CAS No. 623-05-2
Batch:
Purity:99.74
Chemical Structure
Check the
4-Hydroxybenzyl alcohol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 623-05-2 | |
|---|---|---|
| Molecular Formula |
C7H8O2 |
|
| Molecular Weight (MW) | 124.14 | |
| SMILES | C1=CC(=CC=C1CO)O |
4-Hydroxybenzyl alcohol is a natural phenolic compound derived from Gastrodia elata that exhibits neuroprotective and anti-inflammatory activities. It suppresses neuroinflammatory cascades by attenuating activation of the NF-kB signaling pathway. Downstream, this inhibition reduces the production of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6, as well as inflammatory enzymes including iNOS and COX-2, thereby mitigating microglial activation and oxidative neuronal injury. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
24 mg/mL
(193.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- 4-Hydroxybenzyl alcohol Solubility in DMSO
- 4-Hydroxybenzyl alcohol Stock Solution
- 4-Hydroxybenzyl alcohol Storage
- 4-Hydroxybenzyl alcohol Stability
- 4-Hydroxybenzyl alcohol Molecular Weight
- 4-Hydroxybenzyl alcohol SMILES
- 4-Hydroxybenzyl alcohol Chemical Structure (2D and 3D)
- 4-Hydroxybenzyl alcohol SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.