Numerous clinical trials evaluate estradiol across diverse indications, including metastatic breast cancer, contraception, atrophic vaginitis, systemic scleroderma, and infertility. Encompassing all research phases from Early Phase 1 through Phase 4 post-marketing evaluations, these studies are sponsored by both major pharmaceutical companies and academic institutions. Recruitment statuses range from completed therapeutic equivalence studies to active or upcoming protocols in hormone receptor-positive oncology settings.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07574216 | NOT_YET_RECRUITING | Post-menopause; Pre-menopause; Sexual Function; Menopause; Vaginal Dryness; Painful Intercourse |
University of Arizona |
2026-06-01 | |
| NCT07420218 | NOT_YET_RECRUITING | Perimenopausal Women |
University of Delaware |
2026-09-01 | PHASE4 |
| NCT07526948 | NOT_YET_RECRUITING | Menopausal Complaints; Vaginal Atrophy; Genitourinary Symptoms; HIV (Human Immunodeficiency Virus); Menopause Related Conditions; Vaginitis; Perimenopause |
Albert Einstein College of Medicine |
2026-09 | PHASE4 |
| NCT07536763 | NOT_YET_RECRUITING | Contraception |
Dr. Hang Wun Raymond Li |
2026-07 | PHASE3 |
| NCT07041814 | NOT_YET_RECRUITING | Turner Syndrome |
Universiti Kebangsaan Malaysia Medical Centre |
2026-02-15 | PHASE2 |
| NCT06369363 | NOT_YET_RECRUITING | Postmenopausal Symptoms; Cardiovascular Diseases |
Milton S. Hershey Medical Center |
2026-09 | EARLY_PHASE1 |
| NCT07620587 | RECRUITING | Energy Balance; Physiology - Regulation of Appetite and Food Intake |
Wilfrid Laurier University |
2026-06-01 | |
| NCT06439524 | RECRUITING | Endometriosis |
Main Line Health |
2024-08-15 | PHASE3 |
| NCT06610305 | RECRUITING | Major Depressive Disorder |
University of North Carolina, Chapel Hill |
2024-09-02 | PHASE4 |
| NCT07568574 | ENROLLING_BY_INVITATION | Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes |
Enhanced Emirates Limited |
2026-03-12 | |
| NCT07544966 | NOT_YET_RECRUITING | Depression - Major Depressive Disorder; Irritability |
University of North Carolina, Chapel Hill |
2026-10-01 | PHASE4 |
| NCT07340190 | RECRUITING | Advanced Malignancies |
Novartis Pharmaceuticals |
2026-06-12 | PHASE1 |
| NCT07419594 | RECRUITING | PTSD; Intrusive Memories; Intrusion Symptom; Trauma; Intrusion |
Charite University, Berlin, Germany |
2024-08-19 | |
| NCT05900895 | RECRUITING | Metastatic Breast Cancer |
Mary D Chamberlin |
2024-07-15 | PHASE1 |
| NCT04833140 | ACTIVE_NOT_RECRUITING | NASH - Nonalcoholic Steatohepatitis |
Massachusetts General Hospital |
2021-12-02 | PHASE3 |
| NCT07013643 | RECRUITING | Healthy Participants |
AstraZeneca |
2025-06-04 | PHASE1 |
| NCT04783857 | RECRUITING | Smoking; Smoking Cessation; Smoking Reduction |
University of Minnesota |
2022-04-14 | PHASE4 |
| NCT07525791 | RECRUITING | Overweight; Obesity |
Novo Nordisk A/S |
2026-04-07 | PHASE1 |
| NCT07568509 | RECRUITING | Arginine Vasopressin Deficiency; Oxytocin Deficiency; Pediatric Disease; Hypopituitarism |
Massachusetts General Hospital |
2026-08-17 | EARLY_PHASE1 |
| NCT06179303 | RECRUITING | Anatomic Stage III Breast Cancer AJCC v8; Anatomic Stage IV Breast Cancer AJCC v8; Locally Advanced Unresectable HER2-Negative Breast Carcinoma; Locally Advanced Unresectable Hormone Receptor-Positive Breast Carcinoma; Metastatic HER2-Negative Breast Carcinoma; Metastatic Hormone Receptor-Positive Breast Carcinoma |
University of Washington |
2024-07-22 | PHASE2 |
| NCT05723601 | ACTIVE_NOT_RECRUITING | Recurrent Urinary Tract Infection |
Wake Forest University Health Sciences |
2024-01-12 | PHASE4 |
| NCT04685148 | RECRUITING | Major Depressive Disorder; Postpartum Depression |
Vibe G Frøkjær, MD, PhD |
2021-02-03 | PHASE1; PHASE2 |
| NCT07446400 | RECRUITING | Healthy Volunteers |
Otsuka Pharmaceutical Development & Commercialization, Inc. |
2026-03-31 | PHASE1 |
| NCT06798571 | RECRUITING | Menopause; Aging |
Penn State University |
2025-03-01 | PHASE4 |
| NCT07083635 | RECRUITING | Menstruation Disturbances; Metrorrhagia; Uterine Hemorrhage; Contraception Behavior |
Chulalongkorn University |
2025-07-29 | PHASE2 |
| NCT07381569 | NOT_YET_RECRUITING | Abortion, Induced |
Peking Union Medical College Hospital |
2026-03-01 | |
| NCT06343870 | RECRUITING | Menopause; Testosterone Deficiency; Estrogen Deficiency |
University of Sao Paulo General Hospital |
2025-12-18 | PHASE3 |
| NCT07502417 | COMPLETED | Healthy Volunteer |
AbbVie |
2026-03-27 | PHASE1 |
| NCT07379502 | NOT_YET_RECRUITING | PCOS (Polycystic Ovary Syndrome) |
CMH Kharian Medical College |
2026-03-05 | |
| NCT07242131 | RECRUITING | Polycystic Ovary Syndrome (PCOS) |
Ege University |
2025-12-01 | |
| NCT07754630 | ACTIVE_NOT_RECRUITING | Menopause; Hypoestrogenism; Hormonal Therapy |
Nutrindo Ideais Research Center |
2025-02-25 | PHASE2 |
| NCT06460948 | COMPLETED | Arginine Vasopressin Deficiency; Oxytocin Deficiency |
Elizabeth Austen Lawson |
2024-11-13 | EARLY_PHASE1 |
| NCT07269327 | COMPLETED | Fertility |
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany |
2025-11-24 | PHASE1 |
| NCT07727863 | COMPLETED | PCOS GnRH Antagonist and GnRH Agonist IVF/ICSI Cycles; IVF Outcomes |
Cairo University |
2024-09-13 | |
| NCT07272889 | COMPLETED | Healthy Volunteer Study |
Atea Pharmaceuticals, Inc. |
2025-12-04 | PHASE1 |
| NCT06942936 | COMPLETED | Healthy Participants |
AstraZeneca |
2025-05-28 | PHASE1 |
| NCT07160504 | RECRUITING | Vagina Atrophy |
University of Aarhus |
2025-03-21 | PHASE4 |
| NCT04828824 | COMPLETED | Contraception Behavior |
University of Colorado, Denver |
2021-06-18 | PHASE4 |
| NCT06279195 | WITHDRAWN | Pelvic Pain |
Endeavor Health |
2024-06-01 | PHASE2 |
| NCT03873428 | UNKNOWN | FES TEP in Detection of Estrogen Receptors |
Centre Georges Francois Leclerc |
2021-10-18 | |
| NCT04597099 | UNKNOWN | PCOS; Polycystic Ovary Syndrome |
University of Virginia |
2022-10-26 | EARLY_PHASE1 |
| NCT03401047 | RECRUITING | Polycystic Ovary Syndrome |
University of Virginia |
2017-11-30 | EARLY_PHASE1 |
| NCT01425541 | UNKNOWN | Hyperandrogenemia; Polycystic Ovary Syndrome (PCOS) |
University of Virginia |
2000-04 | |
| NCT05551949 | COMPLETED | Recurrent Urinary Tract Infection; Urinary Tract Infections; Cystitis Recurrent |
Johns Hopkins University |
2022-01-01 | PHASE4 |
| NCT05982470 | UNKNOWN | Cerebral Small Vessel Diseases; Postmenopausal Symptoms; Mild Cognitive Impairment; White Matter Hyperintensity |
Beijing Tiantan Hospital |
2023-08-18 | PHASE2 |
| NCT04447872 | UNKNOWN | Infertility; Diminished Ovarian Reserve; IVF |
Northwell Health |
2020-09-15 | |
| NCT03973229 | COMPLETED | PTSD; Trauma |
Emory University |
2019-11-11 | EARLY_PHASE1 |
| NCT06461039 | COMPLETED | Obesity |
Novo Nordisk A/S |
2024-06-14 | PHASE1 |
| NCT06799884 | COMPLETED | Drug Drug Interaction |
Idorsia Pharmaceuticals Ltd. |
2025-01-18 | PHASE1 |
| NCT05896384 | COMPLETED | Healthy |
Boehringer Ingelheim |
2023-12-21 | PHASE1 |
| NCT06657105 | COMPLETED | Healthy Participants |
AstraZeneca |
2024-11-01 | PHASE1 |
| NCT03976544 | TERMINATED | Miscarriage; Frozen Embryo Transfer; Natural Cycle; Hormone Replacement Therapy Cycle; Preimplantation Genetic Screening; Euploid Embryos |
CRG UZ Brussel |
2019-05-25 | PHASE4 |
| NCT02330757 | UNKNOWN | Infertility |
Mansoura University |
2016-10-10 | PHASE4 |
| NCT06358014 | UNKNOWN | Postmenopausal Depression; Estrogen |
Xiao Wang |
2023-05-12 | |
| NCT06191289 | TERMINATED | Suicide |
University of Illinois at Chicago |
2024-03-16 | PHASE2 |
| NCT05780489 | UNKNOWN | Infertility, Female; Reproductive Sterility |
Instituto Valenciano de Infertilidad, IVI VALENCIA |
2023-04-14 | |
| NCT06181305 | UNKNOWN | IVF |
Rahem Fertility Center |
2024-02-24 | PHASE4 |
| NCT04595682 | COMPLETED | Alcohol Use, Unspecified |
Mark Fillmore |
2021-03-15 | |
| NCT05663892 | ACTIVE_NOT_RECRUITING | Hiv; Transgenderism |
Maple Leaf Research |
2022-11-23 | PHASE4 |
| NCT06508944 | COMPLETED | Lower Urinary Tract Symptoms; Female Genitourinary Disease; Urinary Stress Incontinence; Urinary Urge Incontinence; Nocturia; Quality of Life; Voiding Disorders; Vagina Atrophy; Urethral Atrophy; Overactive Bladder; Overactive Bladder Syndrome; Bladder, Overactive |
Mahidol University |
2024-04-08 | PHASE4 |
| NCT06654570 | COMPLETED | Breast Cancer |
Helsinki University Central Hospital |
2020-04-08 | PHASE2 |
| NCT06310616 | COMPLETED | HIV Infections |
ViiV Healthcare |
2024-03-06 | PHASE1 |
| NCT03941730 | ACTIVE_NOT_RECRUITING | Advanced Triple-Negative Breast Carcinoma; Anatomic Stage III Breast Cancer AJCC v8; Anatomic Stage IV Breast Cancer AJCC v8; Metastatic Triple-Negative Breast Carcinoma; Recurrent Breast Carcinoma |
Mayo Clinic |
2019-08-28 | PHASE2 |
| NCT06039826 | COMPLETED | Overweight |
Eli Lilly and Company |
2023-09-12 | PHASE1 |
| NCT06354257 | COMPLETED | Tuberculosis |
GlaxoSmithKline |
2024-04-05 | PHASE1 |
| NCT05227391 | UNKNOWN | PCOS |
Reproductive & Genetic Hospital of CITIC-Xiangya |
2022-03-16 | |
| NCT03271489 | COMPLETED | Heavy Menstrual Bleeding; Uterine Fibroids |
AbbVie |
2017-09-13 | PHASE3 |
| NCT06380205 | COMPLETED | Healthy Participants |
Incyte Corporation |
2024-05-07 | PHASE1 |
| NCT05900895 | Not yet recruiting | Metastatic Breast Cancer |
Mary D Chamberlin|Dartmouth-Hitchcock Medical Center |
2024-05 | Phase 1 |
| NCT06380205 | Recruiting | Healthy Participants |
Incyte Corporation |
2024-05-07 | Phase 1 |
| NCT06334315 | Not yet recruiting | Contraception|Pharmacogenomic Drug Interaction |
Yale University|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
2024-05 | Phase 4 |
| NCT06250205 | COMPLETED | Healthy Volunteers |
NewAmsterdam Pharma |
2024-02-05 | PHASE1 |
| NCT06233071 | UNKNOWN | Healthy Subjects |
Bio-innova Co., Ltd |
2024-02-13 | PHASE1 |
| NCT05802303 | TERMINATED | Frozen Embryo Transfer; Infertility, Female |
Indira IVF Hospital Pvt Ltd |
2023-07-25 | |
| NCT05617820 | COMPLETED | Dyspareunia |
Teva Pharmaceuticals USA |
2022-11-15 | PHASE3 |
| NCT03844412 | COMPLETED | Vestibulodynia; Temporomandibular Disorder; Fibromyalgia Syndrome; Irritable Bowel Syndrome; Migraines; Tension Headache; Endometriosis; Interstitial Cystitis; Back Pain; Chronic Fatigue Syndrome |
Duke University |
2019-11-04 | PHASE2 |
| NCT05232344 | COMPLETED | Infertility |
University Hospital, Montpellier |
2022-04-13 | |
| NCT04590417 | ACTIVE_NOT_RECRUITING | Drug Interaction |
Thai Red Cross AIDS Research Centre |
2022-01-24 | |
| NCT03106454 | COMPLETED | Contraception; Ovulation |
University of Southern California |
2014-08 | PHASE3 |
| NCT03981341 | UNKNOWN | Sleep Apnea; Post Menopausal; Oxidative Stress |
Laval University |
2019-11-01 | PHASE3 |
| NCT05951413 | UNKNOWN | IVF |
Beni-Suef University |
2023-06-30 | PHASE2; PHASE3 |
| NCT06144814 | COMPLETED | Vulvovaginal Atrophy |
Koru Health Groups |
2023-04-05 | |
| NCT03815929 | COMPLETED | Cardiovascular Risk Reduction |
Mayo Clinic |
2019-03-15 | PHASE2 |
| NCT06316206 | COMPLETED | Endometrial Polyp; Endometrial Diseases |
University of Palermo |
2023-01-01 | PHASE4 |
| NCT06324851 | COMPLETED | Endometrial Polyp; Endometrial Diseases |
University of Palermo |
2023-01-01 | PHASE4 |
| NCT05010707 | COMPLETED | Transgenderism |
Washington University School of Medicine |
2021-08-02 | PHASE2 |
| NCT05706753 | COMPLETED | Healthy Female |
Janssen Pharmaceutica N.V., Belgium |
2023-01-25 | PHASE1 |
| NCT07398924 | COMPLETED | Female Infertility; Anovulatory Infertility; Unexplained Infertility |
Yuzuncu Yil University |
2022-01-06 | |
| NCT04190927 | UNKNOWN | Menopause; Perimenopausal Disorder; Menopause Related Conditions |
Women's Hormone Network |
2020-06-01 | PHASE4 |
| NCT05579574 | COMPLETED | Healthy Participants |
Bristol-Myers Squibb |
2022-10-21 | PHASE1 |
| NCT05458375 | TERMINATED | Pelvic Organ Prolapse; Urinary Incontinence; Pessary Ulcer of Vagina; Vaginal Atrophy |
University of South Florida |
2022-12-29 | EARLY_PHASE1 |
| NCT05300841 | UNKNOWN | PCOS; ICSI |
Sohag University |
2022-05-01 | EARLY_PHASE1 |
| NCT05161338 | COMPLETED | Infertility, Female |
Instituto Valenciano de Infertilidad, IVI VALENCIA |
2022-02-15 | |
| NCT03726931 | COMPLETED | Breast Cancer |
Amsterdam UMC, location VUmc |
2018-11-13 | |
| NCT03442504 | UNKNOWN | Metastatic Breast Cancer |
Institut Cancerologie de l'Ouest |
2017-03-15 | |
| NCT05505162 | COMPLETED | Healthy Female Participants |
AstraZeneca |
2022-08-24 | PHASE1 |
| NCT05367973 | COMPLETED | Vulvovaginal Atrophy; Vasomotor Symptoms |
Daré Bioscience, Inc. |
2022-04-11 | PHASE1; PHASE2 |
| NCT04021017 | WITHDRAWN | Anorexia Nervosa |
University of Saskatchewan |
2020-01-21 | PHASE1 |
| NCT05556317 | UNKNOWN | Sleep Disturbances and Insomnia |
Cairo University |
2022-09-30 | |
| NCT04150731 | COMPLETED | Breast Cancer |
University of Aarhus |
2020-10-23 | PHASE1; PHASE2 |
| NCT01973816 | COMPLETED | Endometriosis |
University Hospital, Rouen |
2014-09-09 | PHASE3 |
| NCT03745144 | COMPLETED | Relapsing Multiple Sclerosis (RMS) |
Merck KGaA, Darmstadt, Germany |
2019-01-17 | PHASE1 |
| NCT05156814 | UNKNOWN | Perimenopausal Disorder; Hot Flashes |
Scientific Research Institute of Public Health, Russian Federation |
2021-11-29 | PHASE4 |
| NCT03047330 | COMPLETED | Menopause |
Brigham and Women's Hospital |
2017-07-15 | PHASE4 |
| NCT05093205 | COMPLETED | Healthy Adults |
Pfizer |
2021-10-25 | PHASE1 |
| NCT05184777 | COMPLETED | Infertility, Female; Reproductive Sterility |
Instituto Valenciano de Infertilidad, IVI VALENCIA |
2022-02-03 | |
| NCT04278755 | TERMINATED | Bulimia Nervosa; Binge Eating; Eating Disorders; Binge-Eating Disorder |
University of North Carolina, Chapel Hill |
2020-09-24 | PHASE2 |
| NCT04225221 | COMPLETED | Bulimia Nervosa |
University of North Carolina, Chapel Hill |
2020-02-24 | PHASE2 |
| NCT05332106 | COMPLETED | Bioequivalence |
Laboratorios Andromaco S.A. |
2022-03-12 | PHASE1 |
| NCT03416764 | UNKNOWN | Posttraumatic Stress Disorder (PTSD) |
Tel-Aviv Sourasky Medical Center |
2019-01-13 | |
| NCT04934696 | COMPLETED | Healthy Participants |
Bristol-Myers Squibb |
2021-08-03 | PHASE1 |
| NCT03654274 | COMPLETED | Endometriosis |
Myovant Sciences GmbH |
2018-05-22 | PHASE3 |
| NCT05064332 | COMPLETED | Healthy |
Pfizer |
2021-10-08 | PHASE1 |
| NCT00303784 | UNKNOWN | Anemia; Cardiovascular Complications; Hot Flashes; Osteoporosis; Prostate Cancer |
University College, London |
2006-03 | PHASE3 |
| NCT05774405 | COMPLETED | COVID-19; Hormone Replacement Therapy |
Istanbul University - Cerrahpasa |
2020-07-01 | PHASE2 |
| NCT01822288 | COMPLETED | Menopausal Syndromes |
Far Eastern Memorial Hospital |
2012-11-16 | PHASE4 |
| NCT06116201 | COMPLETED | Transgender Women |
Chulalongkorn University |
2020-08-15 | |
| NCT04272008 | COMPLETED | Contraception |
TherapeuticsMD |
2020-03-06 | PHASE1 |
| NCT03809546 | COMPLETED | Differential Female Response to Δ9-tetrahydrocannabinol (THC) |
University of Chicago |
2018-11-06 | EARLY_PHASE1 |
| NCT03724955 | WITHDRAWN | Cystic Fibrosis Related Bone Disease |
Emory University |
2019-04 | PHASE4 |
| NCT05418426 | COMPLETED | Vulvovaginal Atrophy; Vasomotor Symptoms |
Daré Bioscience, Inc. |
2020-08-18 | PHASE1 |
| NCT05143723 | UNKNOWN | Infertility |
Kuban State Medical University |
2020-01-20 | PHASE2 |
| NCT04002635 | WITHDRAWN | Infertility, Female; Polycystic Ovary Syndrome; IVF; Ovulation Disorder |
CRG UZ Brussel |
2020-12-01 | PHASE4 |
| NCT03930706 | COMPLETED | Infertility |
Universitair Ziekenhuis Brussel |
2018-10-01 | |
| NCT04714554 | COMPLETED | Healthy |
Myovant Sciences GmbH |
2021-01-06 | PHASE1 |
| NCT05197374 | COMPLETED | Female Infertility |
Alexandria University |
2020-06-01 | PHASE4 |
| NCT04230070 | COMPLETED | Bioequivalence |
Laboratorios Andromaco S.A. |
2020-10-24 | PHASE1 |
| NCT04093518 | UNKNOWN | Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorders |
Tangent Data |
2019-12-02 | PHASE3 |
| NCT03890042 | COMPLETED | Adenomyosis |
Assiut University |
2019-03-01 | |
| NCT04309643 | COMPLETED | Healthy Volunteers |
Concert Pharmaceuticals |
2020-06-09 | PHASE1 |
| NCT02460445 | COMPLETED | Hyperandrogenism; Metabolic Cardiovascular Syndrome |
Manuel Luque Ramírez |
2015-01 | |
| NCT01265017 | WITHDRAWN | Type 1 Diabetes |
Sansum Diabetes Research Institute |
2012-07 | PHASE1 |
| NCT03003949 | TERMINATED | Perimenopausal Disorder; Stress, Emotional |
University of North Carolina, Chapel Hill |
2017-01-24 | PHASE4 |
| NCT03213457 | COMPLETED | Endometriosis |
AbbVie |
2017-07-07 | PHASE3 |
| NCT03412890 | COMPLETED | Heavy Menstrual Bleeding; Uterine Fibroid |
Myovant Sciences GmbH |
2017-10-19 | PHASE3 |
| NCT04142762 | COMPLETED | Chronic Hepatitis B |
Assembly Biosciences |
2019-10-18 | PHASE1 |
| NCT03854175 | UNKNOWN | Infertility |
Cairo University |
2019-02 | |
| NCT03832894 | UNKNOWN | Infertility |
Cairo University |
2018-12-01 | PHASE3 |
| NCT04018274 | COMPLETED | Healthy |
Pfizer |
2019-08-09 | PHASE1 |
| NCT04709094 | COMPLETED | Healthy |
Alexion Pharmaceuticals, Inc. |
2019-07-28 | PHASE1 |
| NCT03675581 | COMPLETED | Scleroderma, Systemic |
Boehringer Ingelheim |
2018-11-08 | PHASE1 |
| NCT01980680 | COMPLETED | Infertility |
Peter Humaidan |
2014-12 | PHASE4 |
| NCT02705963 | COMPLETED | Solid Tumors |
Novartis Pharmaceuticals |
2016-10-20 | PHASE1 |
| NCT03984825 | COMPLETED | HIV Infections |
ViiV Healthcare |
2019-06-13 | PHASE1 |
| NCT03788681 | UNKNOWN | ICSI |
Ain Shams University |
2018-04-01 | PHASE3 |
| NCT06312033 | COMPLETED | Emotion Regulation; Estradiol |
International Research Training Group 2804 |
2018-08-01 | |
| NCT04964193 | COMPLETED | Drug Use |
PT Sydna Farma |
2019-03-12 | |
| NCT03049735 | COMPLETED | Heavy Menstrual Bleeding; Uterine Fibroid |
Myovant Sciences GmbH |
2017-04-26 | PHASE3 |
| NCT02859285 | COMPLETED | Hypoactive Sexual Desire Disorder |
ProHealth Care, Inc |
2016-04 | |
| NCT01301183 | COMPLETED | Anorexia Nervosa |
Massachusetts General Hospital |
2011-02 | PHASE3 |
| NCT03662516 | COMPLETED | Healthy Females |
Pfizer |
2018-09-26 | PHASE1 |
| NCT03608241 | COMPLETED | Healthy Females |
Pfizer |
2018-09-21 | PHASE1 |
| NCT04418908 | COMPLETED | Type 1 Diabetes |
University of Colorado, Denver |
2010-11-24 | |
| NCT02255175 | COMPLETED | Perimenopausal Depression |
University of North Carolina, Chapel Hill |
2015-10-01 | PHASE4 |
| NCT03506399 | WITHDRAWN | Healthy |
Eli Lilly and Company |
2018-06 | PHASE1 |
| NCT02744131 | UNKNOWN | Polycystic Ovary Syndrome |
Kar Clinic & Hospital Pvt. Ltd. |
2016-05 | |
| NCT02238808 | ACTIVE_NOT_RECRUITING | Estrogen Receptor Positive Breast Cancer |
AHS Cancer Control Alberta |
2015-08 | PHASE2 |
| NCT03353857 | COMPLETED | Biological Availability |
Bayer |
2017-11-29 | PHASE1 |
| NCT03301233 | COMPLETED | Endometrial Thickness |
Ain Shams University |
2017-11-01 | |
| NCT03120728 | UNKNOWN | Emergency Contraception; Healthy, Reproductive Age Women |
University of Southern California |
2017-07-10 | PHASE4 |
| NCT02475265 | COMPLETED | Anorexia Nervosa; Osteoporosis |
Massachusetts General Hospital |
2015-07 | PHASE2 |
| NCT03210246 | COMPLETED | Clinical Trial ,Phase I |
Bayer |
2017-07-17 | PHASE1 |
| NCT03091595 | COMPLETED | Prevention of Pregnancy |
Estetra |
2017-02-07 | PHASE2 |
| NCT03346317 | UNKNOWN | Intrauterine Adhesion |
Beijing Obstetrics and Gynecology Hospital |
2017-11-16 | |
| NCT03069781 | WITHDRAWN | Muscle Atrophy |
McMaster University |
2017-05 | EARLY_PHASE1 |
| NCT03332303 | COMPLETED | Vulvar and Vaginal Atrophy |
Prasco LLC |
2017-10-26 | PHASE3 |
| NCT03236740 | COMPLETED | PCOS |
S.C.B. Medical College and Hospital |
2017-08-01 | PHASE4 |
| NCT03077555 | COMPLETED | Ovulation Inhibition |
Mahidol University |
2017-01-21 | PHASE4 |
| NCT03238092 | UNKNOWN | Fertility Disorders |
Hospital de Clinicas de Porto Alegre |
2017-08 | PHASE3 |
| NCT03262740 | COMPLETED | Rheumatoid Arthritis |
Bristol-Myers Squibb |
2017-09-11 | PHASE1 |
| NCT01941134 | WITHDRAWN | Bariatric Surgery Candidate; Contraception |
Johns Hopkins University |
2013-04 | PHASE4 |
| NCT02751385 | TERMINATED | Carcinoma, Non-Small-Cell Lung |
Boehringer Ingelheim |
2016-05-20 | PHASE1 |
| NCT03262727 | COMPLETED | Systemic Lupus Erythematosus; Arthritic Psoriasis; Psoriasis; Inflammatory Bowel Diseases |
Bristol-Myers Squibb |
2017-09-01 | PHASE1 |
| NCT03720847 | COMPLETED | Suicidal Ideation |
University of North Carolina, Chapel Hill |
2016-12-31 | PHASE4 |
| NCT02697851 | TERMINATED | HIV |
St Stephens Aids Trust |
2016-07 | PHASE1 |
| NCT02957630 | COMPLETED | Contraception; Liver Metabolism; Hemostasis Parameter |
Estetra |
2016-09 | PHASE1; PHASE2 |
| NCT03155048 | COMPLETED | Infertility |
Memorial Sisli Hospital, Istanbul |
2017-05-01 | |
| NCT02617537 | WITHDRAWN | Dysmenorrhea |
Bayer |
2016-01 | PHASE3 |
| NCT01428193 | TERMINATED | Polycystic Ovary Syndrome; Hyperandrogenism |
University of Virginia |
2006-09 | |
| NCT03126097 | TERMINATED | Healthy |
Janssen Research & Development, LLC |
2017-04-13 | PHASE1 |
| NCT02292732 | WITHDRAWN | Cancer |
GlaxoSmithKline |
2016-02 | PHASE1 |
| NCT02866786 | COMPLETED | Polycystic Ovary Syndrome |
S.C.B. Medical College and Hospital |
2016-08-15 | PHASE4 |
| NCT02846142 | COMPLETED | Healthy Volunteer |
Proteostasis Therapeutics, Inc. |
2016-06 | PHASE1 |
| NCT02626208 | COMPLETED | Suppression of Ovulation |
Premier Research |
2016-01 | PHASE2 |
| NCT03294538 | COMPLETED | Atrophic Vaginitis |
Actavis Inc. |
2016-05-18 | PHASE3 |
| NCT03333564 | COMPLETED | Vitamin D Deficiency |
Applied Science Private University |
2016-11 | |
| NCT02845219 | COMPLETED | Diabetes; Diabetes Mellitus, Type 2 |
Novo Nordisk A/S |
2016-07 | PHASE1 |
| NCT02531321 | TERMINATED | Contraception; HIV |
University of Southern California |
2015-08 | PHASE4 |
| NCT01942668 | COMPLETED | Menopause |
TherapeuticsMD |
2013-08-05 | PHASE3 |
| NCT02832180 | COMPLETED | Arthritis |
Bristol-Myers Squibb |
2016-05 | PHASE1 |
| NCT01862835 | COMPLETED | Normal Healthy Volunteers |
Mayo Clinic |
2013-05 | PHASE1 |
| NCT02668796 | COMPLETED | Vulvar and Vaginal Atrophy |
Glenmark Pharmaceuticals Ltd. India |
2016-01 | PHASE3 |
| NCT03848234 | COMPLETED | Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorders |
Tangent Data |
2015-12-04 | PHASE3 |
| NCT02652650 | COMPLETED | Healthy |
Janssen Research & Development, LLC |
2015-12 | PHASE1 |
| NCT02218463 | COMPLETED | Prepubertal Labial Adhesions |
Children's Mercy Hospital Kansas City |
2014-09 | |
| NCT02271282 | COMPLETED | Normal Healthy Volunteers |
Mayo Clinic |
2014-12 | PHASE1 |
| NCT02533427 | COMPLETED | HCV Infection |
Gilead Sciences |
2015-10-29 | PHASE1 |
| NCT01308814 | COMPLETED | Perimenopause; Menopause; Depression |
University of North Carolina, Chapel Hill |
2010-10 | PHASE2; PHASE3 |
| NCT02480881 | COMPLETED | Infection, Human Immunodeficiency Virus |
ViiV Healthcare |
2015-07-07 | PHASE1 |
| NCT02333253 | COMPLETED | Other Complications Associated With Artificial Fertilization |
Cairo University |
2015-01 | PHASE3 |
| NCT02847806 | COMPLETED | Hypogonadism |
University Hospital, Caen |
2008-01 | PHASE3 |
| NCT02161614 | COMPLETED | Flow-mediated Dilation Evaluation of the Brachial Artery |
Federal University of Minas Gerais |
2014-02 | |
| NCT01165307 | COMPLETED | Menorrhagia |
Abimbola Famuyide |
2009-08 | PHASE4 |
| NCT02316249 | WITHDRAWN | Atrophy of Vagina; Vaginal Ulceration; Vaginitis |
Northwell Health |
2015-04 | PHASE2 |
| NCT00030147 | COMPLETED | Perimenopausal Depression; Depression |
National Institute of Mental Health (NIMH) |
2002-02 | PHASE4 |
| NCT01638923 | COMPLETED | Metrorrhagia |
Bayer |
2012-06 | PHASE3 |
| NCT01723579 | WITHDRAWN | Contraception |
Organon and Co |
2013-07 | PHASE3 |
| NCT00997893 | COMPLETED | Menopause; Hot Flashes |
University of Illinois at Chicago |
2009-12 | PHASE2 |
| NCT01586000 | COMPLETED | Suppression of Ovulation |
Kimberly Myer |
2012-03 | PHASE2 |
| NCT02215395 | COMPLETED | Antifungal Drug Adverse Reaction |
Population Council |
2014-03 | PHASE1 |
| NCT01480778 | COMPLETED | Irregular Periods |
Azidus Brasil |
2014-07 | PHASE3 |
| NCT01953809 | WITHDRAWN | Infections, Bacterial |
GlaxoSmithKline |
2014-08 | PHASE1 |
| NCT02027337 | UNKNOWN | Polycystic Ovarian Syndrome; Hyperandrogenism; Menstrual Irregularities |
Tyumen State Medical Academy |
2013-12 | PHASE4 |
| NCT02872818 | COMPLETED | Apoptotic Signal Pathways in Endometrial Hyperplasia |
Kayseri Education and Research Hospital |
2014-10 | PHASE4 |
| NCT02021097 | UNKNOWN | Oral Contraceptive |
Regenex Pharmaceutical, China |
2012-02 | PHASE3 |
| NCT01360996 | COMPLETED | Polycystic Ovary Syndrome |
Woman's |
2011-08 | PHASE4 |
| NCT01427595 | COMPLETED | Polycystic Ovary Syndrome; Hyperandrogenism |
University of Virginia |
2009-02-18 | |
| NCT01798836 | TERMINATED | Infertility |
National and Kapodistrian University of Athens |
2013-02 | PHASE2; PHASE3 |
| NCT01780610 | UNKNOWN | Infertility |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2012-01 | |
| NCT01780558 | UNKNOWN | Infertility |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2010-01 | |
| NCT01714128 | WITHDRAWN | Breast Cancer |
Washington University School of Medicine |
2013-06 | |
| NCT02195986 | COMPLETED | Atrophic Vaginitis |
Mylan Pharmaceuticals Inc |
2014-06 | PHASE3 |
| NCT02159131 | COMPLETED | Infections, Human Immunodeficiency Virus and Hepatitis |
ViiV Healthcare |
2014-08 | PHASE1 |
| NCT01810315 | COMPLETED | HIV Prevention |
CONRAD |
2013-09 | PHASE1 |
| NCT02157467 | COMPLETED | Infection, Human Immunodeficiency Virus |
ViiV Healthcare |
2014-06-02 | PHASE1 |
| NCT02080468 | COMPLETED | Healthy |
Aegerion Pharmaceuticals, Inc. |
2014-02-19 | PHASE1 |
| NCT01065220 | COMPLETED | Transsexualism |
Medical University of Vienna |
2010-02 | PHASE4 |
| NCT01941615 | TERMINATED | Healthy |
Boehringer Ingelheim |
2013-11 | PHASE1 |
| NCT01268046 | COMPLETED | Memory Loss; Cognitive Changes; Postmenopausal Symptoms |
Massachusetts General Hospital |
2009-11 | PHASE1; PHASE2 |
| NCT01805817 | WITHDRAWN | Contraceptive Methods Comparison |
Istanbul Training and Research Hospital |
2012-12 | PHASE4 |
| NCT01816139 | COMPLETED | Vulvovaginal Atrophy |
Warner Chilcott |
2013-01-31 | PHASE3 |
| NCT01441635 | COMPLETED | Heavy Uterine Bleeding; Uterine Fibroids |
AbbVie (prior sponsor, Abbott) |
2011-09-08 | PHASE2 |
| NCT01709318 | COMPLETED | Contraception |
Organon and Co |
2012-12-12 | PHASE2 |
| NCT03359057 | COMPLETED | Contraception |
Galeno Desenvolvimento de Pesquisas Clínicas |
2013-02-26 | PHASE3 |
| NCT01986764 | WITHDRAWN | Planned RRSO |
University of Pennsylvania |
2013-07-01 | |
| NCT01083641 | TERMINATED | Female Breast Cancer |
University of Wisconsin, Madison |
2010-01 | PHASE2 |
| NCT01023178 | COMPLETED | Ovarian Failure, Premature |
Stanford University |
2007-02 | |
| NCT01850095 | UNKNOWN | Acne; Quality of Life |
Marco Alexandre Dias da Rocha |
2012-03 | |
| NCT01419353 | COMPLETED | Infertility |
Meir Medical Center |
2011-08 | PHASE4 |
| NCT01753102 | TERMINATED | Vulvar Atrophy; Vaginal Atrophy |
Sun Pharmaceutical Industries Limited |
2012-11-06 | PHASE3 |
| NCT00114517 | COMPLETED | Atherosclerosis |
University of Southern California |
2004-07 | PHASE2 |
| NCT01254292 | COMPLETED | Contraception |
Bayer |
2011-01-06 | PHASE3 |
| NCT01418209 | COMPLETED | Hot Flashes; Menopause; Vasomotor Disturbance |
Fred Hutchinson Cancer Center |
2011-11 | |
| NCT01381016 | COMPLETED | Obesity; Infertility |
University of Colorado, Denver |
2011-06 | |
| NCT01615354 | COMPLETED | Healthy Volunteer |
Hoffmann-La Roche |
2012-07 | PHASE1 |
| NCT01490190 | COMPLETED | Contraception |
Organon and Co |
2011-12-26 | PHASE4 |
| NCT01310647 | COMPLETED | Ovarian Diseases |
Instituto de Investigacion Sanitaria La Fe |
2011-06 | PHASE2 |
| NCT00442689 | COMPLETED | Polycystic Ovary Syndrome; Metabolic Syndrome |
Northwestern University |
2006-07 | |
| NCT00608062 | COMPLETED | Arterial Stiffening; Aging; Menopause |
University of Colorado, Denver |
2007-03 | |
| NCT01251263 | UNKNOWN | Menstrual Migraines; Menstrual Bleeding; Menstrual Spotting |
Scott and White Hospital & Clinic |
2010-10 | PHASE4 |
| NCT01448291 | UNKNOWN | Vaginosis, Bacterial |
Eastern Virginia Medical School |
2011-10 | PHASE4 |
| NCT01569113 | COMPLETED | Emergency Contraception |
HRA Pharma |
2012-03 | PHASE4 |
| NCT01257984 | COMPLETED | Contraception |
Bayer |
2010-12 | PHASE3 |
| NCT01546454 | COMPLETED | Coronary Heart Disease |
Oregon Health and Science University |
2012-02 | |
| NCT01597986 | COMPLETED | Pharmacokinetics of Isavuconazole; Pharmacokinetics of Ethinyl Estradiol and Norethindrone; Healthy Volunteers |
Astellas Pharma Global Development, Inc. |
2012-04 | PHASE1 |
| NCT01603745 | UNKNOWN | Polycystic Ovary Syndrome |
Catholic University of the Sacred Heart |
2012-04 | PHASE1 |
| NCT00154180 | UNKNOWN | Menopause; Arteriosclerosis |
Kronos Longevity Research Institute |
2005-09 | PHASE4 |
| NCT00722761 | COMPLETED | Acne Vulgaris |
Massachusetts General Hospital |
2009-04 | PHASE3 |
| NCT01291004 | COMPLETED | Follicle Development; Ovarian Follicle; Follicle Count; Follicle Size; Oral Contraceptive |
Teva Branded Pharmaceutical Products R&D, Inc. |
2011-01-31 | PHASE1 |
| NCT00193726 | TERMINATED | Breast Cancer |
Sudeep Gupta |
2005-07 | PHASE3 |
| NCT01498861 | COMPLETED | Infection, Human Immunodeficiency Virus |
ViiV Healthcare |
2011-12 | PHASE1 |
| NCT02467673 | COMPLETED | Menopausal Syndrome |
University Potiguar |
2012-01 | PHASE2 |
| NCT01109979 | COMPLETED | Cardiovascular Diseases |
Brigham and Women's Hospital |
2009-12 | PHASE4 |
| NCT00370019 | WITHDRAWN | Premature Ovarian Failure |
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
2006-08-25 | PHASE2 |
| NCT00722800 | TERMINATED | Hidradenitis Suppurativa |
Massachusetts General Hospital |
2008-10 | PHASE2 |
| NCT00455962 | COMPLETED | Premenopause; Healthy |
Massachusetts General Hospital |
2005-01 | PHASE1; PHASE2 |
| NCT00357006 | COMPLETED | Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder(Not in Manic Phase) |
The Alfred |
2006-07 | PHASE2 |
| NCT00999479 | WITHDRAWN | Endometrioma |
University of Oklahoma |
2009-10 | |
| NCT01185704 | COMPLETED | Polycystic Ovarian Syndrome |
Merck KGaA, Darmstadt, Germany |
2008-11 | PHASE3 |
| NCT01221831 | COMPLETED | Contraception |
Estetra |
2010-09 | PHASE2 |
| NCT00914693 | COMPLETED | Contraception |
Bayer |
2009-04 | PHASE3 |
| NCT01581814 | COMPLETED | Polycystic Ovary Syndrome |
Catholic University of the Sacred Heart |
2008-10 | PHASE3 |
| NCT00755963 | COMPLETED | Hormone Replacement |
Medical University of Vienna |
2009-05 | PHASE4 |
| NCT01519401 | COMPLETED | Polycystic Ovary Syndrome; Estro-progestin Drugs |
Catholic University of the Sacred Heart |
2010-02 | |
| NCT01459445 | UNKNOWN | Polycystic Ovary Syndrome; Endothelial Dysfunction |
Iuliu Hatieganu University of Medicine and Pharmacy |
2011-02 | |
| NCT01056042 | COMPLETED | Endometriosis |
Prince of Songkla University |
2007-06 | PHASE4 |
| NCT00829114 | COMPLETED | HIV/AIDS; HIV Infections |
FHI 360 |
2009-03 | PHASE4 |
| NCT00324259 | COMPLETED | Breast Neoplasms |
Washington University School of Medicine |
2004-08 | PHASE2 |
| NCT00870220 | TERMINATED | Turner's Syndrome |
University of Chicago |
2009-04 | PHASE1 |
| NCT00910637 | COMPLETED | Contraception |
Bayer |
2009-05-01 | PHASE3 |
| NCT01569945 | COMPLETED | Subfertility |
University Hospital, Gasthuisberg |
2004-09 | |
| NCT01103518 | UNKNOWN | Amenorrhea; Dysmenorrhea; Menstruation Disturbances; Hyperandrogenism |
Fundação Educacional Serra dos Órgãos |
2009-12 | PHASE4 |
| NCT01489852 | COMPLETED | Infertility |
Gemer |
2006-12 | PHASE4 |
| NCT00465894 | COMPLETED | Overactive Bladder |
University of Alabama at Birmingham |
2007-04 | |
| NCT00237042 | COMPLETED | Temporomandibular Joint Disorders |
University of Washington |
2005-10 | |
| NCT01063023 | COMPLETED | Hepatitis C Virus |
Bristol-Myers Squibb |
2010-01 | PHASE1 |
| NCT00089414 | TERMINATED | Premenstrual Syndrome; PMS; Premenstrual Dysphoric Disorder; PMDD; Depression |
National Institute of Mental Health (NIMH) |
2004-07 | PHASE2 |
| NCT00905723 | UNKNOWN | Postmenopausal Symptoms |
Federal University of São Paulo |
2009-05 | PHASE3 |
| NCT00576225 | WITHDRAWN | NSCLC |
CTI BioPharma |
2007-09 | PHASE3 |
| NCT00915915 | COMPLETED | Contraception; Ovulation Inhibition |
Bayer |
2009-06 | PHASE2 |
| NCT01466673 | COMPLETED | Acne Vulgaris |
Janssen-Cilag Ltd.,Thailand |
2008-12 | PHASE4 |
| NCT00983957 | COMPLETED | Chronic Hepatitis C |
Bristol-Myers Squibb |
2009-10 | PHASE1 |
| NCT00701337 | COMPLETED | Postmenopausal |
University Hospital, Toulouse |
2006-09 | PHASE4 |
| NCT00789802 | COMPLETED | Contraception; Bleeding |
Washington University School of Medicine |
2008-11 | |
| NCT00569244 | COMPLETED | Primary Dysmenorrhea |
Bayer |
2007-12 | PHASE3 |
| NCT00567164 | COMPLETED | Contraception; Ovulation Inhibition; Contraceptives, Oral |
Bayer |
2007-10 | PHASE3 |
| NCT00915174 | COMPLETED | Healthy |
Merz Pharmaceuticals GmbH |
2009-06 | PHASE1 |
| NCT00785317 | UNKNOWN | Hormone Replacement Therapy |
Karolinska Institutet |
2008-11 | PHASE4 |
| NCT01668446 | COMPLETED | Endometrial Preparation; Frozen Embryo Transfer |
farzaneh hojjat |
2009-09 | PHASE4 |
| NCT00901290 | SUSPENDED | Pharmacokinetics |
AstraZeneca |
2009-05 | PHASE1 |
| NCT00522873 | COMPLETED | Postmenopause |
Bayer |
2007-08 | PHASE3 |
| NCT00653614 | COMPLETED | Contraceptive, Oral, Hormonal |
Bayer |
2008-03 | PHASE2 |
| NCT00511342 | COMPLETED | Contraception |
Organon and Co |
2006-09 | PHASE3 |
| NCT00145522 | COMPLETED | Menopause |
Solvay Pharmaceuticals |
2005-11 | PHASE4 |
| NCT00821496 | COMPLETED | Healthy |
VIVUS LLC |
2009-01 | PHASE1 |
| NCT01120665 | COMPLETED | Women's Health |
University of Sao Paulo General Hospital |
2002-02 | |
| NCT00740194 | COMPLETED | Healthy |
University Hospital, Ghent |
2008-08 | PHASE1; PHASE2 |
| NCT00537836 | COMPLETED | Vasomotor System |
Bayer |
2007-10 | PHASE2 |
| NCT01367912 | COMPLETED | Infertility |
Zekai Tahir Burak Women's Health Research and Education Hospital |
2008-02 | |
| NCT00685906 | COMPLETED | Healthy |
AstraZeneca |
2008-04 | PHASE1 |
| NCT00196313 | COMPLETED | Dysmenorrhea |
Duramed Research |
2005-05 | PHASE2 |
| NCT00266032 | COMPLETED | Contraception |
Bayer |
2005-12 | PHASE3 |
| NCT01344369 | COMPLETED | Healthy |
Teva Pharmaceuticals USA |
2008-08 | PHASE1 |
| NCT00090857 | COMPLETED | Breast Cancer |
Dana-Farber Cancer Institute |
2002-02 | PHASE2 |
| NCT00468481 | COMPLETED | Neural Tube Defects; Contraception; Oral Contraceptives (OC) |
Bayer |
2007-04 | PHASE3 |
| NCT00612508 | COMPLETED | Contraceptive Usage; Vaginal Epithelial Disruption |
Oregon Health and Science University |
2007-05 | |
| NCT00668603 | COMPLETED | Postmenopausal Vasomotor Symptoms; Cardiovascular Disease |
University of Helsinki |
2005-08 | |
| NCT00511355 | COMPLETED | Contraception |
Organon and Co |
2006-10 | PHASE3 |
| NCT00511433 | COMPLETED | Contraception |
Organon and Co |
2006-10 | PHASE3 |
| NCT01258660 | COMPLETED | Contraception |
Bayer |
2006-12 | PHASE1 |
| NCT00551733 | TERMINATED | Lung Cancer |
CTI BioPharma |
2007-08 | PHASE3 |
| NCT00471991 | COMPLETED | Oral Contraceptive |
Bayer |
2007-04 | PHASE2 |
| NCT00160316 | COMPLETED | Postmenopause |
Solvay Pharmaceuticals |
2005-04 | PHASE3 |
| NCT00191113 | COMPLETED | Turner Syndrome |
Eli Lilly and Company |
1989-02 | PHASE3 |
| NCT00356447 | COMPLETED | Vasomotor Symptoms |
Bayer |
2006-05 | PHASE3 |
| NCT00711607 | COMPLETED | Healthy |
Organon and Co |
2007-05-01 | PHASE1 |
| NCT00593294 | COMPLETED | Polycystic Ovary Syndrome |
Federico II University |
2006-01 | PHASE4 |
| NCT00196365 | COMPLETED | Dysmenorrhea |
Duramed Research |
2005-01 | PHASE3 |
| NCT01253174 | COMPLETED | Contraception |
Bayer |
2006-08 | PHASE1 |
| NCT00196326 | COMPLETED | Contraception |
Duramed Research |
2005-06 | PHASE3 |
| NCT00113100 | COMPLETED | Skin Wrinkling |
University of Michigan |
2004-08 | |
| NCT00108849 | COMPLETED | Menopause; Postmenopausal Vaginal Atrophy |
Novo Nordisk A/S |
2005-03 | PHASE3 |
| NCT01508858 | COMPLETED | Diabetes; Diabetes Mellitus, Type 2 |
Novo Nordisk A/S |
2006-11 | PHASE1 |
| NCT00269620 | COMPLETED | Contraception |
University of Pittsburgh |
2005-06 | PHASE4 |
| NCT00167648 | COMPLETED | Cancer; Prostate Neoplasms |
University of Washington |
2005-03 | PHASE2 |
| NCT00319163 | COMPLETED | Healthy |
Wyeth is now a wholly owned subsidiary of Pfizer |
2006-05 | PHASE1 |
| NCT00732693 | COMPLETED | Premature Ovarian Failure |
University of Edinburgh |
2002-02 | PHASE4 |
| NCT00185237 | COMPLETED | Hot Flashes |
Bayer |
2005-07 | PHASE3 |
| NCT01389102 | COMPLETED | Hot Flashes |
Lumara Health, Inc. |
2004-12 | PHASE3 |
| NCT00212277 | COMPLETED | Dysmenorrhea |
Nobelpharma |
2005-02 | PHASE3 |
| NCT01182194 | COMPLETED | Healthy |
Teva Pharmaceuticals USA |
2006-06 | PHASE1 |
| NCT00161681 | COMPLETED | Premenstrual Syndrome |
Wyeth is now a wholly owned subsidiary of Pfizer |
2005-07 | PHASE3 |
| NCT00236301 | TERMINATED | Healthy Symptomatic Menopausal Women |
Assistance Publique - Hôpitaux de Paris |
2004-03 | PHASE3 |
| NCT00662454 | COMPLETED | Contraception; Body Weight |
Oregon Health and Science University |
2006-01 | PHASE4 |
| NCT00212342 | COMPLETED | Dysmenorrhea |
Nobelpharma |
2004-12 | PHASE3 |
| NCT00413764 | COMPLETED | Sexual Dysfunction |
Organon and Co |
2004-03-23 | PHASE3 |
| NCT00000897 | COMPLETED | HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
||
| NCT01477632 | COMPLETED | Menopause; Healthy |
Novo Nordisk A/S |
2005-03 | PHASE1 |
| NCT00184795 | COMPLETED | Menopause; Menopausal Vasomotor Symptoms |
Novo Nordisk A/S |
2004-05-28 | PHASE3 |
| NCT00431093 | COMPLETED | Menopause |
Organon and Co |
2002-11 | PHASE4 |
| NCT00307632 | COMPLETED | Contraception |
Janssen-Cilag Farmaceutica Ltda. |
2003-02 | PHASE4 |
| NCT01044056 | COMPLETED | Contraception |
Organon and Co |
2004-03 | PHASE4 |
| NCT00805415 | COMPLETED | Ovulation Inhibition |
Bayer |
2003-03 | PHASE2 |
| NCT01070979 | COMPLETED | Hormone Replacement Therapy |
Warner Chilcott |
2003-02 | PHASE3 |
| NCT00650442 | COMPLETED | Healthy |
Mylan Pharmaceuticals Inc |
2003-01 | PHASE1 |
| NCT00860964 | COMPLETED | Osteoporosis |
Peking Union Medical College |
1998-02 | PHASE4 |
| NCT02245438 | TERMINATED | Healthy |
Boehringer Ingelheim |
2002-05 | PHASE1 |
| NCT02182791 | COMPLETED | HIV Infections |
Boehringer Ingelheim |
1998-04 | PHASE1 |
| NCT00465192 | COMPLETED | Menopause; Postmenopausal Vaginal Atrophy |
Novo Nordisk A/S |
1994-08-31 | PHASE3 |
| NCT00001221 | COMPLETED | Gonadal Dysgenesis; Turner's Syndrome |
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
1987-09 | PHASE2 |
| NCT00236782 | COMPLETED | Contraception |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
1997-10 | PHASE3 |
| NCT00490308 | UNKNOWN | Infertility |
Assaf-Harofeh Medical Center |
2007-08 | PHASE1 |
| NCT00236795 | COMPLETED | Contraception; Female Contraception |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
1997-01 | PHASE3 |
| NCT00651469 | COMPLETED | Acne Vulgaris |
Bayer |
2003-01 | PHASE3 |
| NCT00709332 | COMPLETED | Drug Interactions; Contraception; Pharmacokinetics |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2005-01 | PHASE1 |
| NCT00213096 | COMPLETED | Contraception |
Population Council |
2003-03 | PHASE2 |
| NCT00204438 | COMPLETED | Contraception |
University of Saskatchewan |
2002-02 | |
| NCT00005108 | COMPLETED | Atherosclerosis; Healthy; Vascular Disease |
National Heart, Lung, and Blood Institute (NHLBI) |
2000-04 | PHASE2 |
| NCT00195559 | COMPLETED | Premenstrual Syndrome; Menstruation Disturbances |
Wyeth is now a wholly owned subsidiary of Pfizer |
2005-09 | PHASE3 |
| NCT00361075 | COMPLETED | Menopause; Postmenopause; Premenopause; Cardiovascular Disease |
Northwestern University |
1998-07 | PHASE4 |
| NCT00320567 | COMPLETED | Osteoporosis |
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
PHASE2 | |
| NCT00709189 | COMPLETED | Female Contraception; Contraception; Therapeutic Equivalency; Pharmacokinetics |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2005-05 | PHASE1 |
| NCT00651599 | COMPLETED | Vasomotor Symptoms |
Bayer |
2004-07 | PHASE3 |
| NCT00367276 | COMPLETED | Healthy |
Bayer |
2002-12 | PHASE3 |
| NCT00653016 | COMPLETED | Female Contraception |
Janssen-Ortho Inc., Canada |
2002-10 | PHASE4 |
| NCT00428311 | COMPLETED | Polycystic Ovary Syndrome |
Hospital Universitario Ramon y Cajal |
2004-04 | PHASE4 |
| NCT00206622 | COMPLETED | Hot Flashes |
Bayer |
2004-12 | PHASE4 |
| NCT00185328 | COMPLETED | Postmenopause |
Bayer |
2005-09 | PHASE4 |
| NCT00026962 | COMPLETED | Breast Cancer |
National Cancer Institute (NCI) |
1999-09 | PHASE2 |
| NCT00709982 | COMPLETED | Drug Interactions; Healthy; Pharmacokinetics |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2005-05 | PHASE1 |
| NCT00204074 | UNKNOWN | Migraine |
University Hospital, Linkoeping |
2001-10 | PHASE2; PHASE3 |
| NCT00006133 | COMPLETED | Systemic Lupus Erythematosus |
National Center for Research Resources (NCRR) |
2000-06 | |
| NCT00006324 | COMPLETED | HIV Infections |
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
1999-12 | |
| NCT00220324 | COMPLETED | Contraception |
Bayer |
2004-02 | PHASE3 |
| NCT00310531 | COMPLETED | Osteopenia |
Bayer |
2004-02 | PHASE3 |
| NCT00044837 | TERMINATED | HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE1 | |
| NCT00350480 | COMPLETED | Uterine Hemorrhage; Menorrhagia |
Kaiser Permanente |
2003-04 | |
| NCT00463450 | COMPLETED | Hormone Replacement Therapy |
Bayer |
2002-05 | PHASE3 |
| NCT00258063 | COMPLETED | Contraception; Female Contraception |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2004-05 | PHASE1 |
| NCT00344383 | COMPLETED | Metrorrhagia |
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
2003-11 | PHASE2 |
| NCT00391417 | COMPLETED | Hot Flashes |
BioSante Pharmaceuticals |
2003-09 | PHASE3 |
| NCT00117273 | COMPLETED | Healthy |
Duramed Research |
2005-06 | PHASE3 |
| NCT00236769 | COMPLETED | Contraception; Female Contraception |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
1997-11 | PHASE3 |
| NCT00185224 | COMPLETED | Contraception |
Bayer |
2005-03 | PHASE2 |
| NCT00775086 | COMPLETED | Female Contraception |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2004-05 | PHASE1 |
| NCT00102141 | COMPLETED | Hypertension; Postmenopause |
Bayer |
2004-04 | PHASE3 |
| NCT00294463 | COMPLETED | Postmenopause; Osteoporosis |
Erasmus Medical Center |
2003-02 | PHASE4 |
| NCT00206557 | COMPLETED | Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder |
The Alfred |
2002-10 | PHASE2 |
| NCT00004763 | COMPLETED | Hyperandrogenism |
National Center for Research Resources (NCRR) |
1993-01 | PHASE2 |
| NCT00003771 | COMPLETED | Breast Cancer; Menopausal Symptoms |
Regional Oncologic Center |
1997-09 | PHASE3 |
| NCT00435175 | COMPLETED | Postmenopause |
University of Aarhus |
2005-06 |
(data from https://clinicaltrials.gov, updated on 2026-06-17)
Check the
17β-Estradiol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
Note: Technical data last updated: Sep 1, 2026.