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Australia
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Austria
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Belgium
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Brazil
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Canada
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China
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Czech Republic
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Denmark
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Finland
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France
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Germany
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Greece
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Hong Kong
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Hungary
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Iceland
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India
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Ireland
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Israel
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Italy
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Japan
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Korea
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Luxembourg
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Malaysia
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Netherlands
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New Zealand
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Norway
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Poland
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Qatar
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Romania
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Saudi Arabia
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Singapore
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Spain
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Sweden
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Switzerland
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Taiwan
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Turkey
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United Kingdom
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United States
PAK Inhibitors
| Cat.No. | Product Name | Information | Product Use Citations | Product Validations |
|---|---|---|---|---|
| S8032 | PRT062607 (P505-15) HCl | PRT062607 (P505-15, BIIB057, PRT-2607) HCl is a novel, highly selective Syk inhibitor with IC50 of 1 nM in cell-free assays, >80-fold selective for Syk than Fgr, PAK5, Lyn, FAK, Pyk2, FLT3, MLK1 and Zap70. |
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| S8444 | Padnarsertib (KPT-9274, ATG-019) | Padnarsertib (KPT 9274) is an orally bioavailable small molecule that is a non-competitive dual inhibitor of PAK4 and NAMPT. It shows an IC50 of ~120 nM for NAMPT in a cell-free enzymatic assay. |
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