CAS No. 113-92-8
| CAS Number | 113-92-8 | |
|---|---|---|
| Molecular Formula |
C16H19ClN2.C4H4O4 |
|
| Molecular Weight (MW) | 390.86 | |
| SMILES | CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O |
Chlorpheniramine maleate is a potent histamine H1 receptor antagonist that targets the histamine H1 receptor to block endogenous histamine-mediated signaling. By competing with histamine for H1 receptor binding, chlorpheniramine suppresses downstream NF-kB activation and inflammatory mediator release. This inhibition reduces vascular permeability, smooth muscle contraction, and allergic cascade responses, providing effective suppression of hypersensitivity reactions in cellular and physiological models. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
78 mg/mL
(199.55 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 78 mg/mL |
| Ethanol | 78 mg/mL |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Chlorpheniramine Maleate Solubility in DMSO
- Chlorpheniramine Maleate Stock Solution
- Chlorpheniramine Maleate Storage
- Chlorpheniramine Maleate Stability
- Chlorpheniramine Maleate Molecular Weight
- Chlorpheniramine Maleate SMILES
- Chlorpheniramine Maleate Chemical Structure (2D and 3D)
- Chlorpheniramine Maleate SDS｜MSDS