CAS No. 16208-51-8

Batch: Purity:99.75
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Dimesna Chemical Structure
Chemical Structure
Check the Dimesna product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 16208-51-8
Molecular Formula

C4H8Na2O6S4
Molecular Weight (MW) 326.34
SMILES C(CS(=O)(=O)[O-])SSCCS(=O)(=O)[O-].[Na+].[Na+]

Ordering Information

Biological Activity

Dimesna is a chemoprotective and uroprotective agent used to reduce chemotherapy-induced toxicity. It functions to protect against cisplatin-induced dose-limiting nephrotoxicity, myelosuppression, and vomiting in preclinical models without causing adverse systemic toxicity. In addition, high systemic doses of dimesna are well tolerated, and the compound demonstrates mucolytic properties as well as selective antitumor activity across specific cancer cell lines.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.