CAS No. 303-38-8

Batch: Purity:98
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Check the 2,3-Dihydroxybenzoic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2,3-dihydroxybenzoic acid
CAS Number 303-38-8
Molecular Formula

C7H6O4
Molecular Weight (MW) 154.12
SMILES C1=CC(=C(C(=C1)O)O)C(=O)O
InChIKey GLDQAMYCGOIJDV-UHFFFAOYSA-N

Biological Activity

2,3-Dihydroxybenzoic acid is a natural phenolic compound that acts as a potent iron-chelating agent and antioxidant. By binding iron ions, it alters cellular iron homeostasis and inhibits iron-dependent oxidative processes. Furthermore, 2,3-dihydroxybenzoic acid exhibits antimicrobial activity and modulates cellular stress responses, contributing to reduced ROS-mediated cell damage and inhibition of microbial growth. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 30 mg/mL (194.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Graziano JH, et al. J Pharmacol Exp Ther. 1974;190(3):570-5.

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Note: Technical data last updated: Sep 1, 2026.