CAS No. 74011-58-8

Batch: Purity:99.93
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Enoxacin Chemical Structure
Chemical Structure
Check the Enoxacin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid
CAS Number 74011-58-8
Molecular Formula

C15H17FN4O3
Molecular Weight (MW) 320.32
SMILES CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O
InChIKey IDYZIJYBMGIQMJ-UHFFFAOYSA-N

Ordering Information

Biological Activity

Enoxacin is an oral, broad-spectrum fluoroquinolone antibacterial agent that acts as an inhibitor of bacterial DNA gyrase and topoisomerase IV. By suppressing these essential enzymes, enoxacin interrupts bacterial DNA replication and transcription pathways, leading to inhibition of bacterial cell division and cell death. It exhibits potent antibacterial effects against a broad panel of both Gram-negative and Gram-positive bacterial strains in preclinical models.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 32 mg/mL (99.9 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.