Pain, Postoperative; Surgery, Thoracic
National Institute for Tuberculosis and Lung Diseases, Poland
 2017-05-09 PHASE4
NCT02737826 COMPLETED
Chronic Pain; Opioid Pain Medication
Medical University of South Carolina
 2016-05
NCT02160301 WITHDRAWN
Post Operative Pain Control
University of North Carolina, Chapel Hill
 2017-11 PHASE4
NCT04025203 COMPLETED
Carpal Tunnel Syndrome
Francisco Unda Solano
 2019-08-01 PHASE4
NCT03708237 TERMINATED
Restless Legs Syndrome; End Stage Renal Disease
University of Alberta
 2019-02-19 PHASE2
NCT03275012 WITHDRAWN
Chronic Pain
Pharmaceutical Research Management srl
 2017-04-04 PHASE2
NCT03859102 UNKNOWN
Cardiac Surgery; Coronary Artery Disease; Aortic Valve Disease; Mitral Valve Disease; Tricuspid Valve Disease; Aortic Root Dilatation
James Cook University Hospital
 2018-12-17
NCT02163434 COMPLETED
Hyperemesis Gravidarum
State University of New York at Buffalo
 2014-06 PHASE2
NCT02987985 COMPLETED
Anesthesia; General Anesthesia; Analgesics, Opioid; Postoperative Complications; Pathologic Processes; Physiologic Effects of Drugs; Narcotics; Analgesics; Sleep Disordered Breathing; Obstructive Sleep Apnea of Child; Tonsillectomy; Respiratory Depression; Dexmedetomidine; Ketamine; Lidocaine; Gabapentin; Pulse Oximetry
University of Saskatchewan
 2017-10-15 PHASE3
NCT02480114 COMPLETED
Malignant Head and Neck Neoplasm; Mucositis; Radiation-Induced Disorder
Vanderbilt-Ingram Cancer Center
 2015-07 PHASE3
NCT03149432 COMPLETED
Amputation; Phantom Pain Following Amputation of Lower Limb
Centre d'Investigation Clinique et Technologique 805
 2017-02-22
NCT03619785 UNKNOWN
Rib Fractures; Rib Fracture Multiple
Andrew A Herring
 2018-11-06 PHASE4
NCT03679013 COMPLETED
Pain, Postoperative
Inova Health Care Services
 2019-04-19 PHASE2
NCT03472469 COMPLETED
Nonspecific Pain Post Traumatic Injury
The University of Texas Health Science Center, Houston
 2018-04-02 PHASE4
NCT03334721 COMPLETED
Bipolar I Disorder; Bipolar II Disorder; Cannabis Use Disorder; Substance Use Disorders
Medical University of South Carolina
 2017-10-01 PHASE2
NCT03496389 UNKNOWN
Muscle Weakness; Anterior Cruciate Ligament Rupture
Hospital Authority, Hong Kong
 2018-07-01 PHASE2; PHASE3
NCT03566394 UNKNOWN
Invasive Breast Cancer; Chemotherapeutic Toxicity; Myalgia; Arthralgia
British Columbia Cancer Agency
 2018-07-02 PHASE2; PHASE3
NCT02722603 TERMINATED
Chronic Pain
Pharmaceutical Research Management srl
 2018-09-12 PHASE3
NCT03158376 COMPLETED
Postoperative Pain; Chronic Pain
University Hospital, Lille
 2015-09 PHASE3
NCT03635905 COMPLETED
Pain
Medstar Health Research Institute
 2017-05-26 PHASE4
NCT02642315 COMPLETED
Restless Legs Syndrome
University of Missouri-Columbia
 2016-01
NCT03521167 UNKNOWN
Cardiac Surgery
Shanghai Zhongshan Hospital
 2018-05-01
NCT03334903 COMPLETED
Knee Osteoarthritis; Knee Pain Chronic; Opioid Use; Opioid Dependence
Brigham and Women's Hospital
 2018-05-15 PHASE4
NCT03540030 COMPLETED
Opioid Use; Shoulder Osteoarthritis; Avascular Necrosis; Rotator Cuff Tear; Arthritis;Inflammatory
OrthoCarolina Research Institute, Inc.
 2016-09 PHASE4
NCT03672162 COMPLETED
Total Abdominal Hysterectomy ,Pain , Acute Postoperative,Gabapentin , Celecoxib
Department of Medical Services Ministry of Public Health of Thailand
 2019-02-01
NCT02840240 COMPLETED
Pain
The Cleveland Clinic
 2016-01
NCT04003350 COMPLETED
Osteo Arthritis Knee
Rothman Institute Orthopaedics
 2017-12-21
NCT03080493 COMPLETED
Abortion, Induced; Cervical Preparation; Pain
University of California, Davis
 2017-03-20 PHASE4
NCT01776671 UNKNOWN
Pain; Quality of Life
Chicago Anesthesia Pain Specialists
 2013-02 PHASE3
NCT02856750 COMPLETED
Acute Pain
Denver Health and Hospital Authority
 2016-10 EARLY_PHASE1
NCT03758079 COMPLETED
Uremic Pruritus
University of Balamand
 2018-06-01 PHASE4
NCT02349477 COMPLETED
Alcohol Use Disorder; Alcohol Withdrawal
Medical University of South Carolina
 2014-11 PHASE2
NCT03681574 COMPLETED
Pain, Postoperative; Agitation States as Acute Reaction to Exceptional Stress; Anesthesia; Vomiting
Hospital Infantil Albert Sabin
 2017-07-01 PHASE4
NCT02944656 COMPLETED
Pain
Emory University
 2016-12-08 PHASE4
NCT03053427 COMPLETED
Restless Legs Syndrome (RLS)
Astellas Pharma Inc
 2017-03-30 PHASE4
NCT02531906 COMPLETED
Head and Neck Squamous Cell Carcinoma; Pain; Stomatitis
Roswell Park Cancer Institute
 2015-04-24 PHASE1
NCT02725710 COMPLETED
Other Abortion; Spontaneous Abortion
Duke University
 2016-08 PHASE2
NCT03088306 COMPLETED
Lumbar Spinal Stenosis; Lumbar Spinal Instability; Lumbar Spine Degeneration
Johns Hopkins University
 2017-07-01 EARLY_PHASE1
NCT03172234 COMPLETED
Effect of Laryngoscopy and Tracheal Intubation
Ghada Mohammed AboelFadl
 2017-06-15 PHASE2; PHASE3
NCT03047278 COMPLETED
Neuropathic Pain; Type 2 Diabetes Mellitus; Diabetic Neuropathy, Painful
Natalia Valadares de Moraes
 2015-11-01 PHASE4
NCT02771925 TERMINATED
Alcohol Dependence
Dayanand Medical College and Hospital
 2016-06 PHASE4
NCT01977937 COMPLETED
Pain, Postoperative
Oregon Health and Science University
 2013-11 PHASE4
NCT04292171 COMPLETED
Pain Control
University of Nevada, Las Vegas
 2017-05-01 EARLY_PHASE1
NCT02355886 COMPLETED
Bladder Carcinoma
University of Washington
 2015-04-22 PHASE2; PHASE3
NCT02977208 COMPLETED
Epilepsy; Chronic Pain
São Paulo State University
 2016-09 PHASE4
NCT01954927 COMPLETED
Sickle Cell Disease
St. Jude Children's Research Hospital
 2013-10-07 PHASE2
NCT01506453 COMPLETED
Acute Lymphoblastic Leukemia; Neuropathy; Neuropathic Pain
St. Jude Children's Research Hospital
 2012-01-24 PHASE2
NCT02987920 TERMINATED
Pain, Postoperative
University of Southern California
 2017-01 PHASE4
NCT02958566 UNKNOWN
Colon Cancer; Colon Diverticulosis; Colonic Neoplasms; Colonic Diverticulitis; Pain, Postoperative; Ileus; Ileus Paralytic; Ileus; Mechanical; Constipation Drug Induced; Constipation; Rectum Cancer; Rectum Neoplasm
University of Illinois College of Medicine at Peoria
 2017-01 PHASE4
NCT01868425 COMPLETED
Pain
University of Wisconsin, Madison
 2013-04 PHASE4
NCT03347916 UNKNOWN
Emergence Agitation After Desflurane Anesthesia
Kuwait Specialized Eye Center
 2017-01-05
NCT03186443 UNKNOWN
Herpetic Neuralgia
Second Affiliated Hospital of Guangzhou Medical University
 2017-10-01 PHASE3
NCT02155257 COMPLETED
Osteoarthritis
Wake Forest University Health Sciences
 2014-07 PHASE4
NCT03202459 UNKNOWN
Postoperative Complications; Postoperative Nausea and Vomiting
Faculdade de Ciências Médicas da Santa Casa de São Paulo
 2017-03-02
NCT02330094 COMPLETED
Aneurysmal Subarachnoid Hemorrhage
Mayo Clinic
 2014-12 PHASE4
NCT04345432 COMPLETED
Postural Orthostatic Tachycardia Syndrome
Medstar Health Research Institute
 2014-01
NCT02999724 UNKNOWN
Pelvic Organ Prolapse
Mount Sinai Hospital, Canada
 2017-01 PHASE3
NCT03241875 COMPLETED
Pain, Postoperative; Cholecystectomy, Laparoscopic
Faculty of Medicine, Sousse
 2016-12-01 PHASE4
NCT00885586 COMPLETED
Herpes Zoster; Postherpetic Neuralgia; Pain
Dominik Irnich
 2008-11 PHASE4
NCT02633657 WITHDRAWN
RLS
XenoPort, Inc.
 2016-01 PHASE1
NCT01675960 TERMINATED
Neurologically Impaired; Irritable Mood; Signs and Symptoms, Digestive; Sleeplessness; Chronic Pain
Gillette Children's Specialty Healthcare
 2012-04 PHASE2
NCT02703259 COMPLETED
Pain, Postoperative
Christiana Care Health Services
 2016-06 PHASE4
NCT02490345 COMPLETED
Drug Usage
Indiana University
 2015-10 PHASE1
NCT02374567 TERMINATED
Dementia; Depression; Schizophrenia; Psychosomatic Disorders; Anxiety Disorders
Hannover Medical School
 2015-01 PHASE3
NCT02926573 COMPLETED
Head and Neck Cancer; Acute Pain; Postoperative Pain
Washington University School of Medicine
 2016-06-24 PHASE4
NCT02605187 COMPLETED
Postoperative Pain
Stanford University
 2015-11
NCT02402543 COMPLETED
Hemorrhoids; Fissure in Ano; Rectal Fistula; Anal Condyloma
University of Vermont
 2014-06
NCT02252536 COMPLETED
Alcohol Use Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
 2015-06 PHASE2
NCT02076893 TERMINATED
Pain
Children's Hospitals and Clinics of Minnesota
 2014-03 PHASE4
NCT02944981 COMPLETED
Postoperative Nausea and Vomiting
Khon Kaen University
 2016-08 PHASE4
NCT02359110 COMPLETED
Postoperative Pain
Milton S. Hershey Medical Center
 2015-06 PHASE4
NCT03023501 COMPLETED
Postoperative Complications
King Saud University
 2014-03 PHASE2
NCT02918760 UNKNOWN
Pelvic Pain
Ain Shams University
 2016-03 PHASE3
NCT03850093 COMPLETED
Blood Pressure
Zagazig University
 2015-08 PHASE4
NCT02617121 UNKNOWN
Postoperative Nausea and Vomiting
Hallym University Medical Center
 2015-11
NCT02867176 COMPLETED
Pain
Instituto de Oftalmología Fundación Conde de Valenciana
 2016-01 PHASE4
NCT01067144 TERMINATED
Pain; Breast Cancer; Lung Cancer
Stanford University
 2010-05 PHASE3
NCT02557945 TERMINATED
Clinical High Risk for Psychosis
New York State Psychiatric Institute
 2015-08-01 PHASE1; PHASE2
NCT02117076 TERMINATED
Restless Leg Syndrome
Theresa Zesiewicz, MD
 2014-04 PHASE4
NCT02202707 WITHDRAWN
Vasomotor Symptoms; Cardiovascular Health
Beth Israel Deaconess Medical Center
 2014-05
NCT02424695 UNKNOWN
Restless Legs Syndrome
Cleveland Sleep Research Center
 2015-06 PHASE4
NCT00974376 COMPLETED
Cannabis Dependence; Cannabis Withdrawal; Cognitive Deficits
The Scripps Research Institute
 2009-11-04 PHASE2
NCT01893632 TERMINATED
Benzodiazepine Dependence
New York State Psychiatric Institute
 2013-07 PHASE2
NCT02351934 COMPLETED
Colorectal Disorders
Mayo Clinic
 2015-02 PHASE4
NCT02525848 COMPLETED
Postoperative Nausea and Vomiting
Assiut University
 2015-08 PHASE2; PHASE3
NCT02127853 UNKNOWN
Hyperalgesia
Seoul National University Hospital
 2014-07 PHASE4
NCT01680549 COMPLETED
Postoperative Pain
Texas Tech University Health Sciences Center
 2012-09 PHASE4
NCT01301001 COMPLETED
Vulvodynia
University of Tennessee
 2012-08
NCT02693821 COMPLETED
Pain, Postoperative
Hospital Italiano de Buenos Aires
 2015-12 PHASE4
NCT01546857 TERMINATED
Degenerative Arthritis and Postoperative Pain
Rutgers, The State University of New Jersey
 2012-03 PHASE4
NCT02339662 UNKNOWN
Myofacial Pain
Doron Aframian
 2015-02 PHASE4
NCT02466191 COMPLETED
Pendular Nystagmus; Oculopalatal Tremor
Hospices Civils de Lyon
 2015-06 PHASE4
NCT02306278 COMPLETED
Cerebral Tumor
Capital Medical University
 2014-12-14
NCT02252926 COMPLETED
Mucositis
Hvidovre University Hospital
 2014-09 PHASE2
NCT01707420 COMPLETED
Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
University of Colorado, Denver
 2012-08
NCT03179345 COMPLETED
Healthy
Depomed
 2015-09-24 PHASE4
NCT02599701 TERMINATED
Sleep
Associação Fundo de Incentivo à Pesquisa
 2015-09 PHASE4
NCT02419443 UNKNOWN
Peripheral Nerve Disorder Associated With Repair of Hernia
United States Naval Medical Center, San Diego
 2011-08 PHASE4
NCT02056899 COMPLETED
Preterm Labor, Premature Birth
State University of New York at Buffalo
 2013-06 PHASE1
NCT02040532 COMPLETED
Menopause; Hot Flashes; Vasomotor Disturbance
Massachusetts General Hospital
 2014-01
NCT02110719 COMPLETED
Narcotic Use; Pain; Constipation; Nausea
Hartford Hospital
 2014-03 PHASE4
NCT01112878 WITHDRAWN
Shoulder Arthroscopy; Knee Arthroscopy
Cedars-Sinai Medical Center
 2015-06 PHASE4
NCT02099006 COMPLETED
Female Genital Diseases
University of Rochester
 2013-11 PHASE2; PHASE3
NCT01981941 COMPLETED
Restless Legs Syndrome (RLS)
Astellas Pharma Inc
 2013-11-05 PHASE4
NCT02384187 COMPLETED
Post Operative Nausea and Vomiting (PONV); Adenotonsillectomy
Cairo University
 2015-01 PHASE3
NCT03005483 COMPLETED
Pain, Postoperative; Orthopedic Disorder
Hospital Infantil Albert Sabin
 2014-01 PHASE4
NCT03274167 COMPLETED
Alcohol Drinking; Heavy Drinking
Chulalongkorn University
 2012-01 PHASE3
NCT01486706 COMPLETED
Urinary Urgency; Urinary Frequency; Nocturia; Incontinence; Detrusor Uninhibited Activity; Quality of Life
Michael E. Chua
 2010-10 PHASE2; PHASE3
NCT01623271 TERMINATED
Complex Regional Pain Syndrome I (CRPS I)
Massachusetts General Hospital
 2013-05
NCT01588314 WITHDRAWN
Fabry Disease; Neuropathic Pain
University of Minnesota
 2012-04 PHASE2
NCT01495923 COMPLETED
Sciatica; Radiculopathy
Johns Hopkins University
 2011-12
NCT01441531 WITHDRAWN
Tourniquet-induced Pain; Tourniquet-induced Hypertension
Baylor College of Medicine
 2012-01 EARLY_PHASE1
NCT01489631 COMPLETED
Total Knee Arthroplasty
St. Antonius Hospital
 2013-03
NCT01005108 COMPLETED
Hot Flashes
Abramson Cancer Center at Penn Medicine
 2009-01 PHASE2
NCT00221338 COMPLETED
Postoperative Delirium; Postoperative Pain; Opioid Use; Hospital Length of Stay
University of California, San Francisco
 2006-01 PHASE3
NCT01533753 TERMINATED
Prostate Cancer
University of Wisconsin, Madison
 2012-02 PHASE2
NCT01888497 COMPLETED
Healthy
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2013-07-29 PHASE3
NCT01848119 COMPLETED
Pain
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2013-05
NCT01821235 COMPLETED
Epilepsy and Neuropathic Pain
University Hospital, Ghent
 2013-04 PHASE1
NCT01116583 COMPLETED
Pain, Postoperative
University of Aarhus
 2011-05 PHASE3
NCT02052414 COMPLETED
Fibromyalgia
The Center for Clinical Research, Winston-Salem, NC
 2012-07
NCT01144923 COMPLETED
Cervical Radiculopathy
Johns Hopkins University
 2010-06
NCT01507363 COMPLETED
Postoperative Pain; Postoperative Sedation
Hvidovre University Hospital
 2012-01 PHASE4
NCT01668667 COMPLETED
Restless Legs Syndrome
XenoPort, Inc.
 2012-06 PHASE4
NCT05436886 COMPLETED
Healthy Volunteers; Bioequivalence Study
University of Karachi
 2013-06-28
NCT00537940 COMPLETED
Epilepsy; Partial Seizure Disorder; Epilepsies, Partial; Complex Partial Seizure Disorder
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2008-02 PHASE4
NCT01744444 COMPLETED
Pendular Nystagmus Patients With Multiple Sclerosis
Hospices Civils de Lyon
 2012-11 PHASE2
NCT00619983 TERMINATED
Diabetic Neuropathic Pain; Chronic Low Back Pain
Wake Forest University
 2008-02 PHASE4
NCT01141049 COMPLETED
Alcohol Dependence
New York State Psychiatric Institute
 2010-08 PHASE2; PHASE3
NCT01421264 COMPLETED
Insomnia
State University of New York at Buffalo
 2011-08 PHASE1
NCT00954187 TERMINATED
Postoperative Pain
Loma Linda University
 2009-11
NCT01485185 COMPLETED
Pain, Neuropathic
GlaxoSmithKline
 2011-10-11 PHASE1
NCT01364298 COMPLETED
Diabetic Peripheral Neuropathic Pain
Merck KGaA, Darmstadt, Germany
 2011-04 PHASE4
NCT00480181 COMPLETED
Neuropathic Pain; Multiple Sclerosis
University of Manitoba
 2007-06 PHASE4
NCT01516372 COMPLETED
Restless Legs Syndrome
XenoPort, Inc.
 2012-01 PHASE1
NCT01262092 COMPLETED
Opioid Dependence; Opioid Withdrawal; Opioid Detoxification
University of Arkansas
 2010-10 PHASE2
NCT01143766 COMPLETED
Conscious Sedation
Indiana University
 2010-04
NCT01127100 COMPLETED
Neuropathic Pain; Spinal Stenosis
Seoul National University Hospital
 2010-05 PHASE4
NCT01411124 COMPLETED
Restless Legs Syndrome (RLS)
XenoPort, Inc.
 2011-06 PHASE1
NCT01476124 COMPLETED
Restless Legs Syndrome
XenoPort, Inc.
 2011-08 PHASE1
NCT02120703 COMPLETED
Intervertebral Disc Prolapse
Aga Khan University
 2011-02 PHASE3
NCT01014533 COMPLETED
Alcohol Dependence; Insomnia
Dr. Kirk Brower
 2007-05
NCT01080300 COMPLETED
Hot Flashes
Depomed
 2010-08 PHASE3
NCT01265056 COMPLETED
Pain; Burn Injury
Lucy A Wibbenmeyer
 2010-02
NCT01632215 COMPLETED
Carpal Tunnel Syndrome
Federal University of São Paulo
 2010-03 PHASE3
NCT01092520 WITHDRAWN
Pruritus
The Hospital for Sick Children
 2009-07 PHASE1
NCT02074267 COMPLETED
Neuropathy; Pain
Nang Kuang Pharmaceutical Co., Ltd.
 2009-03 PHASE4
NCT00934193 WITHDRAWN
Post-thoracotomy Pain
University of Kansas Medical Center
 2009-07 PHASE3
NCT00711529 COMPLETED
Breast Cancer; Hot Flashes
Women and Infants Hospital of Rhode Island
 2008-07 PHASE3
NCT00967707 COMPLETED
Post-traumatic Neuropathic Pain
Uppsala University
 2009-08 PHASE2
NCT01052896 WITHDRAWN
Functional Dyspepsia
59th Medical Wing
 2010-03 PHASE3
NCT00880191 COMPLETED
Nausea and Vomiting; Unspecified Adult Solid Tumor, Protocol Specific
Alliance for Clinical Trials in Oncology
 2009-04 PHASE3
NCT01307202 COMPLETED
Post Operative Pain; Total Knee Replacement
McMaster University
 2007-10
NCT00889148 COMPLETED
Postoperative Pain; Total Hip Replacement
McMaster University
 2007-10
NCT01738893 COMPLETED
Epilepsy
GlaxoSmithKline
 2011-01-14 PHASE1
NCT00420771 COMPLETED
Benzodiazepine Dependence; Opioid Dependence
New York State Psychiatric Institute
 2007-01 PHASE2
NCT00886236 COMPLETED
Obesity, Morbid; Postoperative Pain; Postoperative Nausea and Vomiting
Medical University of South Carolina
 2008-02
NCT01200641 COMPLETED
Anxiety; Pain
Qazvin University Of Medical Sciences
 2010-09 PHASE1; PHASE2
NCT01094925 COMPLETED
Pain
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2010-04
NCT00620555 COMPLETED
Epilepsies, Partial
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2008-05 PHASE3
NCT01177514 COMPLETED
Pain After Photorefractive Keratectomy
Codet Vision Institute
 2010-04 PHASE4
NCT01255878 COMPLETED
Sleep Bruxism
Mashhad University of Medical Sciences
 2010-03
NCT01236859 COMPLETED
Pruritus
Prince of Songkla University
 2009-09
NCT01573052 COMPLETED
Alcohol Withdrawal
VA Salt Lake City Health Care System
 2004-03 PHASE4
NCT01052844 COMPLETED
Vomiting; Cisplatin Adverse Reaction
Faculdade de Medicina do ABC
 2009-01 PHASE3
NCT00593463 COMPLETED
Drug Dependence
University of Arkansas
 2006-09 PHASE1
NCT00312260 COMPLETED
Pain
The Hospital for Sick Children
 2006-04 PHASE3
NCT00785772 TERMINATED
Renal Impairment
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2010-03 PHASE4
NCT01263132 COMPLETED
Diabetic Neuropathies; Polyneuropathies
Merck KGaA, Darmstadt, Germany
 2008-02 PHASE3
NCT01014520 UNKNOWN
Herniated Disc; Intervertebral Disc Displacement
Tabriz University
 2009-05 PHASE2
NCT00982800 COMPLETED
Prostate Cancer
Sunnybrook Health Sciences Centre
 2007-06 PHASE4
NCT00588159 COMPLETED
Pain
Michelle Kinney
 2007-06
NCT00603473 COMPLETED
Epilepsies, Partial
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2008-01 PHASE3
NCT01107574 COMPLETED
Fibromyalgia
Good Samaritan Regional Medical Center, Oregon
 2004-04 PHASE3
NCT00414466 TERMINATED
Chronic Intractable Pain
MedtronicNeuro
 2006-12 PHASE2
NCT00684112 COMPLETED
Scoliosis
The Hospital for Sick Children
 2008-05 PHASE3
NCT00987779 COMPLETED
Healthy
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2009-10 PHASE1
NCT00735124 TERMINATED
Pain; Analgesia; Hernia, Inguinal
University of Oklahoma
 2008-11-06 PHASE2; PHASE3
NCT01966172 COMPLETED
Analgesia; Postoperative Pain
Rigshospitalet, Denmark
 2007-03 PHASE4
NCT00755417 COMPLETED
Hot Flashes
Depomed
 2008-09 PHASE3
NCT00636636 COMPLETED
Neuralgia,Postherpetic
Depomed
 2008-03 PHASE3
NCT00385671 COMPLETED
Diabetic Neuropathy, Painful
Eli Lilly and Company
 2006-09 PHASE4
NCT00793910 COMPLETED
Postoperative Pain
Walter Reed Army Medical Center
 2008-07
NCT00617461 COMPLETED
Neuralgia, Postherpetic
XenoPort, Inc.
 2008-03 PHASE2
NCT00108550 COMPLETED
Chronic Low Back Pain
US Department of Veterans Affairs
 2004-10 PHASE2
NCT00391716 COMPLETED
Alcoholism; Alcohol Dependence
The Scripps Research Institute
 2004-02 PHASE2
NCT00777023 COMPLETED
Hot Flashes
Depomed
 2008-10 PHASE3
NCT00855738 COMPLETED
Focal Epilepsy
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2007-05 PHASE4
NCT00928954 COMPLETED
Nystagmus
Case Western Reserve University
 2005-02
NCT00654953 COMPLETED
Cocaine Dependence; Depressive Symptoms
University of Arkansas
 2006-01 PHASE2
NCT02658188 COMPLETED
Restless Legs Syndrome
Astellas Pharma Inc
 2007-12 PHASE3
NCT00572208 UNKNOWN
Pain, Postoperative
Aarhus University Hospital
 2008-01
NCT00578552 COMPLETED
Cigarette Smoking; Tobacco Use
Mayo Clinic
 2007-10 PHASE2
NCT00624455 COMPLETED
Post-operative Pain
University of British Columbia
 2007-07 PHASE3
NCT00183196 COMPLETED
Alcohol Dependence
Medical University of South Carolina
 2003-01 PHASE3
NCT00573664 TERMINATED
Pain
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2007-11
NCT01119222 COMPLETED
Healthy
Pfizer
 2008-07 PHASE1
NCT00634543 COMPLETED
Diabetic Neuropathy
Janssen Korea, Ltd., Korea
 2006-12 PHASE4
NCT00395044 COMPLETED
Cannabis Dependence
The Scripps Research Institute
 2006-08 PHASE2
NCT00726999 COMPLETED
Postoperative Pain
Medical College of Wisconsin
 2006-06
NCT00475904 COMPLETED
Post Herpetic Neuralgia; PHN; Neuropathy; Nerve Pain
EpiCept Corporation
 2007-07 PHASE2
NCT00800527 COMPLETED
Chest Pain; Paresthesia
Usak State Hospital
 2007-11 PHASE4
NCT00555776 UNKNOWN
Subjective Tinnitus
Islamic Azad University of Mashhad
 2007-01 PHASE2
NCT00236223 TERMINATED
Pain, Postoperative
Glostrup University Hospital, Copenhagen
 2005-10 PHASE4
NCT00390013 TERMINATED
Vulvar Pain Symptoms; Vulvodynia (Chronic Vulvar Pain)
Colleen Stockdale
 2007-01
NCT01210079 COMPLETED
Opioid-Induced Hyperalgesia
University of California, Los Angeles
 2002-09 PHASE2
NCT00262639 COMPLETED
Alcohol Dependence
Medical University of South Carolina
 2005-12 PHASE2; PHASE3
NCT00584779 TERMINATED
PK Properties Of Gabapentin In Subjects With Impaired Renal Function
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2007-10 PHASE4
NCT00511953 COMPLETED
Hot Flashes
Depomed
 2007-06 PHASE2
NCT00027963 COMPLETED
Neurotoxicity; Pain
Alliance for Clinical Trials in Oncology
 2002-02 PHASE3
NCT01250561 COMPLETED
Herpes Zoster; Post-herpetic Neuralgia
Center for Clinical Studies, Texas
 2002-02
NCT00250744 COMPLETED
Cancer
New Mexico Cancer Research Alliance
 2004-12 PHASE2
NCT01022736 COMPLETED
Cardiopulmonary Bypass
Queen's University
 2007-05 PHASE4
NCT00218374 COMPLETED
Hyperalgesia; Opioid-Related Disorders
National Institute on Drug Abuse (NIDA)
 2006-10
NCT00799149 COMPLETED
Knee Arthroscopy
Meir Medical Center
 2006-06 PHASE4
NCT00087399 COMPLETED
Breast Cancer; Hot Flashes
Alliance for Clinical Trials in Oncology
 2004-11 PHASE3
NCT00187707 COMPLETED
Healthy
University of California, San Francisco
 2005-09
NCT00028574 COMPLETED
Hot Flashes; Prostate Cancer
Alliance for Clinical Trials in Oncology
 2001-12 PHASE3
NCT01020162 COMPLETED
Chronic Pelvic Pain
Göteborg University
 1995-09
NCT00712439 COMPLETED
Diabetic Peripheral Neuropathy
Depomed
 2006-04 PHASE2
NCT00755508 COMPLETED
Sleep Initiation and Maintenance Disorders
Takeda
 2005-11 PHASE2
NCT00022074 COMPLETED
Anxiety Disorder; Breast Cancer; Depression; Hot Flashes
Gary Morrow
 2001-07
NCT00058890 COMPLETED
Liver Disease; Cholestasis; Cirrhosis; Pruritus; Itching
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
 2000-11 PHASE3
NCT00904202 COMPLETED
Postherpetic Neuralgia; Diabetic Neuropathy; Complex Regional Pain Syndrome; Carpal Tunnel Syndrome; HIV Neuropathy; Idiopathic Sensory Neuropathy; Peripheral Neuropathy
Endo USA Inc., a Keenova Therapeutics Company
 2003-01 PHASE4
NCT00778232 COMPLETED
Healthy
Ranbaxy Laboratories Limited
 2002-10
NCT00778401 COMPLETED
Healthy
Ranbaxy Laboratories Limited
 2002-10
NCT00778765 COMPLETED
Healthy
Ranbaxy Laboratories Limited
 2002-09
NCT00778271 COMPLETED
Healthy
Ranbaxy Laboratories Limited
 2002-09
NCT00865423 COMPLETED
Healthy
Actavis Inc.
 2001-02 PHASE1
NCT00865059 COMPLETED
Healthy
Actavis Inc.
 2001-02 PHASE1
NCT00865631 COMPLETED
Healthy
Actavis Inc.
 1999-06 PHASE1
NCT00864760 COMPLETED
Healthy
Actavis Inc.
 1999-06 PHASE1
NCT00015106 COMPLETED
Cocaine-Related Disorders
National Institute on Drug Abuse (NIDA)
 1997-11 PHASE2
NCT00864058 COMPLETED
Healthy
Actavis Inc.
 1998-01 PHASE1
NCT00864305 COMPLETED
Healthy
Actavis Inc.
 1997-12 PHASE1
NCT00018291 COMPLETED
Alzheimer's Disease; Dementia
US Department of Veterans Affairs
 2001-01
NCT00137735 COMPLETED
Carpal Tunnel Syndrome
Chinese University of Hong Kong
 2003-10 PHASE3
NCT00674752 COMPLETED
Transient Insomnia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2006-03 PHASE3
NCT00209872 UNKNOWN
Planned Abdominal Hysterectomy
Hvidovre University Hospital
 2005-10 PHASE4
NCT00189072 TERMINATED
Chronic Neuropathic Pain
UMC Utrecht
 2003-04 PHASE4
NCT00674687 COMPLETED
Neuralgia; Neuralgia, Postherpetic
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2004-07
NCT00169013 COMPLETED
Amputation of Lower Limb
Danish Pain Research Center
 2002-05 PHASE4
NCT00317850 TERMINATED
Tinnitus
Washington University School of Medicine
 2004-04 PHASE2; PHASE3
NCT00229125 COMPLETED
Alcohol Withdrawal Syndrome(AWS)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
 2001-07 PHASE2
NCT00159640 TERMINATED
Pain
Pfizer
 2004-02 PHASE2
NCT00577967 UNKNOWN
Pruritus; Uremia
Hospital Authority, Hong Kong
 2005-10
NCT01122004 UNKNOWN
Refractive Errors
Shahid Beheshti University of Medical Sciences
 PHASE1
NCT00257270 COMPLETED
Tinnitus
Tinnitus Research Consortium
 2003-08 PHASE2
NCT00276081 COMPLETED
Hot Flashes
University of Rochester
 2002-05 PHASE4
NCT00209885 UNKNOWN
Cholecystolithiasis
Hvidovre University Hospital
 2005-10 PHASE4
NCT00667108 COMPLETED
Transient Insomnia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2004-10 PHASE3
NCT00057278 COMPLETED
Fibromyalgia
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
 2003-03 PHASE2; PHASE3
NCT00666939 COMPLETED
Transient Insomnia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2004-10 PHASE3
NCT00644748 COMPLETED
Diabetic Neuropathies
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2003-05 PHASE4
NCT00112138 COMPLETED
Hot Flashes; Menopause
North Toronto Primary Care Research Network
 2004-03 PHASE3
NCT00533455 TERMINATED
Neuroleptic-Induced Tremor
Minneapolis Veterans Affairs Medical Center
 2004-03 PHASE3
NCT00666575 COMPLETED
Transient Insomnia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2004-12 PHASE3
NCT00153283 COMPLETED
Bronchial Asthma
Centre of Chinese Medicine, Georgia
 2003-09 PHASE4
NCT00001482 COMPLETED
Anxiety Disorder; Mood Disorder; Psychotic Disorder
National Institute of Mental Health (NIMH)
 1995-05 PHASE2
NCT00011297 COMPLETED
Alcoholism
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
 PHASE2
NCT00666796 COMPLETED
Insomnia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2005-04 PHASE4
NCT00163046 COMPLETED
Transient Insomnia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2005-10 PHASE3
NCT00279487 COMPLETED
Pain
Texas Health Resources
NCT00335933 COMPLETED
Neuralgia, Postherpetic
Depomed
 2006-05 PHASE3
NCT00007670 COMPLETED
Seizures
US Department of Veterans Affairs
 1998-01 PHASE3
NCT00666770 COMPLETED
Transient Insomnia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2004-10 PHASE3
NCT00143442 COMPLETED
Pain
Pfizer
 2003-12 PHASE2
NCT00659100 COMPLETED
Transient Insomnia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
 2006-08 PHASE3

(data from https://clinicaltrials.gov, updated on 2025-10-24)

Check the Gabapentin HCl product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Gabapentin hydrochloride acts as a structural GABA analogue that binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, thereby inhibiting presynaptic calcium influx and suppressing the release of excitatory neurotransmitters. This attenuation of central neuronal hyperexcitability and nociceptive signaling provides the physiological rationale for managing clinical trial conditions such as postoperative pain, neuropathic pain, and opioid withdrawal.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

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Note: Technical data last updated: Sep 1, 2026.