🛡️ Hazard Overview
- GHS Class: GHS02; GHS07; GHS08; GHS09
- Signal Word: Danger
- Hazard Statements: H226; H304; H315; H317; H400; H410; H412
🧤 PPE Guidelines
- Gloves: Chemical‑resistant gloves suggested
- Eye Protection: Safety goggles suggested
- Respirator: Dust respirator if dust occurs
❄️ Storage
- Storage Temp: -20°C (-4°F) Keep dry
🚑 Emergency First Aid
- For inhalation, skin, eye or ingestion exposure, please refer to full SDS Section 4.
Product identifier
- Product Name: 3-Carene
- Catalog Number: S5595
- CAS Number: 13466-78-9
- IUPAC Name: Bicyclo[4.1.0]hept-3-ene, 3,7,7-trimethyl-
Relevant identified uses and uses advised against
- Identified uses: For research and development use only; laboratory chemicals; manufacture of substances.
- Uses advised against: Not for pharmaceutical, household, or other unapproved uses.
Details of the supplier
- Company: Selleck Chemicals
- TollFree: +1 877 796-6397
- Tel: +1 832 582-8158
- Fax: +1 832 582-8590
Emergency telephone number
- Emergency phone #: +1 832 582-8158
2.1 GHS classification in accordance with 29 CFR 1910 (OSHA HCS):
Flammable liquids: Category 3. H226
Aspiration hazard: Category 1. H304
Skin irritation: Category 2. H315
Skin sensitization: Category 1. H317
Acute aquatic toxicity: Category 1. H400
Chronic aquatic toxicity: Category 1. H410
Chronic aquatic toxicity: Category 3. H412
2.2 GHS Label elements, including precautionary statements
Hazard Pictogram(s):
Signal Word:
Danger
Hazard statement(s):
H226: Flammable liquid and vapor
H304: May be fatal if swallowed and enters airways
H315: Causes skin irritation
H317: May cause an allergic skin reaction
H400: Very toxic to aquatic life
H410: Very toxic to aquatic life with long lasting effects
H412: Harmful to aquatic life with long lasting effects
Precautionary statement(s):
Prevention:
P210: Keep away from heat, hot surface, sparks, open flames and other ignition sources. No smoking.
P233: Keep container tightly closed.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof electrical/ventilating/lighting equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash hands thoroughly after handling.
P272: Contaminated work clothing should not be allowed out of the workplace.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection/hearing protection.
Response:
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
P302+P352: IF ON SKIN: wash with plenty of water.
P303+P361: IF ON SKIN (or hair): Take off immediately all contaminated clothing.
P321: Specific treatment (see information on this label and safety datasheet)).
P331: Do NOT induce vomiting.
P332+P317: If skin irritation occurs: Get medical help.
P333+P317: If skin irritation or rash occurs: Get medical help.
P353: Rinse skin with water [or shower].
P362+P364: Take off contaminated clothing and wash it before reuse.
P370+P378: In case of fire: Use water spray, dry chemical, carbon dioxide, or appropriate foam to extinguish.
P391: Collect spillage.
Storage:
P403+P235: Store in a well-ventilated place. Keep cool.
P405: Store locked up.
Disposal:
P501: P501 Dispose of contents/ container to an approved waste disposal plant.
2.3 Other hazards
None.
3.1 Substances
Product name: 3-Carene
CAS Number: 13466-78-9
PubChem CID: 26049
Molecular formula: C10H16
Molecular weight: 136.23 g/mol
IUPAC name: 3,7,7-trimethylbicyclo[4.1.0]hept-3-ene
3.2 Mixtures
Not applicable (pure substance).
4.1 Description of first aid measures
Inhalation: INHALATION: move victim to fresh air; call a doctor; administer artificial respiration and oxygen if required.
Skin contact: SKIN: wipe off; wash with soap and water. (USCG, 1999)
Eye contact: EYES: flush with water for at least 15 min.
Ingestion: INGESTION: give large amounts of water and induce vomiting; call a doctor.
4.2 Most important symptoms and effects, both acute and delayed
See Section 11 (Toxicological Information).
4.3 Indication of any immediate medical attention and special treatment needed
Treat symptomatically. Contact a poison control center or physician for severe exposure.
5.1 Extinguishing media
Suitable: Dry chemical, carbon dioxide (CO2), alcohol-resistant foam, water spray.
Unsuitable: High-pressure water jet (may spread fire).
5.2 Specific hazards arising from the substance or mixture
Fire Extinguishing Agents Not to Be Used: Water may be ineffective on fire.
Fire Extinguishing Agents: Foam, dry chemical, carbon dioxide (USCG, 1999)
5.3 Advice for firefighters
Wear self-contained breathing apparatus (SCBA) and full protective clothing.
Fight fire from upwind. Cool containers with water spray until fire is extinguished.
6.1 Personal precautions, protective equipment and emergency procedures
Wear appropriate personal protective equipment (see Section 8).
Avoid breathing dust/vapor. Ensure adequate ventilation.
Evacuate personnel to safe areas. Keep people away from and upwind of spill.
6.2 Environmental precautions
Prevent product from entering drains, waterways, or soil.
Contain spill with inert absorbent material.
6.3 Methods and materials for containment and cleaning up
Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.
LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).
FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)
7.1 Precautions for safe handling
Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material.
LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2024)
Keep away from heat, sparks, and open flames. Use explosion-proof equipment.
7.2 Conditions for safe storage, including any incompatibilities
Store in a cool, dry, well-ventilated area. Keep container tightly closed.
Store away from incompatible materials (see Section 10).
Protect from light and moisture.
Recommended storage (industry convention for research compounds): -20°C for long-term storage; 2-8°C for short-term use and transport.
[Note: This is a general industry recommendation. Always verify exact storage conditions with the supplier Certificate of Analysis (COA).]
Store in original container. Keep upright to prevent leakage.
8.1 Exposure controls
8.1.1 Occupational exposure limits (OEL)
OSHA PEL: Not established.
ACGIH TLV: Not established.
NIOSH REL: Not established.
No occupational exposure limit values are established for this substance.
Use the lowest feasible exposure level (ALARA principle).
8.1.2 Appropriate engineering controls
Use in a well-ventilated area. Chemical fume hood recommended for powder handling.
8.2 Individual protection measures
8.2.1 Eye/face protection
Wear safety glasses with side shields.
8.2.2 Skin protection
Wear protective gloves. Recommended material: Nitrile rubber.
Wear suitable protective clothing (lab coat).
8.2.3 Respiratory protection
Respiratory protection usually not required under normal use with adequate ventilation.
Use N95 respirator for large-scale powder handling.
8.2.4 Thermal hazards
Not applicable.
9.1 Information on basic physical and chemical properties
a) Appearance: Carene is a colorless liquid with a sweet, turpentine-like odor. Floats on water. (USCG, 1999)
b) Odor: No data available
c) Odor threshold: No data available
d) pH: No data available
e) Melting point/freezing point: < 25 °C
f) Initial boiling point and boiling range: 338 °F at 760 mmHg (USCG, 1999)
g) Flash point: No data available
h) Evaporation rate: No data available
i) Flammability (solid, gas): No data available
j) Upper/lower flammability or explosive limits: No data available
k) Vapor pressure: 3.72 [mmHg]
l) Vapor density: No data available
m) Relative density: 0.86 at 68 °F (USCG, 1999) - Less dense than water; will float
n) Water solubility: Insoluble in water; soluble in benzene, pet ether
o) Partition coefficient: n-octanol/water: Log P (n-octanol/water): 2.8
p) Auto-ignition temperature: No data available
q) Decomposition temperature: No data available
r) Viscosity: No data available
s) Explosive properties: No data available
t) Oxidizing properties: No data available
9.2 Other information
Complexity: 186
10.1 Reactivity
No specific reactivity hazards identified under normal handling conditions.
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No hazardous reactions under normal conditions.
10.4 Conditions to avoid
Avoid heat, sparks, open flames, direct sunlight, and moisture.
10.5 Incompatible materials
Strong oxidizing agents, strong acids, strong bases.
10.6 Hazardous decomposition products
Thermal decomposition may produce: Carbon monoxide (CO), Carbon dioxide (CO₂).
See also Section 5 (Fire-fighting measures) for combustion products.
11.1 Information on toxicological effects
Acute toxicity:
No acute toxicity data available.
Skin corrosion/irritation:
Causes skin irritation (H315).
Serious eye damage/eye irritation:
No data available.
Respiratory or skin sensitization:
May cause an allergic skin reaction (H317).
Germ cell mutagenicity:
No data available.
Carcinogenicity:
No data available.
Reproductive toxicity:
No data available.
Specific target organ toxicity (single exposure):
No data available.
Specific target organ toxicity (repeated exposure):
No data available.
Aspiration hazard:
May be fatal if swallowed and enters airways (H304).
11.2 Additional information
No additional toxicological information available.
12.1 Toxicity
No ecotoxicity data available.
12.2 Persistence and degradability
No data available.
12.3 Bioaccumulative potential
Log P (n-octanol/water): 2.8
Low potential for bioaccumulation (Log P < 3).
12.4 Mobility in soil
No data available.
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available.
12.6 Other adverse effects
This substance is classified as hazardous to the aquatic environment.
13.1 Waste treatment methods
Waste Treatment Methods: Waste material must be disposed of in accordance with national and local regulations. Leave chemicals in original containers and do not mix with other waste. Handle uncleaned containers in the same manner as the product itself.
14.1 UN number
Not regulated as dangerous goods (research quantities typically exempt).
14.2 UN proper shipping name
Not subject to transport regulations (small quantities for research use).
14.3 Transport hazard class(es)
Not classified as dangerous goods for transport (research quantities).
DOT label: Flammable Liquid
14.4 Packing group
Not applicable (not regulated as dangerous goods in typical research quantities).
14.5 Environmental hazards
Marine pollutant: Yes (classified as environmentally hazardous per GHS).
14.6 Special precautions for user
Transport in original packaging. Ensure containers are tightly sealed.
For bulk or commercial quantities, consult applicable transport regulations (DOT, IATA, IMDG).
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
US EPA / TSCA: Subject to EPA TSCA regulations
EU ECHA / REACH: REACH Status: Cease
SARA 302 Components:
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components:
This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards:
Acute (short-term) health hazard
Environmental hazard
Fire hazard
Massachusetts Right To Know Components:
This material contains components subject to the Massachusetts Right to Know Act. See Section 2 for hazard classification.
Pennsylvania Right To Know Components:
This material contains components subject to the Pennsylvania Right to Know Act. See Section 2 for hazard classification.
New Jersey Right To Know Components:
This material contains components subject to the New Jersey Right to Know Act. See Section 2 for hazard classification.
California Prop. 65 Components:
This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm.
Other regulatory listings:
- The Australian Inventory of Industrial Chemicals: Chemical: Bicyclo[4.1.0]hept-3-ene, 3,7,7-trimethyl-
- EFSA Legal Basis: Regulation (EC) No 1831/2003 (amended)
- Status Regulation (EC): 2007/442
15.2 Chemical safety assessment
A chemical safety assessment has not been carried out for this substance.
For research-use-only compounds, no CSA is required under REACH Annex I.
Revision Date: 2026/09/09
Further Information: The information provided is believed to be correct but is not exhaustive and should be used only as a guideline based on current knowledge. It does not represent a guarantee of the properties of the product. Selleck Chemicals Corporation and its Affiliates shall not be held liable for any damage resulting from handling or contact with the product.