CAS No. 5631-70-9
Batch:
Purity:99.99
Chemical Structure
Check the
4',5,7-Trimethoxyflavone
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 5631-70-9 | |
|---|---|---|
| Molecular Formula |
C18H16O5 |
|
| Molecular Weight (MW) | 312.32 | |
| SMILES | COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C=C3OC)OC |
4',5,7-Trimethoxyflavone is a natural flavonoid isolated from Kaempferia parviflora that acts as an inducer of apoptosis. Treatment with 4',5,7-trimethoxyflavone increases the sub-G1 cell population, promotes DNA fragmentation, and elevates the Bax to Bcl-xL ratio. These events lead to downstream activation of caspase-3 and cleavage of poly (ADP-ribose) polymerase, ultimately driving apoptotic cell death in cancer cell models. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
62 mg/mL
(198.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 15 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- 4',5,7-Trimethoxyflavone Clinical Trials
- 4',5,7-Trimethoxyflavone Solubility in DMSO
- 4',5,7-Trimethoxyflavone Stock Solution
- 4',5,7-Trimethoxyflavone Storage
- 4',5,7-Trimethoxyflavone Stability
- 4',5,7-Trimethoxyflavone Molecular Weight
- 4',5,7-Trimethoxyflavone SMILES
- 4',5,7-Trimethoxyflavone Chemical Structure (2D and 3D)
- 4',5,7-Trimethoxyflavone SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.