CAS No. 63968-64-9

Batch: Purity:99.83
Artemisinin Chemical Structure
Chemical Structure
Check the Artemisinin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one
CAS Number 63968-64-9
Molecular Formula

C15H22O5

Molecular Weight (MW) 282.33
SMILES CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C
InChIKey BLUAFEHZUWYNDE-NNWCWBAJSA-N

Ordering Information

Biological Activity

Artemisinin is a natural sesquiterpene endoperoxide that functions as a potent antimalarial agent. Cleavage of its endoperoxide bridge generates reactive oxygen species and free radicals that inhibit parasite target proteins, including the calcium ATPase ortholog PfATP6. In addition to disrupting calcium homeostasis in Plasmodium falciparum, artemisinin exhibits selective cytotoxic and antiproliferative activities against various cancer cell lines. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 57 mg/mL (201.89 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 24 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.