SMILES:
CC(COCC1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)O)O)O
Chemical Structure
Check the
(2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 128446-35-5 | |
|---|---|---|
| Molecular Formula |
C63H112O42 |
|
| Molecular Weight (MW) | 1541.54 | |
| SMILES | CC(COCC1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)O)O)O |
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(64.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
100 mg/mL
(64.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
100 mg/mL
(64.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Jump to
- (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) Clinical Trials
- (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) Solubility in DMSO
- (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) Stock Solution
- (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) Storage
- (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) Stability
- (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) Molecular Weight
- (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) CAS Number
- (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) Chemical Structure (2D and 3D)
- (2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD) SDS|MSDS
Note: Technical data last updated: Sep 1, 2026.