CAS No. 225110-25-8
Batch:
Purity:99.89
Chemical Structure
Check the
(3R,8S)-Falcarindiol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (3R,8S,9Z)-heptadeca-1,9-dien-4,6-diyne-3,8-diol | |
|---|---|---|
| CAS Number | 225110-25-8 | |
| Molecular Formula |
C17H24O2 |
|
| Molecular Weight (MW) | 260.37 | |
| InChIKey | QWCNQXNAFCBLLV-YWALDVPYSA-N |
(3R,8S)-Falcarindiol is a natural polyacetylene compound that functions as an anti-inflammatory agent. It suppresses lipopolysaccharide-stimulated expression of inducible nitric oxide synthase, tumor necrosis factor alpha, interleukin-6, and interleukin-1 beta. Mechanistically, (3R,8S)-Falcarindiol attenuates the activation of JNK, ERK, STAT1, and STAT3 signaling pathways, leading to inhibited inflammatory mediator production and attenuated downstream immune responses. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
52 mg/mL
(199.71 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMF | 100 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.