CAS No. 626-51-7
Batch:
Purity:99.39
Chemical Structure
Check the
3-Methylglutaric acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 626-51-7 | |
|---|---|---|
| Molecular Formula |
C6H10O4 |
|
| Molecular Weight (MW) | 146.14 | |
| SMILES | CC(CC(O)=O)CC(O)=O |
3-Methylglutaric acid is an organic acid metabolite involved in leucine catabolism and associated with 3-methylglutaconic acidurias. It impairs mitochondrial energy metabolism by inhibiting respiratory chain complexes and key metabolic enzymes. This impairment leads to reduced ATP production, elevated reactive oxygen species generation, and lipid peroxidation in neural tissues, downstream triggering oxidative stress and cellular dysfunction. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
29 mg/mL
(198.43 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 29 mg/mL |
| Ethanol | 29 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- 3-Methylglutaric acid Clinical Trials
- 3-Methylglutaric acid Solubility in DMSO
- 3-Methylglutaric acid Stock Solution
- 3-Methylglutaric acid Storage
- 3-Methylglutaric acid Stability
- 3-Methylglutaric acid Molecular Weight
- 3-Methylglutaric acid SMILES
- 3-Methylglutaric acid Chemical Structure (2D and 3D)
- 3-Methylglutaric acid SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.