CAS No. 5351-17-7
Batch:
Purity:99.96
Chemical Structure
Check the
4-Aminobenzohydrazide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-aminobenzohydrazide | |
|---|---|---|
| CAS Number | 5351-17-7 | |
| Molecular Formula |
C7H9N3O |
|
| Molecular Weight (MW) | 151.17 | |
| SMILES | NNC(=O)C1=CC=C(N)C=C1 | |
| InChIKey | WPBZMCGPFHZRHJ-UHFFFAOYSA-N |
4-Aminobenzohydrazide is an inhibitor of myeloperoxidase (MPO). By suppressing MPO enzyme activity, 4-aminobenzohydrazide reduces the production of hypochlorous acid and cellular reactive oxygen species. Inhibition of MPO by 4-aminobenzohydrazide specifically enhances inducible nitric oxide synthase (iNOS) expression and induction in MPO-positive cells, thereby modulating downstream inflammatory cellular responses and oxidative stress pathways. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
30 mg/mL
(198.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.