CAS No. 83-07-8
Batch:
Purity:99.23
Chemical Structure
Check the
4-Aminoantipyrine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-amino-1,5-dimethyl-2-phenylpyrazol-3-one | |
|---|---|---|
| CAS Number | 83-07-8 | |
| Molecular Formula |
C11H13N3O |
|
| Molecular Weight (MW) | 203.24 | |
| SMILES | CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N | |
| InChIKey | RLFWWDJHLFCNIJ-UHFFFAOYSA-N |
4-Aminoantipyrine is a pyrazolone derivative and active metabolite of aminopyrine that exhibits analgesic, anti-inflammatory, and antipyretic activities. It acts as a cyclooxygenase inhibitor, suppressing prostaglandin biosynthesis to alleviate inflammatory responses and pyrexia. Additionally, 4-aminoantipyrine serves as a chromogenic reagent in peroxidase-coupled colorimetric assays for detecting hydrogen peroxide and phenolic compounds in biochemical reactions. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
40 mg/mL
(196.81 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 40 mg/mL |
| Ethanol | 40 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.