CAS No. 56296-78-7

Batch: Purity:99.04
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Fluoxetine Hydrochloride (LY-110140) Chemical Structure
Chemical Structure
Check the Fluoxetine Hydrochloride (LY-110140) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine;hydrochloride
CAS Number 56296-78-7
Molecular Formula

C17H18F3NO.HCl
Molecular Weight (MW) 345.79
SMILES CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl
InChIKey GIYXAJPCNFJEHY-UHFFFAOYSA-N

Ordering Information

Biological Activity

Fluoxetine Hydrochloride is a selective serotonin reuptake inhibitor (SSRI) that selectively targets the serotonin transporter at neuronal cell membranes. By inhibiting presynaptic serotonin reuptake, it effectively increases synaptic concentrations of 5-hydroxytryptamine and enhances downstream serotonergic neurotransmission. This sustained activation of central serotonergic signaling pathways alters neuronal plasticity, modulating neuroendocrine signaling and behavioral phenotypes associated with mood regulation. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 69 mg/mL (199.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 69 mg/mL
Ethanol 69 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.