CAS No. 229975-97-7
Batch:
Purity:99.98
Chemical Structure
Check the
Atazanavir (BMS-232632) Sulfate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate;sulfuric acid | |
|---|---|---|
| CAS Number | 229975-97-7 | |
| Molecular Formula |
C38H52N6O7.H2SO4 |
|
| Molecular Weight (MW) | 802.93 | |
| SMILES | CC(C)(C)C(C(=O)NC(CC1=CC=CC=C1)C(CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)C(C(C)(C)C)NC(=O)OC)O)NC(=O)OC.OS(=O)(=O)O | |
| InChIKey | DQSGVVGOPRWTKI-QVFAWCHISA-N |
Atazanavir sulfate is an HIV protease inhibitor targeting HIV-1 protease. It inhibits viral polyprotein processing in cell culture with an EC50 ranging from 2.6 to 5.3 nM. By blocking the proteolytic cleavage of the viral gag precursor p55, it prevents viral maturation and impairs human immunodeficiency virus replication while displaying minimal host cell cytotoxicity. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(124.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
161 mg/mL
(200.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
160 mg/mL
(199.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
104 mg/mL
(129.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 20 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Atazanavir (BMS-232632) Sulfate Solubility in DMSO
- Atazanavir (BMS-232632) Sulfate Stock Solution
- Atazanavir (BMS-232632) Sulfate Storage
- Atazanavir (BMS-232632) Sulfate Stability
- Atazanavir (BMS-232632) Sulfate Molecular Weight
- Atazanavir (BMS-232632) Sulfate SMILES
- Atazanavir (BMS-232632) Sulfate Chemical Structure (2D and 3D)
- Atazanavir (BMS-232632) Sulfate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.