CAS No. 68-96-2
Batch:
Purity:99.94
Chemical Structure
Check the
17-Hydroxyprogesterone
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 68-96-2 | |
|---|---|---|
| Molecular Formula |
C21H30O3 |
|
| Molecular Weight (MW) | 330.46 |
17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen steroid hormone and a key intermediate in human steroidogenesis. Derived from progesterone, it serves as a precursor in the enzymatic biosynthesis of glucocorticoids, such as cortisol, as well as androgens and estrogens. Through conversion by cytochrome P450 enzymes including 21-hydroxylase, 17-hydroxyprogesterone modulates downstream steroid hormone signalling pathways and regulates endocrine homeostasis. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
66 mg/mL
(199.72 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 66 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- 17-Hydroxyprogesterone Clinical Trials
- 17-Hydroxyprogesterone Solubility in DMSO
- 17-Hydroxyprogesterone Stock Solution
- 17-Hydroxyprogesterone Storage
- 17-Hydroxyprogesterone Stability
- 17-Hydroxyprogesterone Molecular Weight
- 17-Hydroxyprogesterone Chemical Structure (2D and 3D)
- 17-Hydroxyprogesterone SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.