Clinical Trials

Numerous clinical trials evaluate the therapeutic and nutritional applications of this compound across diverse indications, including parenteral nutrition-associated liver disease, metabolic syndrome, pregnancy-related nutritional status, coronary artery disease, colorectal cancer, asthma, and head trauma. Spanning Early Phase 1 through Phase 4 interventions, these active, completed, and recruiting protocols are supported by healthcare and academic sponsors such as Fresenius Kabi, the Public Health Foundation of India, and the University of Leeds.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07322068 NOT_YET_RECRUITING
Malaria, Falciparum
Stanford University
 2026-09 PHASE4
NCT07575438 NOT_YET_RECRUITING
Type 2 Diabetes; Prediabetes (Insulin Resistance, Impaired Glucose Tolerance); Prediabetes / Type 2 Diabetes; Obesity & Overweight; Obesity and Diabetes Mellitus, Type 2
May Faraj, PDt, PhD
 2026-07 PHASE2
NCT06933095 RECRUITING
Eldery People; Cognitive Decline; Memory Decline; DHA CNS Delivery
University of Cincinnati
 2024-09-15
NCT07246525 NOT_YET_RECRUITING
Malaria
University of California, San Francisco
 2026-08-01 PHASE4
NCT06736925 RECRUITING
Subconcussive Head Impact; Omega-3 Fatty Acids
Indiana University
 2025-02-28
NCT03965988 RECRUITING
Breath Holding Attack
Sherief Abd-Elsalam
 2018-05-01 PHASE3
NCT07533136 NOT_YET_RECRUITING
Uncomplicated P. Vivax Mono-infection
Walter Reed Army Institute of Research (WRAIR)
 2026-05-01
NCT07557927 NOT_YET_RECRUITING
Discoid Lupus Erythematosus
Kunming Pharmaceuticals, Inc.
 2026-04-30 PHASE2
NCT07021430 RECRUITING
Malaria Prevention
University of North Carolina, Chapel Hill
 2026-09-27 EARLY_PHASE1
NCT06962319 RECRUITING
Malaria, Pregnancy; Malaria, Antepartum; Malaria (Uncomplicated)
Liverpool School of Tropical Medicine
 2025-09-30 PHASE3
NCT07060794 NOT_YET_RECRUITING
Vivax Malaria
Menzies School of Health Research
 2026-06 PHASE4
NCT06068530 RECRUITING
Plasmodium Falciparum Malaria
University of Oxford
 2025-02-15 PHASE4
NCT02647723 ACTIVE_NOT_RECRUITING
Pregnancy; Child Development
University of Chicago
 2016-01
NCT06995586 NOT_YET_RECRUITING
Cardio-pulmonary Bypass; Cardiovascular Diseases; Omega-3 Polyunsaturated Fatty Acids; Omega-3 Supplementation; Vitamin C; Supplements; Postoperative Depression; Antioxidants; Lactulose; Postoperative; Optimal Medical Therapy; CABG; Coronary Artery Bypass Grafting; Prebiotics
Nicosia General Hospital
 2026-09-01
NCT04704999 RECRUITING
Plasmodium Vivax Malaria
University of Oxford
 2024-07-22 PHASE4
NCT06494488 RECRUITING
Lipid Metabolism Disorders; Hypertriglyceridemia
The Miriam Hospital
 2025-07-10 EARLY_PHASE1
NCT07272382 RECRUITING
Esophageal Neoplasms
Fudan University
 2025-06-05
NCT04978272 ACTIVE_NOT_RECRUITING
Malaria
Grant Dorsey, M.D, Ph.D.
 2022-02-08 PHASE3
NCT07322965 RECRUITING
Glaucoma; Primary Open Angle Glaucoma (POAG); Neuroprotection
Institut Catala de Retina
 2025-04-01
NCT05380401 RECRUITING
Premature
The University of Texas Health Science Center at San Antonio
 2023-03-09
NCT06207071 RECRUITING
Infant Malnutrition; Light-For-Dates With Signs of Fetal Malnutrition; Premature; Nutrition Disorder, Infant
University of Alabama at Birmingham
 2024-05-20
NCT06629103 ACTIVE_NOT_RECRUITING
Optimal Absorption of Omega-3; Healthy
RDC Clinical Pty Ltd
 2025-08-06 PHASE4
NCT07118059 NOT_YET_RECRUITING
Tuberculosis; Inflammation Biomarkers; Liver Function Tests; Iron Status; Metabolomics; Nutritional Status; Clinical Outcomes
North-West University, South Africa
 2025-08 PHASE2
NCT07753174 RECRUITING
Omega-3 Deficiency; DHA and EPA Blood Levels; Cardiovascular Health; Cognitive Health
Revive Active
 2026-09
NCT07403643 NOT_YET_RECRUITING
Uncomplicated Malaria
Curtin University
 2026-04 PHASE4
NCT07241377 ACTIVE_NOT_RECRUITING
Absorption of Omega-3; Omega-3 Supplementation; Healthy Participants
RDC Clinical Pty Ltd
 2025-10-27 PHASE3
NCT07271758 ENROLLING_BY_INVITATION
Nutrient Deficiency
Wake Forest University Health Sciences
 2026-04-13
NCT07389057 RECRUITING
Malaria Asymptomatic Parasitaemia; Malaria Falciparum; Malaria Infection; Malaria Transmission
Noguchi Memorial Institute for Medical Research
 2023-11-01
NCT07652684 RECRUITING
Bronchopulmonary Dysplasia (BPD)
Aristotle University Of Thessaloniki
 2025-03-04 PHASE4
NCT05949190 ACTIVE_NOT_RECRUITING
Malnutrition in Pregnancy; Preterm Birth; Child Development; Postpartum Depression; Antepartum Depression
Washington University School of Medicine
 2023-08-18
NCT07082205 ACTIVE_NOT_RECRUITING
Malaria; Severe Malaria; Severe Anaemia; Post Discharge
Liverpool School of Tropical Medicine
 2025-05-02 PHASE3
NCT06842524 RECRUITING
Polycystic Ovary Syndrome (PCOS)
Shanghai Zhongshan Hospital
 2025-04-16 PHASE2
NCT06950203 RECRUITING
Infertility, Male
Epax Norway AS
 2025-03-10
NCT06975241 RECRUITING
Healthy; Omega 3; Metabolism, Lipids
University of Toronto
 2025-07-29 PHASE4
NCT06928701 RECRUITING
Early Breast Cancer; Neoadjuvant Treatment
University of Eastern Piedmont
 2024-09-01
NCT05038462 RECRUITING
Fetal Growth Retardation; Intrauterine Growth Restriction
Institut d'Investigacions Biomèdiques August Pi i Sunyer
 2023-01-18
NCT07673185 RECRUITING
Periodontal Disease; Periodontitis (Stage 3); Smoking Behaviors
Al-Azhar University
 2025-01-15
NCT06870344 ACTIVE_NOT_RECRUITING
Malaria Infection; Malaria Falciparum
University of North Carolina, Chapel Hill
 2025-03-12
NCT07393399 NOT_YET_RECRUITING
Lupus Erythematosus, Systemic
University of Sao Paulo
 2026-07
NCT07679542 RECRUITING
MAFLD
The First Affiliated Hospital with Nanjing Medical University
 2026-03-30 PHASE1; PHASE2
NCT07346703 ENROLLING_BY_INVITATION
Multiple Sclerosis; Performance Enhancement; Supplemental Nutrition Assistance Program Education; Strength Outcomes; Function Improvement; Intervention Study
Francisco Javier Martínez Noguera
 2026-01
NCT07007078 RECRUITING
Acne Vulgaris
Shanghai Zhongshan Hospital
 2025-06 EARLY_PHASE1
NCT07012486 RECRUITING
Androgenetic Alopecia (AGA)
Shanghai Zhongshan Hospital
 2025-06 EARLY_PHASE1
NCT06981676 RECRUITING
Maternal Obesity; Obesity
Pontificia Universidad Catolica de Chile
 2023-07-25
NCT06319079 RECRUITING
Lactating Mothers; Infants
Instituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri
 2024-06-01
NCT05788094 RECRUITING
Malaria; Malaria, Vivax; Plasmodium Vivax Malaria
Shoklo Malaria Research Unit
 2023-06-26 PHASE4
NCT07634133 ENROLLING_BY_INVITATION
Healthy Volunteers
The Jerzy Kukuczka Academy of Physical Education in Katowice
 2025-04-15
NCT06187077 RECRUITING
Health Equity; Cardiovascular Diseases
Mayo Clinic
 2024-07-11
NCT05841927 ACTIVE_NOT_RECRUITING
Autism or Autistic Traits
Children's Hospital of Fudan University
 2020-12-01
NCT06347471 COMPLETED
Falciparum; Malaria
Infectious Diseases Research Collaboration, Uganda
 2024-05-28 PHASE4
NCT07771309 COMPLETED
Omega-3 Fatty Acids; Absorption of Omega-3; Pharmacokinetics
University of Copenhagen
 2025-04-15
NCT06083688 COMPLETED
Malaria,Falciparum; Anemia in Children
Liverpool School of Tropical Medicine
 2024-10-14 PHASE4
NCT06833554 RECRUITING
Gestational Diabetes Mellitus (GDM)
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
 2023-01-01
NCT07801352 ACTIVE_NOT_RECRUITING
Locally Advanced Colorectal Cancer; Metastatic Colorectal Cancer
Shanghai Changzheng Hospital
 2024-07-01 PHASE2
NCT07096466 COMPLETED
Healthy Skin
Amazentis SA
 2025-06-23
NCT06146387 COMPLETED
Cognitive Change
Heilongjiang Feihe Dairy Co. Ltd.
 2023-11-14
NCT05426434 ACTIVE_NOT_RECRUITING
Malaria; Malaria in Pregnancy; Pregnancy Related
Menzies School of Health Research
 2022-08-31 PHASE3
NCT06417099 COMPLETED
Polycystic Ovary Syndrome
Shanghai Zhongshan Hospital
 2024-05-24 PHASE2
NCT06366893 UNKNOWN
Infant, Premature, Diseases
Hospital Universitari Vall d'Hebron Research Institute
 2024-03-04
NCT06294067 COMPLETED
Nutrition, Healthy
University of Toronto
 2024-02-26 PHASE1
NCT07768423 RECRUITING
Physical Performance; Cognitive Function; Sports Nutrition
The Jerzy Kukuczka Academy of Physical Education in Katowice
 2025-01-07
NCT06516042 ACTIVE_NOT_RECRUITING
Plasmodium Falciparum; Malaria
PATH
 2024-08-21 PHASE3
NCT05950204 UNKNOWN
Acute Lymphoblastic Leukemia; Vitamin d Deficiency
Coordinación de Investigación en Salud, Mexico
 2022-09-10
NCT03576989 COMPLETED
Chronic Venous Leg Ulcers
Ohio State University
 2019-04-15
NCT03831178 ACTIVE_NOT_RECRUITING
Breast Cancer
AHS Cancer Control Alberta
 2019-08-28 PHASE2
NCT06302023 COMPLETED
Pregnant Women Diagnosed With Threatened Preterm Labor
Khon Kaen University
 2024-04-01 PHASE2
NCT06157398 COMPLETED
Healthy Individuals
University of British Columbia
 2024-01-29
NCT04496817 UNKNOWN
Diabetic Retinopathy; Type 2 Diabetes
University of Manitoba
 2022-07-11
NCT06532435 COMPLETED
Cognitive Change
Shandong Sibote Biotechnology Co., Ltd.
 2024-06-25
NCT04336189 COMPLETED
Malaria
Grant Dorsey, M.D, Ph.D.
 2020-12-28 PHASE3
NCT05191823 ACTIVE_NOT_RECRUITING
Preterm Birth; Child Development
Sarah Keim
 2021-12-01
NCT05935020 COMPLETED
Osteoarthritis, Knee
Copenhagen University Hospital, Hvidovre
 2023-08-22
NCT06840964 COMPLETED
Hypertension; Dyslipidemia
Santa Maria de la Salud, Argentina
 2023-03-23
NCT07521449 COMPLETED
Attention Deficit Hyperactivity Disorder (ADHD); ADHD
Çağlar Charles Daniel Jaicks
 2023-12-30
NCT05946642 UNKNOWN
Malaria
Malaria Consortium
 2023-07-15 PHASE3
NCT05763940 UNKNOWN
Dry Eye Syndromes; Age-Related Macular Degeneration; Omega 3 Index
Western University of Health Sciences
 2022-05-25
NCT03613844 COMPLETED
Brain DHA Delivery and Alzheimer's Disease Risk
University of Southern California
 2018-09-01 PHASE2
NCT06274788 Not yet recruiting
Parenteral Nutrition Associated Liver Disease (PNALD)|Essential Fatty Acid Deficiency|Malnutrition|Pediatric ALL
Fresenius Kabi
 2024-05-01 Phase 4
NCT04460287 COMPLETED
Healthy Children
Indonesian Nutrition Association
 2023-02-17
NCT06319079 Not yet recruiting
Lactating Mothers|Infants
Instituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri
 2024-03 Not Applicable
NCT05294406 COMPLETED
Malaria in Pregnancy
Liverpool School of Tropical Medicine
 2022-02-07 PHASE4
NCT04767217 COMPLETED
Uncomplicated Malaria
Jhpiego
 2021-06-14 PHASE4
NCT05915806 ACTIVE_NOT_RECRUITING
Bronchopulmonary Dysplasia; Child Development; Neonatal and Perinatal Conditions
CHU de Quebec-Universite Laval
 2023-07-30
NCT05953064 ACTIVE_NOT_RECRUITING
Hypertriglyceridemia
University Hospital, Gentofte, Copenhagen
 2023-01-01
NCT05343312 COMPLETED
Malaria
Centro de Investigacao em Saude de Manhica
 2022-03-16 PHASE4
NCT05980156 COMPLETED
Malaria,Falciparum; Anemia in Children
University of Maryland, Baltimore
 2023-02-13 PHASE4
NCT06254040 COMPLETED
Mild Cognitive Impairment
Biosearch S.A.
 2022-07-01
NCT04844099 COMPLETED
Sickle Cell Anemia in Children; Malaria
Liverpool School of Tropical Medicine
 2021-04-09 PHASE3
NCT04816461 COMPLETED
Malaria; Malaria Prophylaxis; Mass Testing and Treatment
Institut de Recherche en Sciences de la Sante, Burkina Faso
 2021-07-07 PHASE4
NCT05252845 COMPLETED
Malaria,Falciparum
University of Oxford
 2023-01-04 PHASE2
NCT07304921 COMPLETED
Lipid Metabolism; Omega-3 Polyunsaturated Fatty Acids; Supplementation
Riga Stradins University
 2023-04-06 PHASE1
NCT05121766 TERMINATED
COVID-19
Hackensack Meridian Health
 2022-01-10 PHASE1
NCT05465135 COMPLETED
Polycystic Ovary Syndrome
Shanghai Zhongshan Hospital
 2022-07-01 PHASE4
NCT04844905 UNKNOWN
Malaria,Falciparum; Neglected Tropical Diseases; Strongyloidiasis; Lymphatic Filariasis; Scabies; Hook Worm; Soil Transmitted Helminths
London School of Hygiene and Tropical Medicine
 2021-05-03 PHASE3
NCT05266677 WITHDRAWN
Infants; Toddlers; Nutritional Supplement
Société des Produits Nestlé (SPN)
 2022-07
NCT05340153 UNKNOWN
Malaria
University of Yaounde 1
 2022-04-11 PHASE4
NCT04864444 COMPLETED
Malaria,Falciparum; Malaria
University of California, San Francisco
 2021-06-19
NCT05829187 COMPLETED
Uncomplicated Plasmodium Falciparum
Syamsudin Abdillah,Ph.D, Pharm D
 2022-11-01 PHASE2
NCT04149106 UNKNOWN
Malaria,Falciparum
University Clinical Research Center, Mali
 2019-07-01 PHASE3
NCT04767191 COMPLETED
Uncomplicated Malaria
Jhpiego
 2021-03-15 PHASE4
NCT03972319 UNKNOWN
Fatty Liver; Bariatric Surgery Candidate
Khoo Teck Puat Hospital
 2019-09-17 EARLY_PHASE1
NCT05323721 UNKNOWN
Malaria
Malaria Consortium
 2022-06-01 PHASE4
NCT04189744 COMPLETED
Pregnancy Malaria; Bacterial Vaginoses; Trichomonas Vaginitis
London School of Hygiene and Tropical Medicine
 2019-12-15 PHASE3
NCT05438173 COMPLETED
Bioavailability
Midwest Center for Metabolic and Cardiovascular Research
 2022-07-11
NCT04198805 COMPLETED
Non-Alcoholic Fatty Liver Disease; Non-Alcoholic Fatty Liver; Non-Alcoholic Steatohepatitis
Naga P. Chalasani
 2020-01-03 PHASE2
NCT03851120 COMPLETED
Maternal Exposure; Health Behavior; Infant Development; Child Development
Indonesia University
 2019-10-31 PHASE2
NCT05244954 COMPLETED
Malaria,Falciparum; Anemia in Children
University of Maryland, Baltimore
 2022-02-01 PHASE4
NCT03671109 COMPLETED
Malaria; HIV/AIDS; Pregnancy Related
Barcelona Institute for Global Health
 2019-09-18 PHASE3
NCT04661579 COMPLETED
Plasmodium Falciparum
PATH
 2020-11-06 PHASE2
NCT05527106 COMPLETED
Glaucoma
Institut Catala de Retina
 2015-03-12
NCT04158713 COMPLETED
Pregnancy; HIV; Malaria
Liverpool School of Tropical Medicine
 2019-11-11 PHASE3
NCT04487145 COMPLETED
Drug-Drug Interaction; HIV Infection
University of California, San Francisco
 2020-11-23 PHASE4
NCT03040856 WITHDRAWN
Omega 3 Supplements During Pregnancy
Sheba Medical Center
 2022-02-01
NCT05756062 COMPLETED
Keratoconus
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
 2019-02-01
NCT04828538 WITHDRAWN
Covid19
Hospital de la Soledad
 2021-01-01
NCT04743050 UNKNOWN
Fatty Acids; Alpha-Linolenic Acid; Docosahexaenoic Acids; Eicosapentaenoic Acid; Preventive Health Services; Preventive Medicine; Cardiovascular Diseases; Anti-Inflammatory Agents
Wroclaw Medical University
 2020-12-09 PHASE3
NCT05335863 COMPLETED
Healthy
Instituto de Investigación Hospital Universitario La Paz
 2021-11-03
NCT03396393 UNKNOWN
Systemic Lupus Erythematosus
Kunming Pharmaceuticals, Inc.
 2018-03 PHASE2
NCT05068557 UNKNOWN
Obesity; Chronic Inflammation
University of Guadalajara
 2021-09-24
NCT04147546 COMPLETED
Plasmodium Falciparum Malaria; Malaria Diagnosis
Institut de Recherche en Sciences de la Sante, Burkina Faso
 2020-08-31 PHASE3
NCT03345550 TERMINATED
Mild Traumatic Brain Injury
University of Michigan
 2017-09-12 PHASE2
NCT04278482 COMPLETED
Vegetarian Diet
National Research Council, Spain
 2020-03-10
NCT03208907 COMPLETED
Malaria, Vivax; Therapeutics
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
 2018-07-05 PHASE3
NCT05874869 COMPLETED
Malaria; Chemoprophylaxis; Underfive Children
Richard Mwaiswelo
 2020-07-01
NCT05427604 COMPLETED
Healthy
Université Catholique de Louvain
 2021-02-23
NCT04660110 UNKNOWN
Malaria
Makerere University
 2021-01-28 PHASE3
NCT04245033 COMPLETED
Malaria
National Institute for Medical Research, Tanzania
 2020-07-20 PHASE4
NCT04151758 UNKNOWN
Childhood Obesity
University of Milan
 2019-01-07 PHASE4
NCT04477395 COMPLETED
Periodontitis; Therapeutics; Fatty Acids, Unsaturated
Medical University of Lodz
 2017-11-01
NCT04159532 COMPLETED
Healthy Adults
SCF Pharma
 2019-12-18 PHASE4
NCT03640403 COMPLETED
Malaria,Falciparum; Anemia
National Institute for Medical Research, Tanzania
 2019-03-26 PHASE3
NCT04570995 TERMINATED
Brain Health; Brain Function; Brain Development
Wake Forest University Health Sciences
 2020-11-05
NCT03178643 COMPLETED
Malaria,Falciparum
Duke University
 2018-01-23 PHASE4
NCT04609098 COMPLETED
Malaria, Falciparum
London School of Hygiene and Tropical Medicine
 2020-10-29 PHASE2
NCT04069195 UNKNOWN
Inflammation; Pregnancy Related
Walter Reed National Military Medical Center
 2019-02-01
NCT04746885 COMPLETED
Neonatal Disease
Ain Shams University
 2017-09-21
NCT02626299 COMPLETED
Preterm Birth
University of Kansas Medical Center
 2016-06-08 PHASE3
NCT04009343 ACTIVE_NOT_RECRUITING
Uncomplicated Falciparum Malaria
Johns Hopkins Bloomberg School of Public Health
 2019-06-19 PHASE2; PHASE3
NCT02709239 COMPLETED
Use and Dose of Prenatal DHA Supplementation
University of Kansas Medical Center
 2016-06-01
NCT04160026 COMPLETED
Malaria in Pregnancy; Adherence, Treatment
Liverpool School of Tropical Medicine
 2019-11-11 PHASE4
NCT05219890 WITHDRAWN
Obesity; Inflammation; Immune System Disorder
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
 2017-01-16
NCT02670382 COMPLETED
Metabolic Syndrome
Tufts University
 2016-03
NCT03583281 COMPLETED
Obesity; Inflammation
University of Manitoba
 2018-06-01
NCT03796455 COMPLETED
Chronic Obstructive Pulmonary Disease
Texas A&M University
 2018-04-25
NCT03691519 COMPLETED
Alzheimer Disease
University Hospital, Toulouse
 2018-04-17 PHASE3
NCT03208179 COMPLETED
Pregnancy; Malaria in Pregnancy; Malaria
Liverpool School of Tropical Medicine
 2018-03-29 PHASE3
NCT04242004 UNKNOWN
Neurocognitive Impairment
Fudan University
 2019-10-30 PHASE1; PHASE2
NCT04987567 COMPLETED
Cystic Fibrosis in Children
Corporacion Parc Tauli
 2018-03-21
NCT04796207 COMPLETED
Traumatic Brain Injury (TBI); Chronic Traumatic Encephalopathy (CTE)
University of Arizona
 2019-05-28
NCT04496154 COMPLETED
Type 2 Diabetes; Insulin Sensitivity/Resistance; Inflammatory Response; Fatty Acids, Omega-3
May Faraj, PDt, PhD
 2013-09-05
NCT04049916 COMPLETED
Malaria,Falciparum
London School of Hygiene and Tropical Medicine
 2019-09-12 PHASE2; PHASE3
NCT02909712 COMPLETED
Malaria; Pregnancy Malaria; Cardiotoxicity; Cardiac Safety; Parasitemia
London School of Hygiene and Tropical Medicine
 2016-09 PHASE2
NCT03576313 COMPLETED
Malaria
London School of Hygiene and Tropical Medicine
 2018-08-11 PHASE3
NCT04438928 COMPLETED
Healthy Pregnant Women
Bayer
 2016-09-27
NCT02271230 COMPLETED
Heart Failure
Brigham and Women's Hospital
 2014-08 PHASE3
NCT04462939 COMPLETED
Healthy Lactating Mother
Bayer
 2017-04-26
NCT03739463 UNKNOWN
PPROM
Université de Sherbrooke
 2018-12-03
NCT03926351 UNKNOWN
Dementia; Inflammation; Mild Cognitive Impairment; Cognitive Decline; SCD; Cognitive Dysfunction; Pathologic Processes; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorder; Cognition Disorders
University Hospital, Akershus
 2018-10-01 PHASE2
NCT03598413 COMPLETED
Colorectal Cancer; Nutritional Deficiency; Infected Wound; Surgical Site Infection; Complication, Postoperative; Surgery; Surgery--Complications; Sarcopenia; Phagocytic Dysfunction
Royal Surrey County Hospital NHS Foundation Trust
 2018-07-16
NCT03808207 UNKNOWN
Breastfeeding; Human Milk; Diet Habit; Fatty Acid; Infant Growth
Università degli Studi di Ferrara
 2018-08-06
NCT02802501 COMPLETED
Malaria, Vivax
GlaxoSmithKline
 2018-04-08 PHASE3
NCT03735836 COMPLETED
Pharmacokinetic in Normal Population
Samuel Fortin
 2018-08-08 PHASE4
NCT02514070 COMPLETED
Lipoprotein Metabolism; PCSK9; Proteomics
National Heart, Lung, and Blood Institute (NHLBI)
 2015-10-30 PHASE2
NCT03300388 COMPLETED
Obesity; Aging; Inflammation
Clinica Universidad de Navarra, Universidad de Navarra
 2017-08-21
NCT03402464 UNKNOWN
EGFR Positive Non-Small Cell Lung Cancer,Adenocarcinoma
Peking University Cancer Hospital & Institute
 2018-01 PHASE2
NCT03742492 UNKNOWN
Healthy Volunteers
Universidade do Porto
 2018-09-19 PHASE2
NCT03014115 COMPLETED
Healthy Infants
dsm-firmenich Switzerland AG
 2016-11
NCT02371460 TERMINATED
Bronchopulmonary Dysplasia; Child Development; Neonatal and Perinatal Conditions
CHU de Quebec-Universite Laval
 2015-06-23 PHASE3
NCT06036030 COMPLETED
Malaria,Falciparum; Malaria, Vivax; Malaria; Infections; Uncomplicated Malaria; Uncomplicated Plasmodium Falciparum
Syamsudin Abdillah,Ph.D, Pharm D
 2019-01-11 PHASE2
NCT03072277 COMPLETED
Pregnancy
Public Health Foundation of India
 2015-12 PHASE3
NCT02721420 UNKNOWN
Malaria; Severe Anemia
Kamuzu University of Health Sciences
 2016-03-24 PHASE3
NCT02705430 UNKNOWN
Type 2 Diabetes
Rabin Medical Center
 2018-06-20
NCT03697668 UNKNOWN
Plasmodium Falciparum Malaria (Drug Resistant)
Nurex S.r.l.
 2017-09-17 PHASE2
NCT02878200 COMPLETED
Malaria
London School of Hygiene and Tropical Medicine
 2016-11-04
NCT02793622 COMPLETED
Malaria
University of California, San Francisco
 2016-09 PHASE3
NCT02763514 COMPLETED
Cognitive Function
Northumbria University
 2016-10
NCT03592251 COMPLETED
Memory Consolidation
Northumbria University
 2017-08-01
NCT02671175 COMPLETED
Malaria; Severe Anemia
Liverpool School of Tropical Medicine
 2016-05-20 PHASE3
NCT03009526 COMPLETED
Malaria; Pregnancy
Kamuzu University of Health Sciences
 2017-01-17 PHASE3
NCT02612545 COMPLETED
Acute Falciparum Malaria
National Institute of Allergy and Infectious Diseases (NIAID)
 2015-11-20 PHASE1
NCT02947100 TERMINATED
Sickle Cell Disease
Robin E. Miller
 2018-01-25 PHASE1; PHASE2
NCT03569501 UNKNOWN
Gestational Diabetes Mellitus in Pregnancy
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
 2017-08-01
NCT03582267 COMPLETED
Head Trauma
Texas Christian University
 2017-08-01
NCT03192839 COMPLETED
Prematurity
Mead Johnson Nutrition
 2017-07-01
NCT04128449 COMPLETED
Performance
Universidad Católica San Antonio de Murcia
 2018-04-01
NCT02802813 COMPLETED
Plasmodium Vivax
University of Oxford
 2016-06-14 PHASE1; PHASE2
NCT02163447 COMPLETED
Malaria
Grant Dorsey, M.D, Ph.D.
 2014-06-23 PHASE3
NCT04972643 COMPLETED
Alzheimer Disease; Dementia Disorder
Taichung Veterans General Hospital
 2012-09-23
NCT03443076 COMPLETED
Bioavailability
Midwest Center for Metabolic and Cardiovascular Research
 2018-02-16
NCT02336243 UNKNOWN
Premature Birth; Preeclampsia; Fetal Growth Retardation; Stillbirth
Pontificia Universidad Catolica de Chile
 2015-05 PHASE3
NCT03559361 COMPLETED
Sleep
Northumbria University
 2017-03-01
NCT02992119 COMPLETED
Malaria Vaccine
University of Oxford
 2017-06-04 PHASE2
NCT02940756 COMPLETED
Malaria
Ministry of Public Health, Democratic Republic of the Congo
 2017-03-15 PHASE4
NCT00420602 COMPLETED
Dominantly Inherited Stargardt's Disease (STGD3)
University of Utah
 2007-09-21
NCT03431714 COMPLETED
Uncomplicated Falciparum Malaria
National Institute for Medical Research, Tanzania
 2017-07-14 PHASE4
NCT02914145 COMPLETED
Malaria
Centro de Investigacao em Saude de Manhica
 2015-11
NCT03961763 COMPLETED
Cardiovascular Diseases; Hyperlipidemias; Dyslipidemias
University of Chester
 2017-06-01
NCT02472171 COMPLETED
Inflammation
USDA, Western Human Nutrition Research Center
 2015-06
NCT02509728 COMPLETED
Infant, Premature
University Hospital Tuebingen
 2015-07
NCT04897919 COMPLETED
Malaria; Effectiveness
Bandim Health Project
 2015-08-01 PHASE4
NCT04210804 COMPLETED
Bipolar Depression
National University of Ireland, Galway, Ireland
 2014-04-01 PHASE2
NCT01745510 COMPLETED
Necrotizing Enterocolitis
Coordinación de Investigación en Salud, Mexico
 2012-10 PHASE1; PHASE2
NCT03158545 COMPLETED
Neurovascular Coupling
Northumbria University
 2016-10-10
NCT02517502 COMPLETED
Cognitive Dysfunction
Carol Fabian, MD
 2015-07 EARLY_PHASE1
NCT01903525 COMPLETED
Concussion; Mild Traumatic Brain Injury
University of Texas Southwestern Medical Center
 2013-09 PHASE1
NCT01956188 UNKNOWN
Systemic Lupus Erythematosus; Primary Antiphospholipid Syndrome
University of Sao Paulo
 2014-05
NCT02315690 COMPLETED
Malaria
University of California, San Francisco
 2015-09 PHASE3
NCT02461186 WITHDRAWN
Uncomplicated Falciparum Malaria; Artemisinin-resistant
University of Oxford
 2015-06 PHASE2; PHASE3
NCT03378232 COMPLETED
Cardiovascular Disease
University of Guelph
 2017-01-05
NCT01576783 COMPLETED
Preterm Birth; Child Development
Sarah Keim
 2012-04-26 PHASE4
NCT05060198 COMPLETED
Malaria,Falciparum
Kenya Medical Research Institute
 2016-06-17
NCT01883817 COMPLETED
Attention Deficit Disorder
University of Cincinnati
 2013-09 PHASE3
NCT01640587 TERMINATED
P. Falciparum Malaria
University of Oxford
 2013-11
NCT02831023 COMPLETED
Malaria
University of California, San Francisco
 2016-07 PHASE2
NCT01826422 COMPLETED
Muscular Dystrophy, Duchenne
Coordinación de Investigación en Salud, Mexico
 2013-03
NCT03317171 COMPLETED
Muscular Dystrophies; Muscle Inflammation
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
 2016-02-28
NCT01845610 COMPLETED
Malnutrition
North-West University, South Africa
 2013-09
NCT01580345 COMPLETED
Pregnancy
Centre for Chronic Disease Control, India
 2015-12 PHASE3
NCT02614404 COMPLETED
Plasmodium Falciparum Malaria
HuLow
 2015-11 PHASE1
NCT02568098 COMPLETED
Drug Combination; Pharmacokinetics; Healthy
University of Oxford
 2015-10 PHASE1
NCT03017651 COMPLETED
Overweight and Obesity
Société des Produits Nestlé (SPN)
 2016-11 PHASE1
NCT02788864 COMPLETED
Malaria
Oxford University Clinical Research Unit, Vietnam
 2016-05-20 PHASE4
NCT02661698 COMPLETED
Lipid Absorption and Metabolism
Northumbria University
 2016-02
NCT02654730 TERMINATED
Malaria
London School of Hygiene and Tropical Medicine
 2015-12 PHASE2; PHASE3
NCT01054248 COMPLETED
Malaria
University of Oxford
 2010-02-16 PHASE3
NCT02604966 UNKNOWN
Drug Resistant Malaria Due to Plasmodium Falciparum
National Institute of Malariology, Parasitology and Entomology, Vietnam
 2015-04 PHASE4
NCT02653898 UNKNOWN
Malaria; Parasitic Diseases
Armed Forces Research Institute of Medical Sciences, Thailand
 2016-01 PHASE4
NCT01051154 COMPLETED
Acute Lymphoblastic Leukemia; Malnutrition
Coordinación de Investigación en Salud, Mexico
 2010-09 PHASE2
NCT02511353 COMPLETED
Malaria
Liverpool School of Tropical Medicine
 2015-07 PHASE2
NCT02434952 COMPLETED
Malaria, Falciparum; G6PD Deficiency
Malaria Consortium
 2014-10 PHASE4
NCT00982462 COMPLETED
Infant Development
Retina Foundation of the Southwest
 2011-01-20
NCT02637778 COMPLETED
Cardiovascular Diseases
University of Jena
 2016-02
NCT02329301 COMPLETED
Malaria; Malaria, Falciparum
PATH
 2014-09
NCT01563913 COMPLETED
Parkinson's Disease
VA Office of Research and Development
 2012-10 PHASE1
NCT02282293 COMPLETED
Malaria; Human Immunodeficiency Virus
University of California, San Francisco
 2014-12-09 PHASE3
NCT02057406 COMPLETED
Depression
Wei Jiang
 2014-05 PHASE3
NCT02487771 COMPLETED
Pregnancy
Susan Carlson, PhD
 2008-07 PHASE3
NCT02001428 COMPLETED
Plasmodium Falciparum Malaria; Plasmodium Vivax Malaria
Gadjah Mada University
 2014-07-21
NCT02518672 TERMINATED
Cystic Fibrosis
SCF Pharma
 2015-10 PHASE2
NCT01849250 COMPLETED
Benign Breast Neoplasm; Ductal Breast Carcinoma In Situ; Invasive Breast Carcinoma; Lobular Breast Carcinoma In Situ; Paget Disease of the Breast; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage IIA Breast Cancer; Stage IIB Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer
National Cancer Institute (NCI)
 2013-05 PHASE2
NCT02605720 COMPLETED
Malaria
Lihir Medical Centre
 2015-09 PHASE3
NCT03620097 COMPLETED
ASD
Maimónides Biomedical Research Institute of Córdoba
 2015-01-21
NCT02590627 COMPLETED
Malaria
National Institute for Medical Research, Tanzania
 2014-05 PHASE4
NCT02091583 COMPLETED
Metabolic Syndrome
University of Manitoba
 2014-11
NCT01704508 COMPLETED
Malaria
Bandim Health Project
 2012-11 PHASE4
NCT03109626 COMPLETED
SCA38
Barbara Borroni
 2015-06-17
NCT02192944 COMPLETED
Healthy
University of Oxford
 2014-07 PHASE4
NCT02259426 COMPLETED
Malaria; Asymptomatic Malaria; Plasmodium Falciparum
London School of Hygiene and Tropical Medicine
 2014-10 PHASE3
NCT02195609 COMPLETED
Menopause; Hot Flashes
Instituto Palacios
 2014-03 PHASE4
NCT02987270 COMPLETED
Malaria,Falciparum
Simon Kariuki
 2013-04 PHASE3
NCT02359045 COMPLETED
Relative Bioavailability; AUC; Cmax; Pharmacokinetics
AstraZeneca
 2015-02-12 PHASE1
NCT03956433 COMPLETED
Metabolic Syndrome
University of Leeds
 2014-09-01
NCT01640574 COMPLETED
Vivax Malaria
University of Oxford
 2012-02 PHASE3
NCT02144402 COMPLETED
Growth; Tolerance; Infant Development
dsm-firmenich Switzerland AG
 2014-05
NCT01810003 COMPLETED
Cardiovascular Disease, Inflammation
Laval University
 2013-03
NCT01887821 COMPLETED
Plasmodium Vivax Malaria
Oxford University Clinical Research Unit, Vietnam
 2013-02 PHASE4
NCT02325180 COMPLETED
Malaria, Falciparum
London School of Hygiene and Tropical Medicine
 2015-01 PHASE4
NCT02889341 COMPLETED
Male Infertility
Vida Recoletas Sevilla
 2013-10-22
NCT02372344 COMPLETED
Healthy
AstraZeneca
 2015-03 PHASE1
NCT01389427 COMPLETED
Mantle Cell Lymphoma Refractory
The Lymphoma Academic Research Organisation
 2011-11 PHASE1; PHASE2
NCT02098317 COMPLETED
NAFLD; Non Alcoholic Steatohepatitis (NASH)
Bambino Gesù Hospital and Research Institute
 2014-01 PHASE3
NCT02308930 UNKNOWN
Healthy
Sun Yat-sen University
 2014-07
NCT02324738 COMPLETED
Healthy
University of Oxford
 2015-01 PHASE4
NCT02184637 COMPLETED
Malaria, Vivax
GlaxoSmithKline
 2014-07-31 PHASE1
NCT02009215 COMPLETED
Malaria
London School of Hygiene and Tropical Medicine
 2014-02 PHASE4
NCT02168738 COMPLETED
Healthy Subject
Hospices Civils de Lyon
 2014-03
NCT01955044 COMPLETED
Premature, Extremely Low Birth Weight Infants; Polyunsaturated Fatty Acid Levels
Endeavor Health
 2013-09
NCT01828944 COMPLETED
Osteopenia; Sarcopenia
Lesieur
 2012-12
NCT02132663 COMPLETED
Growth of Term Infants
Mead Johnson Nutrition
 2014-05
NCT02128984 COMPLETED
Cystic Fibrosis; Failure to Thrive; Malnutrition
Laboratorios Ordesa
 2012-01
NCT01796262 COMPLETED
Attention Deficit Hyperactivity Disorder
IRCCS Eugenio Medea
 2012-06 PHASE3
NCT01838902 COMPLETED
Malaria
London School of Hygiene and Tropical Medicine
 2013-08 PHASE3
NCT01846325 COMPLETED
Asthenozoospermia
National Nutrition and Food Technology Institute
 2013-12 PHASE2; PHASE3
NCT02615405 COMPLETED
Major Depressive Disorder
National Science and Technology Council, Taiwan
 2012-08
NCT01743820 COMPLETED
Malaria
University of California, San Francisco
 2013-09 PHASE2
NCT01865448 COMPLETED
Obesity; Inflammation
Protein Supplies SL
 2013-05
NCT01849640 SUSPENDED
Uncomplicated Plasmodium Falciparum Malaria
David Saunders
 2012-12
NCT02118090 COMPLETED
Vivax Malaria
Institut Pasteur, Cambodia
 2014-05 PHASE4
NCT01997268 WITHDRAWN
Severe Hypertriglyceridemia
Sancilio and Company, Inc.
 PHASE3
NCT01504633 UNKNOWN
Cognitive Ability, General
Indonesia University
 2011-12
NCT01936194 WITHDRAWN
Atopic Dermatitis
Mead Johnson Nutrition
 2013-09
NCT01755559 COMPLETED
Malaria
Epicentre
 2013-06 PHASE4
NCT01669941 COMPLETED
Pregnancy; Malaria
Kenya Medical Research Institute
 2012-08 PHASE4
NCT01934777 COMPLETED
Fatty Liver; Liver Fibrosis; Obesity; Metabolic Syndrome; Nonalcoholic Fatty Liver Disease
Bambino Gesù Hospital and Research Institute
 2013-10 PHASE3
NCT03364699 COMPLETED
Immune Dysfunction
University of Sao Paulo
 2013-03
NCT00760760 COMPLETED
Adipose Tissue Inflammation; Morbid Obesity
Medical University of Vienna
 2008-09 PHASE2
NCT01624337 TERMINATED
Malaria
Armed Forces Research Institute of Medical Sciences, Thailand
 2012-05
NCT01930331 COMPLETED
Plasmodium Falciparum; Malaria, Falciparum
Ifakara Health Institute
 2014-01-07 PHASE4
NCT01899820 UNKNOWN
Malaria
Sabah Ahmed Omar
 2013-04 PHASE3
NCT01548534 TERMINATED
Metastatic Breast Cancer; Progesterone Receptor Positive Tumor; Estrogen Receptor Positive Tumor; HER-2 Negative Tumor
University Hospital, Tours
 2012-02 PHASE3
NCT01845701 COMPLETED
Malaria
University of Yaounde 1
 2010-03 PHASE3
NCT00948896 COMPLETED
Malaria
University of California, San Francisco
 2010-06 PHASE3
NCT01897948 TERMINATED
Measurement of Docosahexaenoic Acid Levels in Pre-school Children
Mead Johnson Nutrition
 2013-07
NCT01908907 COMPLETED
Prematurity
Sanford Health
 2012-10
NCT01690312 COMPLETED
Cardiovascular Disease
Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
 2012-09
NCT01908374 UNKNOWN
Hypertriglyceridemia
Arctic Nutrition AS
 2013-07
NCT01470768 WITHDRAWN
Cow's Milk Allergy; Intolerance to Extensively Hydrolyzed Formulas; Intolerance to Breast Milk
Mead Johnson Nutrition
 2012-01
NCT01274910 UNKNOWN
Rheumatoid Arthritis
Rabin Medical Center
 2011-01
NCT01940679 COMPLETED
Bioavailability of Omega-3s in Military Rations
United States Army Research Institute of Environmental Medicine
 2013-09
NCT01878357 COMPLETED
Malaria
Indonesia University
 2013-06 PHASE4
NCT02859129 COMPLETED
Hypertriglyceridemia
AstraZeneca
 2013-09 PHASE1
NCT01737099 COMPLETED
Hypertriglyceridemia
dsm-firmenich Switzerland AG
 2012-11
NCT01692431 COMPLETED
Cardiovascular Physiological Phenomena; Endothelial Nitric Oxide Synthase; Eicosapentaenoic Acid; Docosahexaenoic Acid (All-Z Isomer)
University of East Anglia
 2012-09
NCT00852423 COMPLETED
Malaria in Pregnancy
Institute of Tropical Medicine, Belgium
 2010-06 PHASE3
NCT01940640 COMPLETED
Oxidative Stress
Universidad de Granada
 2012-01 PHASE2; PHASE3
NCT01611649 COMPLETED
Infant Development
Lactalis
 2012-03 PHASE2
NCT01284660 COMPLETED
HEAVY TOBACCO SMOKERS
Hillel Yaffe Medical Center
 2011-11
NCT02005900 COMPLETED
HIV-associated Hypertriglyceridemia; HIV-associated Hypercholesterolemia; HIV-associated Inflammatory State
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
 2011-06 PHASE3
NCT02036307 TERMINATED
Hypertriglyceridemia
Johns Hopkins University
 2013-04 PHASE2
NCT02974348 COMPLETED
Drug Resistant Malaria Due to Plasmodium Falciparum
University of Bamenda
 2013-01 PHASE3
NCT01127867 COMPLETED
Breast Cancer; Obesity
Rockefeller University
 2010-05
NCT00527800 COMPLETED
Malaria; HIV Infections
University of California, San Francisco
 2007-08 PHASE3
NCT01150292 COMPLETED
Type 2 Diabetes
Hospices Civils de Lyon
 2010-05
NCT00361374 COMPLETED
Major Depressive Disorder
Massachusetts General Hospital
 2006-07 PHASE3
NCT00646360 COMPLETED
Pregnancy
Emory University
 2005-02
NCT01775592 COMPLETED
Plasmodium Falciparum
National Institute of Malariology, Parasitology and Entomology, Vietnam
 2012-09 PHASE4
NCT01554462 COMPLETED
Attention Deficit Hyperactivity Disorder; Healthy
Unilever R&D
 2009-01
NCT01231113 COMPLETED
Pregnancy Complicated by Malaria as Antepartum Condition
Kwame Nkrumah University of Science and Technology
 2011-07 PHASE3
NCT01480687 UNKNOWN
Hypertension; Hypertriglyceridemia
Hospital Universitario Pedro Ernesto
 2011-05 PHASE4
NCT01651416 COMPLETED
Malaria; Anaemia
Centre for Global Health Research, Ghana
 2012-07 PHASE4
NCT01078909 COMPLETED
Cardiovascular Disease; Inflammation
Penn State University
 2011-10 PHASE3
NCT01670773 COMPLETED
Assessment of Mechanistic Blood Biomarkers in Healthy Humans
Catabasis Pharmaceuticals
 2012-08 PHASE1
NCT00345176 COMPLETED
Age-related Macular Degeneration; Cataract
National Eye Institute (NEI)
 2006-09 PHASE3
NCT01525511 COMPLETED
Healthy
University of Oxford
 2012-06 PHASE1
NCT01231880 COMPLETED
Malaria
Makerere University
 2011-02 PHASE3
NCT00711971 COMPLETED
Depression
University of Michigan
 2008-09 PHASE2; PHASE3
NCT01062373 TERMINATED
Premature
Institut National de la Santé Et de la Recherche Médicale, France
 2010-02
NCT01326754 COMPLETED
Malaria, Falciparum
Centers for Disease Control and Prevention
 2011-08
NCT01185379 COMPLETED
Cognitive Function; Mood; Well-being; Cerebral Blood Flow
Northumbria University
 2010-07
NCT01241474 COMPLETED
Metabolic Syndrome X; Type 2 Diabetes Mellitus; Sarcopenia
University of Aberdeen
 2009-02
NCT00325013 COMPLETED
Primary Sclerosing Cholangitis; Colitis
Beth Israel Deaconess Medical Center
 2005-12 PHASE1
NCT00100230 COMPLETED
Retinitis Pigmentosa; X-linked Genetic Diseases
Retina Foundation of the Southwest
 2004-09 PHASE2
NCT01544855 COMPLETED
Healthy
Université de Sherbrooke
 2011-02
NCT01288820 COMPLETED
Vivax Malaria
University of Oxford
 2011-01 PHASE3
NCT01233778 COMPLETED
Cardiovascular Disease
Penn State University
 2010-10
NCT01351012 COMPLETED
Metabolic Syndrome
University of Manitoba
 2010-09
NCT01202812 UNKNOWN
Sickle Cell Disease; HEMOGLOBIN SS; Hemoglobin S Beta-0 Thalassemia; Inflammation; Quality of Life
Thomas Jefferson University
 2010-10 PHASE2
NCT01399216 COMPLETED
Low Basal Body Temperature
Hiroshima University
 2011-07
NCT00620672 COMPLETED
Pregnancy
University of British Columbia
 2004-05 PHASE1
NCT01389557 COMPLETED
Malaria
Indonesia University
 2011-02 PHASE4
NCT00266825 COMPLETED
Pregnancy
Susan Carlson, PhD
 2006-01 PHASE3
NCT00530244 COMPLETED
Cystic Fibrosis
University of Massachusetts, Worcester
 2003-03
NCT01431690 COMPLETED
Hypertriglyceridemia
AstraZeneca
 2011-08 PHASE1
NCT00865683 UNKNOWN
Overweight and Obesity; Insulin Resistance; Diabetes, Gestational; Hypertension in Pregnancy; Pre-Eclampsia
National Heart, Lung, and Blood Institute (NHLBI)
 2009-04 PHASE1
NCT01558193 COMPLETED
Aggression
Swansea University
 2011-03
NCT01400490 UNKNOWN
Heart Disease
Cardiovascular Research Associates
 2010-09
NCT01066182 COMPLETED
Learning; Behaviour
University of Oxford
 2009-01 PHASE2
NCT01082705 COMPLETED
P. Falciparum Malaria
Centers for Disease Control and Prevention
 2010-04 PHASE3
NCT02426554 COMPLETED
Children
University of Copenhagen
 2011-01
NCT00871377 COMPLETED
Epilepsy
National Center for Complementary and Integrative Health (NCCIH)
 2008-05 PHASE2
NCT01007110 COMPLETED
Pregnancy
University of Kansas
 2009-05 PHASE3
NCT01165372 COMPLETED
Malaria
Oxford University Clinical Research Unit, Vietnam
 2010-08 PHASE2
NCT05415293 TERMINATED
Randomized Clinical Trial; Docosahexaenoic Acid; Pregnancy
University of New Mexico
 2011-05
NCT01280162 COMPLETED
Malaria
Armed Forces Research Institute of Medical Sciences, Thailand
 2010-09
NCT01192269 COMPLETED
Healthy
Ludwig-Maximilians - University of Munich
 2010-08
NCT01216982 UNKNOWN
Mood Disorders; Depression; Combat Disorders; Stress Disorders
United States Department of Defense
 2010-11 PHASE2
NCT00517036 COMPLETED
Depression
Cedars-Sinai Medical Center
 2006-07 PHASE3
NCT01200446 COMPLETED
Asthma
Indiana University
 2010-10
NCT01368484 COMPLETED
SPERM
Instituto Valenciano de Infertilidad, IVI VALENCIA
 2009-12
NCT01092377 COMPLETED
Iron Deficiency; Anemia
North-West University, South Africa
 2010-02
NCT01222949 COMPLETED
Malaria, Falciparum
sigma-tau i.f.r. S.p.A.
 2010-02 PHASE1
NCT01028274 COMPLETED
LDL Cholesterol; Triglycerides
Nordic Pharma, USA
 2009-09 PHASE1; PHASE2
NCT00868465 COMPLETED
Uncomplicated Malaria
Radboud University Medical Center
 2009-04
NCT01222962 COMPLETED
Malaria, Falciparum
sigma-tau i.f.r. S.p.A.
 2010-03 PHASE1
NCT01048970 UNKNOWN
Lung Cancer
National Institute of Cancerología
 2009-10 PHASE2; PHASE3
NCT01735357 COMPLETED
Healthy
King's College London
 2009-06
NCT00885313 COMPLETED
Fatty Liver; Liver Fibrosis; Obesity; Metabolic Syndrome; Nonalcoholic Fatty Liver Disease
Bambino Gesù Hospital and Research Institute
 2009-03 PHASE1; PHASE2
NCT01075945 UNKNOWN
Malaria
University of Khartoum
 2010-02 PHASE4
NCT01947426 COMPLETED
Oxidative Stress; Inflammation; Infant Development
Universidad de Granada
 2008-04 PHASE2; PHASE3
NCT01392014 COMPLETED
Malaria
Indonesia University
 2008-12 PHASE4
NCT00621634 WITHDRAWN
Tardive Dyskinesia
Université de Montréal
 2008-02 PHASE2
NCT00682578 COMPLETED
Uncomplicated Falciparum Malaria; Vivax Malaria
University of Oxford
 2007-07 PHASE3
NCT00988585 COMPLETED
Heart Disease
Cardiovascular Research Associates
 2009-04 PHASE1
NCT00941785 COMPLETED
Malaria
London School of Hygiene and Tropical Medicine
 2009-07 PHASE2; PHASE3
NCT00393679 COMPLETED
Fever; Malaria
Institute of Tropical Medicine, Belgium
 2007-07 PHASE3
NCT00585390 COMPLETED
Schizophrenia; Fatty Acid Deficiency
University of Cincinnati
 2008-01 PHASE2; PHASE3
NCT00290056 UNKNOWN
Coronary Artery Disease; Arrhythmia
Sheba Medical Center
 2005-11 PHASE4
NCT00749307 COMPLETED
Arrhythmia
Campus Bio-Medico University
 2008-06 PHASE2; PHASE3
NCT00886704 COMPLETED
Atherosclerosis
Ludwig-Maximilians - University of Munich
 2009-04
NCT00691418 WITHDRAWN
Premature Birth
Kaiser Permanente
 2008-07
NCT01061554 COMPLETED
Healthy
Ayanda AS
 2009-03 PHASE1
NCT00634686 UNKNOWN
Osteoporosis; Frailty
Donaghue Medical Research Foundation
 2007-01 PHASE4
NCT00440050 COMPLETED
Alzheimer's Disease
Alzheimer's Disease Cooperative Study (ADCS)
 2007-02 PHASE3
NCT01075932 COMPLETED
Cerebral Blood Flow; Cognitive Function
Northumbria University
 2009-04
NCT00455416 UNKNOWN
Follicular Lymphoma
Oslo University Hospital
 2007-04 PHASE2
NCT00818467 COMPLETED
Vitamin D Status
Creighton University
 2008-05 PHASE4
NCT01075919 COMPLETED
Cognitive Function; Mood
Northumbria University
 2007-12
NCT00620529 COMPLETED
Polycystic Ovary Syndrome
Keogh Institute for Medical Research
 2008-02 PHASE4
NCT00278135 COMPLETED
Age-Related Cognitive Decline; Age-Related Memory Disorders
dsm-firmenich Switzerland AG
 2005-12
NCT00221546 COMPLETED
Cystic Fibrosis
University Hospital, Ghent
 2007-09 PHASE2
NCT00852371 COMPLETED
Malaria; Intermittent Preventive Treatment
London School of Hygiene and Tropical Medicine
 2008-02 PHASE3
NCT00244816 COMPLETED
Metastatic Melanoma
American Regent, Inc.
 2005-10 PHASE2
NCT00014027 COMPLETED
Healthy
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
 2001-04-04 PHASE1
NCT00422877 TERMINATED
Cancer of the Liver
American Regent, Inc.
 2007-01 PHASE2
NCT00333554 COMPLETED
Type 1 Diabetes Mellitus
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
 2006-06
NCT00518414 COMPLETED
Term Infants
Mead Johnson Nutrition
 2007-04
NCT00662142 COMPLETED
Healthy; Attention
University of Cincinnati
 2006-01 PHASE3
NCT00529620 COMPLETED
Malaria
London School of Hygiene and Tropical Medicine
 2007-09 PHASE3
NCT00845533 COMPLETED
Uncomplicated Malaria
University of California, San Francisco
 2007-08 PHASE4
NCT00577447 COMPLETED
Autism
Mayo Clinic
 2005-10
NCT00449917 COMPLETED
Macular Pigment Optical Density
PiLeJe
 2006-09 PHASE4
NCT01174134 COMPLETED
Levels of DHA in the Blood
Mead Johnson Nutrition
 2006-07
NCT00249262 COMPLETED
Metastatic Melanoma
American Regent, Inc.
 2005-10 PHASE2
NCT00610922 COMPLETED
Healthy
University of Milan
 2005-05
NCT00678067 COMPLETED
Hypercholesterolemia
University of Milan
 2005-06
NCT00666120 COMPLETED
Healthy Term Infants Solely Formula Fed
Mead Johnson Nutrition
 2005-06
NCT00402389 COMPLETED
Depression; Depression, Postpartum
University of Arizona
 2004-06 PHASE2
NCT00728338 COMPLETED
Hypertriglyceridemia
USDA, Western Human Nutrition Research Center
 2003-06
NCT00373607 COMPLETED
Malaria
Institute of Tropical Medicine, Belgium
 2003-07 PHASE3
NCT00628017 COMPLETED
Alzheimer's Disease; Mild Cognitive Impairment
Taipei City Psychiatric Center, Taiwan
 2003-01
NCT02219399 COMPLETED
Pregnancy
Colorado State University
 2001-01
NCT01180933 COMPLETED
Perinatal DHA and Folate Status; Neurological Development
Ludwig-Maximilians - University of Munich
 2001-11
NCT00000116 COMPLETED
Retinitis Pigmentosa
Carol Weigel DiFranco
 1996-05 PHASE3
NCT01422317 COMPLETED
Coronary Disease; Myocardial Infarction
Helse Stavanger HF
 1995-09 PHASE3
NCT00060749 COMPLETED
Macular Degeneration
National Eye Institute (NEI)
 2003-05-05 PHASE1
NCT00351624 COMPLETED
Healthy
dsm-firmenich Switzerland AG
 2006-05 PHASE3
NCT00024388 UNKNOWN
Kidney Cancer
Theradex
 2001-04 PHASE2
NCT00024401 UNKNOWN
Colorectal Cancer
Theradex
 2001-05 PHASE2
NCT00753818 COMPLETED
Cognitive Development; Growth
Mead Johnson Nutrition
NCT00024375 UNKNOWN
Pancreatic Cancer
Theradex
 2001-06 PHASE2
NCT00024414 UNKNOWN
Prostate Cancer
Theradex
 2001-04 PHASE2
NCT00226187 COMPLETED
Infant, Low Birth Weight
University of Oslo
 2003-12
NCT00360217 COMPLETED
Hypertriglyceridemia (TG>200<500); Hyperlipidemia; Coronary Artery Disease; Coronary Risk Equivalent; Diabetes
Maine Center for Lipids and Cardiovascular Health
 2006-01
NCT00004827 COMPLETED
Retinitis Pigmentosa
Retina Foundation of the Southwest
 1996-03

(data from https://clinicaltrials.gov, updated on 2026-01-07)

Check the DHA (Dihydroartemisinin) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Dihydroartemisinin suppresses nuclear factor kappa B (NF-κB) activation, thereby inhibiting downstream anti-apoptotic transcriptional signaling and inducing intracellular autophagy and apoptosis. This targeted inhibition of cell survival pathways and modulation of inflammatory signaling provides the functional mechanism underlying its clinical evaluation in conditions such as colorectal cancer, metabolic syndrome, and liver disease.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

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Note: Technical data last updated: Sep 1, 2026.