New MDM2/MDMX Inhibitors

Catalog No.	Product Name	Information
E6569	MD-4251	MD‑4251 is an orally active PROTAC degrader of MDM2. It potently degrades MDM2 in RS4;11 cells with a DC50 of 0.2 nM and activates p53.
E5849	KT-253	KT-253 (Seldegamadlin) is a potent, selective heterobifunctional MDM2 degrader with a DC50 of 0.4 nM and p53 stabilizer. It also exhibits antitumor activity across p53 wild-type hematologic and solid tumors.
≡ All MDM2/MDMX Inhibitors