CAS No. 957217-65-1

Batch: Purity:99.14
BTZ043 Racemate Chemical Structure
Chemical Structure
Check the BTZ043 Racemate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 957217-65-1
Molecular Formula

C17H16F3N3O5S

Molecular Weight (MW) 431.39
SMILES CC1COC2(O1)CCN(CC2)C3=NC(=O)C4=C(S3)C(=CC(=C4)C(F)(F)F)[N+](=O)[O-]

Ordering Information

Biological Activity

BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor and antimycobacterial agent, exhibiting minimum inhibitory concentrations (MIC) ofagainst M. tuberculosis H37Rv andagainst Mycobacterium smegmatis. By inhibiting DprE1 activity, it blocks the formation of decaprenylphosphoryl arabinose, an essential precursor for cell-wall arabinan synthesis, ultimately causing cell lysis and bacterial death. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 22 mg/mL (50.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.