CAS No. 68-41-7
Batch:
Purity:99.97
Chemical Structure
Check the
D-Cycloserine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (4R)-4-amino-1,2-oxazolidin-3-one | |
|---|---|---|
| CAS Number | 68-41-7 | |
| Molecular Formula |
C3H6N2O2 |
|
| Molecular Weight (MW) | 102.09 | |
| SMILES | C1C(C(=O)NO1)N | |
| InChIKey | DYDCUQKUCUHJBH-UWTATZPHSA-N |
D-Cycloserine is a D-alanine analog that acts as a competitive inhibitor of L-alanine racemase and D-alanyl-D-alanine synthetase. By inhibiting these enzymes, it blocks the conversion of L-alanine to D-alanine and the subsequent incorporation of D-alanine into pentapeptide precursors. This disruption impairs peptidoglycan synthesis during early bacterial cell wall assembly, leading to compromised cell wall integrity and inhibition of bacterial growth. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 20 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.