Ezetimibe has been evaluated across numerous clinical trials spanning Phase 1 through Phase 4, alongside early phase studies, assessing its safety and low-density lipoprotein cholesterol-lowering efficacy as monotherapy or combined with statins and other lipid-lowering agents. These investigations focus on cardiovascular and metabolic disorders, including hypercholesterolemia, atherosclerosis, coronary artery disease, acute coronary syndrome, type 2 diabetes mellitus, and chronic kidney disease. Sponsored by pharmaceutical companies like Sanofi and Organon, alongside academic institutions including Korea University and Xijing Hospital, these trials encompass completed, active, recruiting, and terminated recruitment statuses.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT06722521 | RECRUITING | Primary Prevention; Vascular Calcification |
Asan Medical Center |
2025-07-09 | PHASE4 |
| NCT07524101 | RECRUITING | Renal Insufficiency; Atherosclerosis; Dyslipidemia; Hypercholesterolemia; Cardiovascular Diseases |
Yonsei University |
2026-05-28 | |
| NCT05579626 | ENROLLING_BY_INVITATION | Pre Diabetes; ASCVD |
Seung-Whan Lee, M.D., Ph.D. |
2023-03-14 | PHASE4 |
| NCT06649240 | RECRUITING | Ischemic Stroke; Small Vessel Cerebrovascular Disease; Cholesterol, LDL; Secondary Prevention; Cardiovascular Diseases |
Seoul National University Hospital |
2024-10-04 | |
| NCT07359105 | RECRUITING | Dyslipidemia Associated With Type II Diabetes Mellitus |
Sin Gon Kim |
2026-03-09 | |
| NCT07799779 | NOT_YET_RECRUITING | Acute Coronary Syndromes (ACS) |
Seoul National University Bundang Hospital |
2026-09 | PHASE4 |
| NCT06767774 | RECRUITING | ASCVD; Diabetes; Statin |
Korea University Anam Hospital |
2025-04-25 | PHASE4 |
| NCT07307989 | RECRUITING | Ischemic Stroke; Hypercholesteremia |
Chang Gung Memorial Hospital |
2025-08-01 | PHASE2 |
| NCT05845424 | RECRUITING | Coronary Artery Calcification; Metabolic Syndrome; Dyslipidemias |
Samsung Medical Center |
2023-07-03 | PHASE4 |
| NCT06186037 | RECRUITING | Coronary Artery Disease; Dyslipidemias; Primary Prevention |
Saint Vincent's Hospital, Korea |
2024-02-01 | PHASE4 |
| NCT07605130 | NOT_YET_RECRUITING | Intracranial Arteriosclerosis; Cognitive Impairment |
Peking Union Medical College Hospital |
2026-05-25 | PHASE4 |
| NCT07626840 | NOT_YET_RECRUITING | Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI) |
Samsung Medical Center |
2026-06-01 | |
| NCT07752758 | NOT_YET_RECRUITING | Atrial Fibrillation; Post-Catheter Ablation Atrial Arrhythmia Recurrence |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2026-08-15 | PHASE4 |
| NCT07474649 | NOT_YET_RECRUITING | Coronary Atherosclerosis; Mixed Dyslipidemia; Hypercholesterolemia |
Daiichi Sankyo |
2026-08-15 | PHASE3 |
| NCT07219602 | RECRUITING | Lipidemia; Type 2 Diabetes (T2DM); Metabolic Syndrome (MetS) |
NewAmsterdam Pharma |
2025-12-11 | PHASE3 |
| NCT06437574 | RECRUITING | Prostate Cancer |
Cedars-Sinai Medical Center |
2024-07-16 | PHASE2 |
| NCT06767345 | RECRUITING | Coronary Artery Disease; Atherosclerosis of Coronary Artery; Plaque, Atherosclerotic |
Korea University Anam Hospital |
2025-05-12 | PHASE4 |
| NCT04968509 | RECRUITING | Aortic Stenosis |
Beijing Anzhen Hospital |
2024-03-22 | PHASE3 |
| NCT05782777 | RECRUITING | Coronary Artery Disease Requiring Coronary Revascularization With Newer Generation DES Implantation |
Yonsei University |
2023-04-07 | |
| NCT07704918 | RECRUITING | Melanoma |
University of Colorado, Denver |
2026-12-31 | |
| NCT06305559 | ACTIVE_NOT_RECRUITING | Lipidemia; Coronary Artery Disease; Plaque, Atherosclerotic |
NewAmsterdam Pharma |
2024-05-16 | PHASE3 |
| NCT05641753 | RECRUITING | Type 1 Diabetes |
NYU Langone Health |
2022-12-06 | PHASE4 |
| NCT05705804 | RECRUITING | Dyslipidemias; Atherosclerotic Cardiovascular Disease |
Yonsei University |
2023-06-13 | |
| NCT06293417 | RECRUITING | T2DM (Type 2 Diabetes Mellitus); Dyslipidemias |
Korea University Anam Hospital |
2024-03-01 | |
| NCT03169985 | ACTIVE_NOT_RECRUITING | Coronary Artery Disease |
Samsung Medical Center |
2017-07-12 | PHASE4 |
| NCT05365438 | RECRUITING | Dyslipidemias; Atherosclerosis; Diabetes Mellitus, Type 2 |
Seoul National University Bundang Hospital |
2022-10-01 | PHASE4 |
| NCT06854523 | NOT_YET_RECRUITING | Acute Myocardial Infarction |
Yun Dai Chen |
2025-04-15 | |
| NCT07508254 | NOT_YET_RECRUITING | Acute Coronary Syndromes (ACS); Hypercholesterolemia |
Punjab Institute of Cardology |
2026-05-01 | PHASE4 |
| NCT05910476 | ACTIVE_NOT_RECRUITING | Coronary Artery Disease; Dyslipidemias |
Yonsei University |
2023-05-03 | PHASE4 |
| NCT07622433 | ACTIVE_NOT_RECRUITING | Healthy Participants |
AstraZeneca |
2026-06-10 | PHASE1 |
| NCT04499859 | RECRUITING | Myocardial Infarction; Statin Adverse Reaction; HMG-CoA Reductase Inhibitor Toxicity |
Kiyuk Chang, MD,PhD |
2020-10-01 | PHASE4 |
| NCT06317051 | ACTIVE_NOT_RECRUITING | HIV Infections; Weight Gain |
Kirby Institute |
2024-12-16 | PHASE3 |
| NCT06231966 | RECRUITING | Peripheral Artery Disease; Polyvascular Disease |
Yonsei University |
2024-04-22 | |
| NCT05587621 | NOT_YET_RECRUITING | ST Elevation Myocardial Infarction; Non-ST Elevation Myocardial Infarction; LDL-cholesterol |
Jena University Hospital |
2024-04-01 | |
| NCT07255820 | COMPLETED | Type 2 Diabetes Mellitus; Hypercholesterolemia / Elevated LDL Cholesterol |
Bahria University |
2026-01-01 | PHASE4 |
| NCT07268625 | COMPLETED | Healthy Subjects |
Daiichi Sankyo |
2025-12-09 | PHASE1 |
| NCT07235189 | COMPLETED | Healthy Subjects |
Daiichi Sankyo |
2025-10-28 | PHASE1 |
| NCT07442630 | ACTIVE_NOT_RECRUITING | Hypercholesterolemia |
JW Pharmaceutical |
2023-08-21 | PHASE4 |
| NCT07201545 | COMPLETED | Healthy Subjects |
Daiichi Sankyo |
2025-10-07 | PHASE1 |
| NCT04701242 | UNKNOWN | Acute Myocardial Infarction; Dyslipidemias |
Cairo University |
2021-03-24 | |
| NCT07182383 | COMPLETED | Healthy Subjects |
Daiichi Sankyo |
2025-09-29 | PHASE1 |
| NCT04508907 | ACTIVE_NOT_RECRUITING | Hepatitis C; Kidney Transplant; Complications; Heart Transplant Infection |
Mayo Clinic |
2020-09-10 | PHASE4 |
| NCT06742853 | COMPLETED | Dyslipidemia |
AstraZeneca |
2024-12-20 | PHASE1 |
| NCT06789432 | RECRUITING | Hyperlipidemia (E.G., Hypercholesterolemia) |
Dr. Md. Alimur Reza |
2025-02-01 | PHASE4 |
| NCT04626973 | COMPLETED | Atherosclerotic Cardiovascular Disease |
Yonsei University |
2021-01-15 | |
| NCT06784557 | RECRUITING | Atherosclerotic Cardiovascular Disease With Dyslipidemia |
Yonsei University |
2024-02-28 | PHASE4 |
| NCT06381947 | UNKNOWN | Dyslipidemias; Statin Adverse Reaction; Cardiovascular Diseases; Lipid Metabolism Disorders |
University of Salerno |
2024-05-01 | PHASE4 |
| NCT06646354 | ENROLLING_BY_INVITATION | Hypertension; Primary Hypercholesterolaemia |
Hyundai Pharm |
2025-04-22 | PHASE3 |
| NCT06450366 | COMPLETED | Hypercholesterolemia |
Merck Sharp & Dohme LLC |
2024-07-08 | PHASE3 |
| NCT05661552 | COMPLETED | Low-Density-Lipoprotein-Type [LDL] Hyperlipoproteinemia |
Yonsei University |
2022-12-01 | PHASE4 |
| NCT04862260 | ACTIVE_NOT_RECRUITING | Pancreatic Ductal Adenocarcinoma; Pancreatic Cancer; Pancreas Cancer; Metastatic Cancer |
CHU de Quebec-Universite Laval |
2021-10-04 | EARLY_PHASE1 |
| NCT05613400 | UNKNOWN | Diabetes Mellitus, Type 2 |
The University of Hong Kong |
2022-04-13 | PHASE4 |
| NCT06547359 | COMPLETED | Healthy Volunteers |
NewAmsterdam Pharma |
2024-10-01 | PHASE1 |
| NCT04900155 | UNKNOWN | STEMI; Covid19; NSTEMI |
Penza State University |
2020-11-20 | |
| NCT06005597 | COMPLETED | Dyslipidemias; Hypercholesterolemia; Familial Hypercholesterolemia; ASCVD; High Cholesterol |
NewAmsterdam Pharma |
2024-03-01 | PHASE3 |
| NCT05930028 | COMPLETED | Essential Hypertension; Primary Hypercholesterolemia |
Boryung Pharmaceutical Co., Ltd |
2023-07-13 | PHASE3 |
| NCT05761444 | COMPLETED | Atherosclerotic Cardiovascular Disease |
Organon and Co |
2023-07-26 | PHASE4 |
| NCT06578676 | UNKNOWN | Type 2 Diabetes; Dyslipidemias |
Hyundai Pharm |
2024-06-20 | PHASE1 |
| NCT05763875 | COMPLETED | Hypercholesterolemia |
Novartis Pharmaceuticals |
2023-03-15 | PHASE3 |
| NCT05368545 | COMPLETED | Coronary Artery Disease |
Aarhus University Hospital |
2020-05-15 | |
| NCT06050291 | COMPLETED | Healthy Volunteer Study |
NewAmsterdam Pharma |
2024-01-20 | PHASE1 |
| NCT06021951 | COMPLETED | Healthy Lactating Women |
Esperion Therapeutics, Inc. |
2023-08-04 | PHASE4 |
| NCT05795517 | COMPLETED | Hypercholesterolemia |
Haisco Pharmaceutical Group Co., Ltd. |
2023-04-26 | PHASE2 |
| NCT07564726 | COMPLETED | Hypertension; Hypercholesterolemia |
Celltrion Pharm, Inc. |
2022-08-05 | PHASE3 |
| NCT05884502 | UNKNOWN | Dyslipidemias; Stroke, Acute Ischemic |
Korea University Anam Hospital |
2022-09-01 | PHASE4 |
| NCT04369664 | COMPLETED | Type 2 Diabetes |
NYU Langone Health |
2020-08-12 | PHASE4 |
| NCT05263778 | UNKNOWN | Cardiovascular Diseases; NSTEMI; STEMI |
Kaiser Permanente |
2022-03 | PHASE4 |
| NCT04433533 | UNKNOWN | Left Ventricular Diastolic Dysfunction; Hyperlipidemias |
Yonsei University |
2021-01-06 | PHASE4 |
| NCT04826354 | COMPLETED | Atheroscleroses, Coronary |
Korea University Anam Hospital |
2021-08-11 | PHASE4 |
| NCT05970679 | COMPLETED | Hypercholesterolemia, Dyslipidemia |
Daewon Pharmaceutical Co., Ltd. |
2022-08-17 | PHASE3 |
| NCT04173403 | COMPLETED | Hypercholesterolemia |
Akeso |
2019-11-04 | PHASE2 |
| NCT04173793 | COMPLETED | Heterozygous Familial Hypercholesterolemia |
Akeso |
2019-11-18 | PHASE2 |
| NCT05381870 | UNKNOWN | Pharmacokinetics; Safety |
The Affiliated Hospital of Qingdao University |
2022-05-26 | PHASE1 |
| NCT05481385 | UNKNOWN | Pharmacokinetics; Safety |
The Affiliated Hospital of Qingdao University |
2022-07-15 | PHASE1 |
| NCT05266586 | COMPLETED | Dyslipidemias; High Cholesterol; Hypercholesterolemia |
NewAmsterdam Pharma |
2022-03-09 | PHASE2 |
| NCT04669041 | COMPLETED | Hypercholesterolemia |
Sanofi |
2020-12-08 | PHASE3 |
| NCT04659070 | UNKNOWN | Primary Hypercholesterolemia; Hypertension |
Hanlim Pharm. Co., Ltd. |
2020-07-15 | PHASE3 |
| NCT04589351 | UNKNOWN | Diabetes Mellitus, Type 2; Diabetic Kidney Disease |
Steno Diabetes Center Copenhagen |
2020-10-01 | PHASE3 |
| NCT03044665 | UNKNOWN | Cardiovascular Diseases; Cerebrovascular Disease; Peripheral Atherosclerotic Disease |
Yonsei University |
2017-03-15 | |
| NCT04659525 | UNKNOWN | Hypercholesterolemia; CKD Stage 5; Chronic Kidney Disease Requiring Chronic Dialysis |
Policlinico Casilino ASL RMB |
2020-11-01 | PHASE4 |
| NCT04161001 | UNKNOWN | Hypertension, Dyslipidemia |
Daewoong Pharmaceutical Co. LTD. |
2019-11-20 | PHASE3 |
| NCT03403556 | UNKNOWN | Atherosclerotic Cardiovascular Disease; Type 2 Diabetes |
Yuhan Corporation |
2018-03-27 | PHASE4 |
| NCT03993236 | COMPLETED | Stroke, Ischemic |
Keun-Sik Hong |
2019-09-09 | PHASE4 |
| NCT04643093 | COMPLETED | Primary Hypercholesterolemia; Mixed Dyslipidemias |
Orient Pharma Co., Ltd. |
2020-08-01 | PHASE3 |
| NCT04638400 | TERMINATED | Inflammation; Atherosclerosis; Hypercholesterolemia |
paresh Dandona |
2017-05-01 | PHASE4 |
| NCT04814589 | UNKNOWN | Therapeutic Equivalency |
Cao Yu |
2021-03-13 | PHASE1 |
| NCT04700436 | COMPLETED | Endocrine System Diseases; Nutritional and Metabolic Diseases; Diabetes Mellitus, Type 2; Dyslipidemias |
Seoul National University Hospital |
2020-01-03 | PHASE4 |
| NCT04770389 | COMPLETED | Dyslipidemias; High Cholesterol; Hypercholesterolemia |
NewAmsterdam Pharma |
2021-02-23 | PHASE2 |
| NCT02971033 | TERMINATED | Chronic Hepatitis C |
VA Office of Research and Development |
2018-04-16 | PHASE2 |
| NCT03768427 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2019-05-27 | PHASE3 |
| NCT03933293 | COMPLETED | Homozygous Familial Hypercholesterolemia |
Akeso |
2019-05-13 | PHASE2 |
| NCT04358432 | COMPLETED | Hypercholesterolemia |
Akeso |
2020-05-13 | PHASE2 |
| NCT03510884 | COMPLETED | Hypercholesterolaemia |
Sanofi |
2018-05-31 | PHASE3 |
| NCT04158076 | COMPLETED | Hypercholesterolemia; Hypertension |
Addpharma Inc. |
2020-01-23 | PHASE3 |
| NCT04017338 | UNKNOWN | Lung Transplant Infection; Heart Transplant Infection; Kidney Transplant Infection; Kidney Pancreas Infection; Hepatitis C |
Jordan Feld |
2018-08-06 | PHASE3 |
| NCT03847506 | COMPLETED | Hypertension, Hyperlipidemia |
HK inno.N Corporation |
2018-07-05 | PHASE4 |
| NCT03750760 | WITHDRAWN | Myocardial Infarction; Dyslipidemias |
Imperial College London |
2020-01 | PHASE4 |
| NCT04397653 | UNKNOWN | Hypercholesterolemia; Chronic Kidney Disease Requiring Chronic Dialysis |
Policlinico Casilino ASL RMB |
2020-05-04 | PHASE4 |
| NCT03872232 | COMPLETED | Hypercholesterolemia; Hypertension |
Addpharma Inc. |
2019-02-26 | PHASE3 |
| NCT03597412 | COMPLETED | Atherosclerotic Cardiovascular Disease; Type 2 Diabetes Mellitus |
Yuhan Corporation |
2018-10-17 | PHASE4 |
| NCT04584736 | COMPLETED | Primary Hypercholesterolemia |
JW Pharmaceutical |
2019-06-11 | PHASE3 |
| NCT04074551 | COMPLETED | Hypertension; Dyslipidemias |
Hanmi Pharmaceutical Company Limited |
2019-07-16 | PHASE3 |
| NCT03543774 | UNKNOWN | Hypercholesterolemia; Chronic Kidney Diseases |
Hue University of Medicine and Pharmacy |
2018-06-15 | PHASE4 |
| NCT03510715 | COMPLETED | Hypercholesterolemia |
Sanofi |
2018-08-31 | PHASE3 |
| NCT04844996 | COMPLETED | Endometriosis |
Mersin University |
2019-09-01 | EARLY_PHASE1 |
| NCT00679237 | COMPLETED | Coronary Heart Disease |
Sorlandet Hospital HF |
2007-09 | |
| NCT03355027 | UNKNOWN | Atherosclerosis; Cardiovascular Diseases |
Cambridge University Hospitals NHS Foundation Trust |
2017-11-30 | |
| NCT03494270 | COMPLETED | ASCVD |
Yuhan Corporation |
2018-03-18 | PHASE4 |
| NCT03434613 | COMPLETED | Nonalcoholic Fatty Liver Disease; Dyslipidemias |
Yonsei University |
2018-05-14 | PHASE4 |
| NCT04056169 | COMPLETED | Acute Coronary Syndrome; Carotid Atherosclerotic Plaque With Inflammation |
Yuhan Corporation |
2017-06-29 | PHASE4 |
| NCT03531905 | COMPLETED | Diabetes; Diabetes Mellitus, Type 2; Cholesterolemia |
Esperion Therapeutics, Inc. |
2018-05-09 | PHASE2 |
| NCT04080310 | COMPLETED | Cardiovascular Diseases |
Seoul National University Bundang Hospital |
2018-03-15 | PHASE4 |
| NCT02476006 | COMPLETED | Hypercholesterolemia |
Sanofi |
2015-06-23 | PHASE3 |
| NCT03217409 | COMPLETED | Diabetes Mellitus and Hypercholesterolemia |
Yuhan Corporation |
2017-08-10 | PHASE4 |
| NCT03771053 | UNKNOWN | Coronary Heart Disease |
Chinese PLA General Hospital |
2018-01-01 | |
| NCT03446261 | COMPLETED | Type 2 Diabetes Mellitus; Hypercholesterolemia |
Yuhan Corporation |
2018-02-23 | PHASE4 |
| NCT02534376 | COMPLETED | Prostate Cancer |
Cedars-Sinai Medical Center |
2015-09 | EARLY_PHASE1 |
| NCT02772640 | COMPLETED | Hypercholesterolemia |
Collegium Medicum w Bydgoszczy |
2016-03 | PHASE4 |
| NCT02890992 | COMPLETED | Hypercholesterolaemia |
Sanofi |
2016-09-15 | PHASE2 |
| NCT03532854 | COMPLETED | Healthy Male Volunteers |
LG Chem |
2018-05-28 | PHASE1 |
| NCT02715726 | COMPLETED | Hypercholesterolemia |
Sanofi |
2016-07-27 | PHASE3 |
| NCT02984982 | COMPLETED | Hypercholesterolemia; Acute Coronary Syndrome |
Sanofi |
2016-11-15 | PHASE4 |
| NCT03337308 | COMPLETED | Hyperlipidemias |
Esperion Therapeutics, Inc. |
2017-10-23 | PHASE3 |
| NCT05681247 | COMPLETED | Hyperlipidemias |
The Affiliated Hospital of Qingdao University |
2017-12-17 | PHASE1 |
| NCT04895059 | COMPLETED | Healthy |
Laboratorios Silanes S.A. de C.V. |
2017-04-30 | PHASE1 |
| NCT03001076 | COMPLETED | Hypercholesterolemia; Atherosclerosis; Statin Adverse Reaction |
Esperion Therapeutics, Inc. |
2016-11-29 | PHASE3 |
| NCT03277079 | UNKNOWN | Coronary Artery Disease |
University of Roma La Sapienza |
2017-10-01 | PHASE4 |
| NCT02748057 | COMPLETED | Hypercholesterolemia; Familial Hypercholesterolemia |
Organon and Co |
2016-05-18 | PHASE3 |
| NCT02588235 | UNKNOWN | Coronary Artery Disease |
Xijing Hospital |
2015-10 | PHASE4 |
| NCT02634580 | COMPLETED | Hypercholesterolemia |
Amgen |
2016-02-27 | PHASE3 |
| NCT03051100 | COMPLETED | Hypercholesterolemia |
Esperion Therapeutics, Inc. |
2017-01-19 | PHASE2 |
| NCT03099278 | UNKNOWN | Chronic Hepatitis D |
Ziauddin Hospital |
2017-01 | PHASE2 |
| NCT02682680 | COMPLETED | Type 2 Diabetes Mellitus |
LMC Diabetes & Endocrinology Ltd. |
2016-01-11 | PHASE4 |
| NCT02642159 | COMPLETED | Dyslipidemia |
Sanofi |
2016-03-15 | PHASE4 |
| NCT02749994 | COMPLETED | Hypercholesterolemia |
IlDong Pharmaceutical Co Ltd |
2016-04 | PHASE3 |
| NCT02741245 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2016-06-09 | PHASE3 |
| NCT02460159 | COMPLETED | Hypercholesterolemia; Heterozygous Familial Hypercholesterolemia |
Organon and Co |
2015-06-23 | PHASE3 |
| NCT03105310 | UNKNOWN | Hepatitis D, Chronic |
Aga Khan University |
2016-01 | PHASE2 |
| NCT02548936 | UNKNOWN | Atherosclerosis |
Peking Union Medical College Hospital |
2015-04 | EARLY_PHASE1 |
| NCT02550288 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2015-09-29 | PHASE3 |
| NCT02942602 | COMPLETED | Hyperlipidemia |
Yonsei University |
2014-04-03 | |
| NCT02768545 | UNKNOWN | Hepatitis C |
Pontificia Universidad Catolica de Chile |
2013-06 | PHASE4 |
| NCT02547402 | COMPLETED | Acute Kidney Injury |
Complexa, Inc. |
2015-12 | PHASE1 |
| NCT02126137 | UNKNOWN | Chronic Hepatitis C |
Pontificia Universidad Catolica de Chile |
2013-10 | PHASE1 |
| NCT01807078 | UNKNOWN | Coronary Artery Disease |
University of Roma La Sapienza |
2014-01 | PHASE4 |
| NCT02227784 | TERMINATED | Hyperlipidemia |
Eli Lilly and Company |
2014-10 | PHASE3 |
| NCT02501200 | COMPLETED | Healthy |
Chong Kun Dang Pharmaceutical |
2015-08 | PHASE1 |
| NCT03288038 | COMPLETED | Hypercholesterolemia |
Shin Poong Pharmaceutical Co. Ltd. |
2014-10-13 | PHASE3 |
| NCT01984424 | COMPLETED | Hyperlipidemia |
Amgen |
2013-12-10 | PHASE3 |
| NCT02103049 | COMPLETED | Dyslipidemia; Transplants |
University Medical Centre Ljubljana |
2014-04 | PHASE4 |
| NCT02260648 | TERMINATED | Hypercholesterolemia |
Eli Lilly and Company |
2015-01 | PHASE3 |
| NCT02461004 | COMPLETED | Healthy |
Chong Kun Dang Pharmaceutical |
2015-07 | PHASE1 |
| NCT02451098 | COMPLETED | Hyperlipidemia |
Chong Kun Dang Pharmaceutical |
2015-03 | PHASE3 |
| NCT01068093 | UNKNOWN | Coronary Artery Disease |
Yokohama City University Medical Center |
2010-10 | PHASE4 |
| NCT02244944 | TERMINATED | Nonalcoholic Fatty Liver Disease (NAFLD) |
Gregory Graf, PhD |
2014-09 | PHASE2 |
| NCT03571087 | COMPLETED | Primary Hypercholesterolemia |
Hanlim Pharm. Co., Ltd. |
2014-09 | PHASE3 |
| NCT02251847 | UNKNOWN | Hypercholesterolemia |
IlDong Pharmaceutical Co Ltd |
2014-07 | PHASE3 |
| NCT01603758 | COMPLETED | Coronary Heart Disease; Cardiovascular Disease; Dyslipidemia; Disorder of Cholesterol Metabolism |
Richard E. Ostlund Jr., MD |
2014-01 | PHASE1 |
| NCT01849068 | COMPLETED | Metabolic Syndrome X |
Laval University |
2013-06 | PHASE3 |
| NCT02234544 | COMPLETED | Vitamin D Deficiency |
Federal University of Rio Grande do Sul |
2014-10 | PHASE4 |
| NCT02288338 | COMPLETED | Healthy |
Chong Kun Dang Pharmaceutical |
2014-11 | PHASE1 |
| NCT02289430 | COMPLETED | Healthy |
NVP Healthcare |
2014-12 | PHASE1 |
| NCT02730689 | COMPLETED | Healthy Volunteers |
Alvogen Korea |
2014-12 | PHASE1 |
| NCT02445352 | COMPLETED | Primary Hypercholesterolemia |
Alvogen Korea |
2014-07 | PHASE3 |
| NCT02055976 | COMPLETED | Hypercholesterolemia |
Pfizer |
2014-03 | PHASE2 |
| NCT01520077 | COMPLETED | Alopecia Areata |
University of Miami |
2011-07 | PHASE1 |
| NCT00908011 | COMPLETED | Hypercholesterolemia; HIV Infections |
University of British Columbia |
2009-06 | |
| NCT01490229 | UNKNOWN | Coronary Artery Disease |
University of Roma La Sapienza |
2013-01 | PHASE4 |
| NCT01420549 | COMPLETED | Hypercholesterolemia; Dyslipidemia |
Ache Laboratorios Farmaceuticos S.A. |
2013-03 | PHASE3 |
| NCT01941836 | COMPLETED | Hypercholesterolemia |
Esperion Therapeutics, Inc. |
2013-09 | PHASE2 |
| NCT01950884 | UNKNOWN | •Non-alcoholic Steatohepatitis (NASH) |
University of Palermo |
2013-10 | PHASE4 |
| NCT00202878 | COMPLETED | Hypercholesterolemia; Myocardial Infarction |
Organon and Co |
2005-10-17 | PHASE3 |
| NCT02127320 | COMPLETED | Healthy |
Hanmi Pharmaceutical Company Limited |
2014-06 | PHASE1 |
| NCT01766713 | COMPLETED | Non Alcoholic Steatohepatitis |
University of California, San Diego |
2013-01 | PHASE2 |
| NCT01385631 | COMPLETED | ST-Segment Elevation Myocardial Infarction |
Odense University Hospital |
2011-06 | PHASE4 |
| NCT01709513 | COMPLETED | Hypercholesterolemia |
Regeneron Pharmaceuticals |
2012-09-30 | PHASE3 |
| NCT01587235 | WITHDRAWN | Dyslipidemia |
Organon and Co |
2013-03 | PHASE4 |
| NCT01644188 | COMPLETED | Hypercholesterolemia |
Sanofi |
2012-08 | PHASE3 |
| NCT01730053 | COMPLETED | Hypercholesterolemia |
Regeneron Pharmaceuticals |
2012-11-30 | PHASE3 |
| NCT01890967 | COMPLETED | Hypercholesterolemia |
Eli Lilly and Company |
2013-06 | PHASE2 |
| NCT01730040 | COMPLETED | Hypercholesterolemia |
Regeneron Pharmaceuticals |
2012-10 | PHASE3 |
| NCT01043380 | COMPLETED | Hypercholesterolemia; Coronary Artery Disease |
Kumamoto University |
2010-01 | PHASE4 |
| NCT02029625 | COMPLETED | Dyslipidemia |
NVP Healthcare |
2014-02 | PHASE1 |
| NCT01611883 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2012-07-02 | PHASE4 |
| NCT02129231 | COMPLETED | Oxidative Stress; Diabetic Polyneuropathy |
University of Guadalajara |
2012-02 | PHASE2 |
| NCT01763905 | COMPLETED | Hyperlipidemia |
Amgen |
2013-01-24 | PHASE3 |
| NCT01763866 | COMPLETED | Hyperlipidemia |
Amgen |
2013-01-15 | PHASE3 |
| NCT01857843 | COMPLETED | Acute Coronary Syndrome |
Yonsei University |
2009-11 | PHASE4 |
| NCT01516879 | COMPLETED | Hypercholesterolemia |
Amgen |
2012-01-05 | PHASE3 |
| NCT01763827 | COMPLETED | Hyperlipidemia |
Amgen |
2013-01-21 | PHASE3 |
| NCT01584206 | COMPLETED | Sitosterolemia |
University of Manitoba |
2012-04 | |
| NCT01644474 | COMPLETED | Hypercholesterolemia |
Sanofi |
2012-07 | PHASE3 |
| NCT00879710 | COMPLETED | Type 1 Diabetes Mellitus; Type 2 Diabetes Mellitus; Hypercholesterolemia |
Medical College of Wisconsin |
2008-08 | |
| NCT01723735 | COMPLETED | Hypercholesterolemia |
Sanofi |
2012-11 | PHASE1 |
| NCT00461630 | COMPLETED | Cardiovascular Disease; Peripheral Arterial Disease; Diabetes Mellitus; Coronary Heart Disease |
University of Oxford |
2007-01 | PHASE3 |
| NCT00926055 | WITHDRAWN | Atherosclerosis |
Korea University |
2011-09 | |
| NCT01154036 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2010-07 | PHASE3 |
| NCT01035320 | COMPLETED | Diabetes Mellitus; Impaired Renal Function |
Karolinska Institutet |
2006-01 | PHASE4 |
| NCT01375764 | COMPLETED | Hyperlipidemia |
Amgen |
2011-07-28 | PHASE2 |
| NCT01370603 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2011-09 | PHASE3 |
| NCT00867165 | COMPLETED | Primary Hypercholesterolemia |
Organon and Co |
2009-05-21 | PHASE3 |
| NCT01370590 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2011-09 | PHASE3 |
| NCT01375777 | COMPLETED | Hyperlipidemia |
Amgen |
2011-07-06 | PHASE2 |
| NCT02205775 | TERMINATED | Stable Coronary Artery Disease Undergoing PCI |
G. d'Annunzio University |
2010-05 | PHASE3 |
| NCT01597700 | COMPLETED | Hypercholesterolaemia |
GlaxoSmithKline |
2012-01-13 | PHASE1 |
| NCT02304926 | COMPLETED | Dyslipidemia |
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana |
2009-01 | |
| NCT00843661 | UNKNOWN | HIV; Hyperlipidemia; HIV Infections |
Ospedale di Circolo - Fondazione Macchi |
2009-03 | PHASE4 |
| NCT01086020 | UNKNOWN | Coronary Artery Disease |
Shanghai Jiao Tong University School of Medicine |
2010-01 | PHASE4 |
| NCT00819403 | COMPLETED | Metabolic Syndrome |
University of Maryland, Baltimore |
2009-01 | PHASE4 |
| NCT01236430 | COMPLETED | Hyperlipidemia |
Organon and Co |
2011-02 | PHASE1 |
| NCT00548145 | TERMINATED | Alzheimer Disease; Hypercholesterolemia |
Osaka University |
2007-11 | |
| NCT00965055 | TERMINATED | High Cholesterol; Coronary Artery Disease |
University of California, San Diego |
2009-09 | PHASE3 |
| NCT01185236 | UNKNOWN | Type 2 Diabetes Mellitus Without Insulin Treatment |
Seoul National University Hospital |
2010-09 | PHASE4 |
| NCT01218204 | COMPLETED | Dyslipidaemias; Dyslipidemias |
GlaxoSmithKline |
2010-09-14 | PHASE2 |
| NCT00955227 | COMPLETED | Hypercholesterolemia; Hyperlipidemia |
University of Manitoba |
2009-07 | |
| NCT00862251 | COMPLETED | Cardiovascular Disorder; Diabetes Mellitus |
Organon and Co |
2009-04 | PHASE3 |
| NCT01241097 | UNKNOWN | Endothelial Function |
Federal University of Bahia |
2010-03 | |
| NCT00972829 | UNKNOWN | Hypercholesterolemia |
Bronx VA Medical Center |
2009-09 | PHASE4 |
| NCT01112423 | COMPLETED | Dyslipidemia |
Bristol-Myers Squibb |
2010-06 | PHASE2 |
| NCT00687076 | COMPLETED | Peripheral Arterial Disease |
Baylor College of Medicine |
2004-04 | PHASE4 |
| NCT00817843 | COMPLETED | Metabolic Syndrome |
dr.Frank L.J. Visseren |
2009-04 | PHASE4 |
| NCT00738985 | WITHDRAWN | Cardiovascular Diseases; Hyperlipidemia |
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran |
2009-11 | PHASE4 |
| NCT00782184 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2008-11 | PHASE3 |
| NCT00477204 | COMPLETED | Type 1 Diabetes Mellitus; Dyslipidemia |
University of Colorado, Denver |
2007-05 | PHASE2 |
| NCT00125593 | COMPLETED | Kidney Disease, Chronic |
University of Oxford |
2003-06 | PHASE4 |
| NCT00738972 | TERMINATED | Hypertension |
Fundación Lindavista del Corazón AC |
2008-01 | PHASE3 |
| NCT00871351 | COMPLETED | Primary Hypercholesterolemia |
Organon and Co |
2009-02-01 | PHASE4 |
| NCT01384058 | COMPLETED | Diabetes Mellitus Type 2; Hypercholesterolemia |
University Hospital Freiburg |
2007-11 | PHASE4 |
| NCT00783263 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2008-11 | PHASE3 |
| NCT00932620 | COMPLETED | Hypercholesterolemia |
University of Ioannina |
2009-06 | PHASE4 |
| NCT00664469 | TERMINATED | Hypercholesterolemia |
Sunnybrook Health Sciences Centre |
2007-08 | PHASE3 |
| NCT00481351 | COMPLETED | Coronary Heart Disease |
University of Sao Paulo |
2007-06 | PHASE4 |
| NCT00905905 | COMPLETED | Myocardial Infarction |
Brasilia Heart Study Group |
2009-05 | PHASE4 |
| NCT00587678 | COMPLETED | Peripheral Artery Disease |
University of Virginia |
2006-01 | |
| NCT00863265 | COMPLETED | Hypercholesterolemia; Coronary Heart Disease |
Washington University School of Medicine |
2009-06 | EARLY_PHASE1 |
| NCT00699023 | COMPLETED | Postprandial Lipemia; Type 2 Diabetes |
Federico II University |
2008-06 | PHASE4 |
| NCT00397657 | TERMINATED | Atherosclerosis |
Walter Reed Army Medical Center |
2006-11 | PHASE4 |
| NCT00634140 | WITHDRAWN | Chronic Acalculous Cholecystitis |
Indiana University |
2009-08 | |
| NCT00654628 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2007-08-01 | PHASE4 |
| NCT00810303 | COMPLETED | Pharmacokinetics; Drug Interactions; Pharmacodynamics; Intestinal Transporter Expression |
University Medicine Greifswald |
2009-03 | PHASE1 |
| NCT00861731 | UNKNOWN | Hypercholesterolemia; Chronic Nephropathy |
Azienda Ospedaliero Universitaria di Sassari |
2008-11 | PHASE4 |
| NCT00653523 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2007-12-01 | PHASE3 |
| NCT00654095 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2007-12-01 | PHASE3 |
| NCT00725829 | UNKNOWN | Acute Coronary Syndrome |
Jagiellonian University |
2008-06 | |
| NCT01008345 | COMPLETED | Coronary Artery Disease; Diabetes |
Hotel Dieu de France Hospital |
2008-09 | PHASE4 |
| NCT00762164 | COMPLETED | Hypercholesterolemia |
Bronx VA Medical Center |
2007-03 | PHASE4 |
| NCT00701727 | COMPLETED | Hypercholesterolemia |
Radiant Research |
2008-06 | PHASE4 |
| NCT00485121 | COMPLETED | Metabolic Syndrome; Obesity; Coronary Artery Disease |
Canadian Collaborative Research Network |
2007-04 | |
| NCT00535405 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2007-11 | PHASE3 |
| NCT00474123 | COMPLETED | Stable Angina |
University of Sao Paulo |
2006-01 | |
| NCT00442897 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2006-09 | PHASE4 |
| NCT00559962 | COMPLETED | Hyperlipidemia |
Aegerion Pharmaceuticals, Inc. |
2007-10 | PHASE2 |
| NCT00639158 | COMPLETED | Dyslipidemias; Coronary Heart Disease; Combined (Atherogenic) Dyslipidemia; Mixed Dyslipidemia |
Abbott |
2008-02 | PHASE3 |
| NCT00418834 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2007-01 | PHASE3 |
| NCT00677248 | COMPLETED | Hypercholesterolemia |
Karo Bio AB |
2008-04 | PHASE2 |
| NCT00525824 | COMPLETED | Hypercholesterolemia; Coronary Heart Disease; Atherosclerosis |
AstraZeneca |
2007-08 | PHASE3 |
| NCT00762229 | COMPLETED | Hypercholesterolemia |
Bronx VA Medical Center |
2007-07 | |
| NCT00496730 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2007-07 | PHASE3 |
| NCT00772551 | COMPLETED | HIV |
St Stephens Aids Trust |
2008-06 | PHASE1 |
| NCT00409773 | COMPLETED | Hypercholesterolemia; Metabolic Syndrome |
Organon and Co |
2007-01 | PHASE3 |
| NCT00462748 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2007-03 | PHASE3 |
| NCT00681525 | COMPLETED | Pharmacokinetics |
Abbott |
2008-04 | PHASE1 |
| NCT00753883 | COMPLETED | Hyperlipidemia |
Merck Sharp & Dohme LLC |
2006-07 | PHASE4 |
| NCT00092677 | COMPLETED | Aortic Stenosis |
Organon and Co |
2001-01 | PHASE3 |
| NCT00376246 | COMPLETED | Endothelial Dysfunction |
University of California, San Diego |
2006-09 | PHASE4 |
| NCT00423579 | COMPLETED | Hypercholesterolemia; Coronary Disease |
Organon and Co |
2006-07-01 | PHASE4 |
| NCT00479713 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2007-02-01 | PHASE3 |
| NCT00988364 | COMPLETED | Metabolic Syndrome |
Baylor College of Medicine |
2007-03 | PHASE4 |
| NCT00276484 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2006-02 | PHASE3 |
| NCT00794677 | COMPLETED | Hypercholesterolemia |
UCSF Benioff Children's Hospital Oakland |
2006-06 | PHASE4 |
| NCT00271817 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2005-12 | PHASE3 |
| NCT00276458 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2006-02 | PHASE3 |
| NCT00203476 | COMPLETED | Hyperlipidemia; Hypercholesterolemia |
Tuscaloosa Research & Education Advancement Corporation |
2005-05 | PHASE4 |
| NCT00560170 | COMPLETED | Atherosclerosis |
National Cheng-Kung University Hospital |
2007-09 | PHASE4 |
| NCT00359281 | COMPLETED | Healthy |
Aegerion Pharmaceuticals, Inc. |
2006-03 | PHASE2 |
| NCT00621699 | COMPLETED | Pharmacokinetics; Drug Interactions; Hypercholesterolemia; Immunosuppression |
University Medicine Greifswald |
2007-09 | PHASE1 |
| NCT00166504 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2005-10 | PHASE4 |
| NCT00440154 | COMPLETED | Hypercholesterolemia |
Sanofi |
2007-02 | PHASE2 |
| NCT00157924 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2005-11 | PHASE4 |
| NCT00814723 | COMPLETED | Hypercholesterolemia |
Medical University of Graz |
2005-09 | PHASE4 |
| NCT02089867 | COMPLETED | Coronary Artery Disease |
Jose Rocha Faria Neto |
2006-10 | PHASE2; PHASE3 |
| NCT00652431 | COMPLETED | Hypercholesterolemia; Hyperlipidemia |
Organon and Co |
2007-05 | PHASE1 |
| NCT00652327 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2005-12 | PHASE4 |
| NCT00132717 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2005-01-01 | PHASE3 |
| NCT00129402 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2005-08 | PHASE3 |
| NCT00621101 | COMPLETED | Pharmacokinetics; Drug Interactions; Hypercholesterolemia; Immunosuppression |
University Medicine Greifswald |
2007-04 | PHASE1 |
| NCT00395603 | TERMINATED | Cardiovascular Diseases; Diabetes Mellitus |
Organon and Co |
2006-09 | PHASE3 |
| NCT00652847 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2005-05 | PHASE4 |
| NCT00385658 | COMPLETED | Dyslipidemia |
Novartis |
2006-08 | PHASE4 |
| NCT00423488 | COMPLETED | Hypercholesterolemia; Diabetes Mellitus, Type 2; Coronary Disease |
Organon and Co |
2005-07-12 | PHASE3 |
| NCT00166530 | COMPLETED | Atherosclerosis |
Organon and Co |
2005-11 | PHASE4 |
| NCT00405067 | COMPLETED | Hypercholesterolemia |
Aegerion Pharmaceuticals, Inc. |
2006-05 | PHASE2 |
| NCT00268697 | COMPLETED | Hypercholesterolemia |
Takeda |
2005-10 | PHASE3 |
| NCT00413972 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2006-04 | PHASE3 |
| NCT00101439 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2005-11-10 | PHASE3 |
| NCT00319449 | COMPLETED | Hypercholesterolemia; Coronary Arteriosclerosis |
Organon and Co |
2005-09 | PHASE4 |
| NCT00202904 | COMPLETED | Hypercholesterolemia; Coronary Heart Disease |
Organon and Co |
2005-05 | PHASE4 |
| NCT01424891 | COMPLETED | Type 2 Diabetes; Inflammation |
Heidelberg University |
2004-04 | |
| NCT00651014 | TERMINATED | Hypercholesterolemia; Atherosclerosis |
Organon and Co |
2004-01 | PHASE4 |
| NCT01103648 | COMPLETED | Prediabetes; Hypercholesterolemia; Inflammation; Cardiovascular Risk |
Federal University of São Paulo |
2005-06 | |
| NCT00552097 | COMPLETED | Atherosclerosis; Hypercholesterolemia; Hyperlipoproteinemia Type II |
Organon and Co |
2002-06-01 | PHASE3 |
| NCT00328523 | COMPLETED | Hypercholesterolaemia; Hyperlipidaemia |
Organon and Co |
2004-06 | PHASE3 |
| NCT00651560 | COMPLETED | Hyperlipidemia |
Organon and Co |
2005-11-01 | PHASE3 |
| NCT00110435 | COMPLETED | Type 2 Diabetes Mellitus; Hypercholesterolemia |
Organon and Co |
2005-05 | PHASE3 |
| NCT00738296 | COMPLETED | Cardiovascular Diseases |
Hospital Universitario 12 de Octubre |
2005-04 | PHASE4 |
| NCT00395473 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2005-03 | PHASE3 |
| NCT00457275 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2005-04 | PHASE3 |
| NCT00541697 | COMPLETED | Diabetes Mellitus, Type 2 |
Organon and Co |
2005-01-19 | PHASE3 |
| NCT00092898 | COMPLETED | Lipid Metabolism, Inborn Errors; Heart Disease |
Organon and Co |
2004-10 | PHASE3 |
| NCT00093899 | COMPLETED | Hyperlipidemia; Hypercholesterolemia; Hypertriglyceridemia |
Organon and Co |
2004-11 | PHASE3 |
| NCT00171288 | COMPLETED | Dyslipidemia |
Novartis |
2003-08 | PHASE3 |
| NCT00651378 | TERMINATED | Hypercholesterolemia; Atherosclerosis; Coronary Artery Disease |
Organon and Co |
2004-09-01 | PHASE4 |
| NCT00092833 | TERMINATED | Hypercholesterolemia, Familial; Lipid Metabolism, Inborn Errors |
Organon and Co |
2002-07 | PHASE3 |
| NCT00651963 | COMPLETED | Lipid Metabolism Disorder |
Organon and Co |
2004-09 | PHASE4 |
| NCT00652717 | COMPLETED | Cardiovascular Disorder |
Organon and Co |
2005-02-01 | PHASE4 |
| NCT00650819 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2004-06-01 | PHASE3 |
| NCT00650689 | COMPLETED | Hypercholesterolemia; Atherosclerosis; Coronary Artery Disease |
Organon and Co |
2003-05 | PHASE3 |
| NCT00090298 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2004-04 | PHASE3 |
| NCT00651404 | COMPLETED | Hypercholesterolemia; Atherosclerosis |
Organon and Co |
2004-01 | PHASE3 |
| NCT00092573 | COMPLETED | Hypercholesterolemia; Hypertriglyceridemia |
Organon and Co |
2003-04 | PHASE3 |
| NCT00090168 | COMPLETED | Hypercholesterolemia; Atherosclerotic Disease; Coronary Disease |
Organon and Co |
2004-01-27 | PHASE3 |
| NCT00650663 | COMPLETED | Hypercholesterolemia; Atherosclerosis |
Organon and Co |
2003-10-01 | PHASE4 |
| NCT00651391 | TERMINATED | Hypercholesterolemia; Atherosclerosis |
Organon and Co |
2003-10-01 | PHASE3 |
| NCT00653913 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2004-03 | PHASE1 |
| NCT00653835 | COMPLETED | Hypercholesterolaemia; Atherosclerosis |
Organon and Co |
2003-09-01 | PHASE4 |
| NCT00653796 | COMPLETED | Hypercholesterolemia; Atherosclerosis |
Organon and Co |
2003-09-01 | PHASE4 |
| NCT00651274 | COMPLETED | Atherosclerosis; Hypercholesterolemia; Coronary Heart Disease |
Organon and Co |
2003-04-01 | PHASE4 |
| NCT00652444 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2003-09 | PHASE4 |
| NCT00092625 | COMPLETED | Hypercholesterolemia; Coronary Disease |
Organon and Co |
2003-03 | PHASE3 |
| NCT00092638 | COMPLETED | Hypercholesterolemia; Coronary Disease |
Organon and Co |
2003-05 | PHASE3 |
| NCT00317993 | COMPLETED | Healthy Men |
University of Cologne |
2004-04 | PHASE4 |
| NCT00092599 | COMPLETED | Hypercholesterolemia; Coronary Disease |
Organon and Co |
2003-02 | PHASE3 |
| NCT00092612 | COMPLETED | Hypercholesterolemia; Coronary Disease |
Organon and Co |
2003-05 | PHASE3 |
| NCT00652301 | COMPLETED | Cholesterol |
Organon and Co |
2003-07 | PHASE3 |
| NCT00092690 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2003-06 | PHASE3 |
| NCT00653276 | COMPLETED | Cholesterol |
Organon and Co |
2003-11 | PHASE1 |
| NCT00092560 | COMPLETED | Hypercholesterolemia; Hypertriglyceridemia |
Organon and Co |
2002-12 | PHASE3 |
| NCT00092586 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2002-09 | PHASE3 |
| NCT00157911 | COMPLETED | Hypercholerolemia |
Organon and Co |
2002-12 | PHASE3 |
| NCT00092664 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2003-01 | PHASE3 |
| NCT03885921 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2000-10-25 | PHASE3 |
| NCT00092651 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2002-09 | PHASE3 |
| NCT00651144 | COMPLETED | Hypercholesterolemia; Atherosclerosis |
Organon and Co |
2003-03 | PHASE1 |
| NCT00092716 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2002-05 | PHASE3 |
| NCT00551447 | COMPLETED | Coronary Disease |
Organon and Co |
2002-01 | PHASE3 |
| NCT03882996 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2000-10-06 | PHASE3 |
| NCT00551876 | COMPLETED | Diabetes Mellitus, Type 2 |
Organon and Co |
2001-12 | PHASE3 |
| NCT03882892 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2001-02-02 | PHASE3 |
| NCT03867318 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2000-04-24 | PHASE3 |
| NCT00092820 | COMPLETED | Lipid Metabolism, Inborn Errors; Heart Disease |
Organon and Co |
2001-02-12 | PHASE3 |
| NCT00092807 | COMPLETED | Lipid Metabolism, Inborn Errors; Heart Disease |
Organon and Co |
2001-02-12 | PHASE3 |
| NCT03867110 | COMPLETED | Hypercholesterolemia |
Organon and Co |
2000-03-06 | PHASE3 |
| NCT03882905 | COMPLETED | Primary Hypercholesterolemia |
Organon and Co |
2001-01-31 | PHASE3 |
| NCT03884452 | COMPLETED | Familial Hypercholesterolemia |
Organon and Co |
2000-05-03 | PHASE3 |
| NCT00099684 | COMPLETED | HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
2005-11 | |
| NCT00099996 | COMPLETED | Heart Diseases; Metabolism, Inborn Errors |
National Heart, Lung, and Blood Institute (NHLBI) |
2004-12 | PHASE3 |
| NCT00189085 | COMPLETED | Metabolic Syndrome |
UMC Utrecht |
2004-12 | PHASE4 |
| NCT00433823 | UNKNOWN | Coronary Heart Disease; Diabetes Mellitus; Non-Coronary Atherosclerotic Disease; Hypercholesterolemia |
Abant Izzet Baysal University |
2007-01 | PHASE4 |
| NCT00195793 | COMPLETED | Hyperlipidemia |
Abbott |
2004-08 | PHASE3 |
| NCT00449410 | COMPLETED | Atrial Fibrillation; Neuropsychology; Magnetic Resonance Imaging; Inflammation; Hemostasis |
Radboud University Medical Center |
2005-05 | PHASE4 |
| NCT00475826 | UNKNOWN | Heterozigous Familial Hypercholesterolemia |
University of Sao Paulo |
2007-04 | |
| NCT00157482 | COMPLETED | Type 2 Diabetes |
Mario Negri Institute for Pharmacological Research |
2005-01 | PHASE2 |
| NCT00566267 | COMPLETED | Hyperlipidemia |
Merck Sharp & Dohme LLC |
2006-04 | PHASE2; PHASE3 |
| NCT00461968 | COMPLETED | Cholesterol, LDL |
University of Texas Southwestern Medical Center |
2005-02 | |
| NCT00045812 | COMPLETED | Lipoidosis |
National Heart, Lung, and Blood Institute (NHLBI) |
2001-03 | PHASE2 |
| NCT00349284 | COMPLETED | Hyperlipidemia Combined |
Solvay Pharmaceuticals |
2005-01 | PHASE3 |
| NCT00079638 | COMPLETED | Dyslipidemia; Coronary Heart Disease; Atherosclerosis; Stroke; Diabetes |
Kos Pharmaceuticals |
2004-04 | PHASE4 |
| NCT00267267 | TERMINATED | Hyperlipidemia; Dyslipidemia |
Pfizer |
2006-01 | PHASE3 |
| NCT00653445 | COMPLETED | Hypercholesterolemia; Coronary Heart Disease; Atherosclerosis |
AstraZeneca |
2004-06 | PHASE3 |
| NCT00185107 | COMPLETED | Hypercholesterolemia |
Daiichi Sankyo |
2005-03 | PHASE4 |
| NCT00466401 | COMPLETED | Hypercholesterolemia |
Ziv Hospital |
2005-02 | PHASE4 |
(data from https://clinicaltrials.gov, updated on 2025-08-07)
Check the
Ezetimibe (SCH-58235)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
- Ezetimibe (SCH-58235) Solubility in DMSO
- Ezetimibe (SCH-58235) Stock Solution
- Ezetimibe (SCH-58235) Storage
- Ezetimibe (SCH-58235) Stability
- Ezetimibe (SCH-58235) Molecular Weight
- Ezetimibe (SCH-58235) SMILES
- Ezetimibe (SCH-58235) CAS Number
- Ezetimibe (SCH-58235) Chemical Structure (2D and 3D)
- Ezetimibe (SCH-58235) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.