CAS No. 89-25-8
Batch:
Purity:99.89
Chemical Structure
Check the
Edaravone
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 5-methyl-2-phenyl-4H-pyrazol-3-one | |
|---|---|---|
| CAS Number | 89-25-8 | |
| Molecular Formula |
C10H10N2O |
|
| Molecular Weight (MW) | 174.2 | |
| SMILES | CC1=NN(C(=O)C1)C2=CC=CC=C2 | |
| InChIKey | QELUYTUMUWHWMC-UHFFFAOYSA-N |
Edaravone (MCI-186) is a potent free radical scavenger and antioxidant agent. It quenches reactive oxygen species (ROS) and suppresses lipid peroxidation, thereby protecting endothelial and neuronal cells from ROS-mediated oxidative damage. Additionally, edaravone enhances prostacyclin production and inhibits lipoxygenase-mediated arachidonic acid metabolism by trapping hydroxyl radicals, leading to attenuation of cellular oxidative stress.
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
35 mg/mL
(200.91 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
| Water | Insoluble |
| DMSO |
35 mg/mL
(200.91 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 35 mg/mL |
| Water | Insoluble |
| DMSO |
35 mg/mL
(200.91 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 35 mg/mL |
| Water | Insoluble |
| DMSO |
35 mg/mL
(200.91 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 35 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.