CAS No. 13189-98-5
Batch:
Purity:99.67
Chemical Structure
Check the
Fudosteine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 13189-98-5 | |
|---|---|---|
| Molecular Formula |
C6H13NO3S |
|
| Molecular Weight (MW) | 179.24 | |
| SMILES | C(CO)CSCC(C(=O)O)N |
Fudosteine is a cysteine derivative and a mucoactive agent that acts as a MUC5AC mucin hypersecretion inhibitor. It suppresses lipopolysaccharide- and TNF-alpha-induced MUC5AC gene expression and mucin synthesis in respiratory epithelial cells. These effects are mediated through the inhibition of ERK and p38 MAPK signaling pathways, thereby suppressing mucus hypersecretion in chronic respiratory disease models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 36 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
| Water | 36 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.