Cyclopamine (11-Deoxojervine) is a potent, specific Smoothened (SMO) antagonist. It affects Hedgehog and PI3K/AKT signaling pathways by binding to SMO and downregulating GLI transcription factors, effectively inhibiting tumor cell proliferation, migration, and invasion while promoting apoptosis.
Cyclopamine (11-Deoxojervine) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Cyclopamine (11-Deoxojervine) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
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- Cyclopamine (11-Deoxojervine) Mechanism of Action: SMO Inhibition in Cancer Cell Research
- Cyclopamine (11-Deoxojervine) Working Concentration | Cell Culture | Treatment
- Cyclopamine (11-Deoxojervine) Solubility in DMSO
- Cyclopamine (11-Deoxojervine) Stock Solution
- Cyclopamine (11-Deoxojervine) Storage
- Cyclopamine (11-Deoxojervine) Stability
- Cyclopamine (11-Deoxojervine) Combination Database
- Cyclopamine (11-Deoxojervine) Molecular Weight
- Cyclopamine (11-Deoxojervine) SMILES
- Cyclopamine (11-Deoxojervine) CAS Number
- Cyclopamine (11-Deoxojervine) Chemical Structure (2D and 3D)
- Cyclopamine (11-Deoxojervine) MedChemExpress (HY-17024)? Try a better option.
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- Cyclopamine (11-Deoxojervine) SDS｜MSDS