CAS No. 106-46-7
Batch:
Purity:98.5
Chemical Structure
Check the
1,4-Dichlorobenzene
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 106-46-7 | |
|---|---|---|
| Molecular Formula |
C6H4Cl2 |
|
| Molecular Weight (MW) | 147.00 | |
| SMILES | C1=CC(=CC=C1Cl)Cl |
1,4-Dichlorobenzene is a chlorinated aromatic hydrocarbon widely used as a disinfectant, pesticide, and deodorant. In preclinical toxicological studies, 1,4-dichlorobenzene exposure induces specific nephrotoxicity in male rodents characterized by the excessive accumulation of alpha 2u-globulin within renal proximal tubule cells. This protein accumulation promotes sustained cellular damage and enhanced tubular epithelial cell proliferation. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
29 mg/mL
(197.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.