CAS No. 403811-55-2
Batch:
Purity:99.95
Chemical Structure
Check the
10058-F4
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (5E)-5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one | |
|---|---|---|
| CAS Number | 403811-55-2 | |
| Molecular Formula |
C12H11NOS2 |
|
| Molecular Weight (MW) | 249.35 | |
| SMILES | CCC1=CC=C(C=C1)C=C2C(=O)NC(=S)S2 | |
| InChIKey | SVXDHPADAXBMFB-JXMROGBWSA-N |
10058-F4 is a small-molecule c-Myc inhibitor that selectively disrupts the c-Myc-Max heterodimerization complex. By inhibiting c-Myc-Max interaction, 10058-F4 prevents the transactivation of downstream c-Myc target gene expression, thereby halting Myc-driven transcriptional programs. Disruption of this signaling axis induces cell cycle arrest, promotes caspase-3-dependent apoptosis, and modulates autophagy in cellular models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
50 mg/mL
(200.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 1 mg/mL |
| Water | Insoluble |
| DMSO |
50 mg/mL
(200.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 13 mg/mL |
| Water | Insoluble |
| DMSO |
49 mg/mL
(196.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 11 mg/mL |
| Water | Insoluble |
| DMSO |
50 mg/mL
(200.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 11 mg/mL |
| Water | Insoluble |
| DMSO |
50 mg/mL
(200.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 7 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- 10058-F4 Mechanism of Action: c-Myc Inhibition in Leukemia Cell Research
- 10058-F4: Selectivity & Specificity
- 10058-F4 Working Concentration | Cell Culture | Treatment
- 10058-F4 Solubility in DMSO
- 10058-F4 Stock Solution
- 10058-F4 Storage
- 10058-F4 Stability
- 10058-F4 Combination Database
- 10058-F4 Molecular Weight
- 10058-F4 SMILES
- 10058-F4 Chemical Structure (2D and 3D)
- 10058-F4 IC50 for Cell-based and Cell-free Assays
- 10058-F4 MedChemExpress (HY-12702)? Try a better option.
- 10058-F4 Tocris (4406)? Try a better option.
- 10058-F4 Cayman (15929)? Try a better option.
- 10058-F4 Sigma (F3680)? Try a better option.
- 10058-F4 CST (66672)? Try a better option.
- 10058-F4 SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.