| E6717 |
Monepantel |
Monepantel (AAD1566, NUZ-001) is an antiparasitic agent and orally active mTOR inhibitor that promotes autophagy via the mTOR/p70S6K pathway. It modulates nematode-specific nAChR subunits in nematodes and exhibits the potential to be studied in ALS and ovarian cancer. |
| S9883 |
RMC-5552 |
RMC-5552 is a selective bi-steric inhibitor of mTORC1, with the potential for treating mTORC1-activated tumors. It potently inhibits mTORC1-mediated phosphorylation of pS6K and p4EBP1 with IC50 values of 0.14 nM and 0.48 nM, respectively. |
| F0158 |
Phospho-mTOR (Ser2448) Antibody [H1M6] |
mTOR (phospho S2448),Phospho-mTOR (Ser2448),p-mTOR |