New Histone Acetyltransferase Inhibitors

Catalog No.	Product Name	Information
E6456	PF-07248144(Prifetrastat)	PF‑07248144 (Prifetrastat) is a potent and selective catalytic inhibitor of KAT6A and KAT6B that exhibits durable antitumor activity and the potential to treat metastatic breast cancer.
F0019	Phospho-Histone H2A.X (Ser139) Antibody [E5F13]	gamma H2A.X (phospho S139),gamma H2AX [p Ser139],Histone H2A.X (Ser139),p-Histone H2A.X(Ser 139),phospho-H2A.X (Ser139),phospho-Histone H2A.X (Ser139)
E5885	JG-2016	JG-2016 is a potent and selective inhibitor of HAT1, with an IC50 of 14.8 μM and a binding KD of 22.5 μM for the HAT1:Rbap46 complex. It exhibits anti-proliferative activity with EC50 of 10.4 μM, 29.8 μM, and 1.9 μM in HCC1806, FICC1937, and A549 cells, respectively. JG-2016 significantly suppresses tumor growth in an A549 xenograft model.
E6080	AUR1545	AUR1545 is a potent and selective degrader of KAT2A and KAT2B. It exhibits an anti-proliferative effect and significantly inhibits tumor growth in an NCI-H1048 xenograft model.
≡ All Histone Acetyltransferase Inhibitors