Home GPCR & G Protein PKA

PKA Activators

Cat.No. Product Name Information Product Use Citations Product Validations
S7858 Dibutyryl cAMP (db cAMP/Bucladesine) sodium Bucladesine sodium is a cell-permeable PKA activator by mimicing the action of endogenous cAMP. Dibutyryl-cAMP (Bucladesine) is also a phosphodiesterase (PDE) inhibitor.
Int J Mol Sci, 2026, 27(1)501
Exploration (Beijing), 2026, 6(2):70160
Reprod Med Biol, 2026, 25(1):e70024
S7857 8-Bromo-cAMP (8-Br-cAMP) Sodium Salt 8-Bromo-cAMP sodium salt is a cell permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0.05 μM; and a PKA activator.
Nat Commun, 2026, 17(1):5800
Br J Pharmacol, 2026, 183(15):4399-4415
Nat Cell Biol, 2025, NONE
Verified customer review of 8-Bromo-cAMP (8-Br-cAMP) Sodium Salt
E4793 Bucladesine calcium Bucladesine calcium (Dibutyryl-cAMP Calcium Salt, DBcAMP calcium salt) is a cell-permeable analog of cyclic AMP. It serves as a potent activator of protein kinase A (PKA) and mimics the effects of endogenous cAMP. It also inhibits phosphodiesterase (PDE) activity, with the potential to treat congestive heart failure, wound healing, and inflammation.
Regen Ther, 2025, 29:499-505