CAS No. 160003-66-7

Batch: Purity:99.86
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Iniparib (BSI-201) Chemical Structure
Chemical Structure
Check the Iniparib (BSI-201) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-iodo-3-nitrobenzamide
CAS Number 160003-66-7
Molecular Formula

C7H5IN2O3
Molecular Weight (MW) 292.03
SMILES C1=CC(=C(C=C1C(=O)N)[N+](=O)[O-])I
InChIKey MDOJTZQKHMAPBK-UHFFFAOYSA-N

Ordering Information

Biological Activity

Iniparib (BSI-201) is a potent PARP1 inhibitor that exerts anti-neoplastic activity across a broad range of cancer cell types. The compound covalently binds and inhibits PARP1, disrupting poly(ADP-ribose) polymerase-mediated signaling and DNA repair pathways. This target inhibition impairs cellular recovery from DNA damage, ultimately leading to compromised genomic stability, reduced cell viability, and the suppression of tumor cell proliferation in multiple solid tumor models.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 58 mg/mL (198.6 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 28 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.