New E1 Activating Inhibitors
| Cat.No. | Product Name | Information |
|---|---|---|
| S8341 | TAK-243 (MLN7243) | TAK-243 (MLN7243) is a potent, mechanism-based small-molecule inhibitor of the ubiquitin activating enzyme (UAE) with an IC50 of 1 ± 0.2 nM in the UBCH10 E2 thioester assay. It has minimal inhibitory activity in a panel of kinase and receptor assays, as well as on human carbonic anhydrase type I and type II. |
| S5841 | DKM 2-93 | DKM 2-93 is a relatively selective lead inhibitor of ubiquitin-like modifier activating enzyme 5 (UBA5). |
| ≡ All E1 Activating Inhibitors | ||
