Camptothecin (CPT): Mechanism of Action

Camptothecin (CPT) MOA:Targeting TOP1/DNA Replication Pathway for Nanomedicine and Drug Delivery Systems

🎯 check Camptothecin (CPT) product page

Camptothecin (CPT) is a potent natural DNA topoisomerase I inhibitor. It affects DNA damage response and apoptosis signaling by binding to the Topo I-DNA cleavable complex and preventing DNA re-ligation, inhibiting DNA replication and inducing cancer cell apoptosis.

Primary Applications and Mechanism of Action