New mTOR Inhibitors

Catalog No. Product Name Information
E5815 YB-3-17 YB-3−17 is a dual-target compound that effectively and selectively inhibits mTOR with an IC50 of 0.22 nM, while promoting GSPT1 degradation with an IC50 of 5 nM, leading to substantial tumor growth inhibition both in vitro and in vivo. It also exhibits significant antiproliferative activity in glioblastoma models.
S9736 ME-344 ME-344 is a synthetic metabolite of NV-128, a potent inhibitor of mitochondrial oxidative phosphorylation (OXPHOS) complex I, disrupting ATP generation and oxygen consumption. It also inhibits mTOR by downregulating the AKT/mTOR pathway, exhibiting anticancer activity by inhibiting cell growth and viability in leukemia cell lines with IC50 values of 70–260 nM.
F2584 Phospho-mTOR (Ser 2448) Rabbit mAb mTOR (phospho S2448),Phospho-mTOR (Ser2448),p-mTOR
F2907 Phospho-P70 S6 Kinase β/SRK (Ser 371) Rabbit mAb P70 S6 Kinase beta/SRK (phospho S371)
F2852 Raptor (H22E12) Rabbit mAb
All mTOR Inhibitors