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New TNF-alpha Inhibitors

Catalog No. Product Name Information
S0248 Hispidol Hispidol is a potent inhibitor of TNF-α–induced monocyte adhesion to colon epithelial cells with an IC50 of 0.50 μM, and effectively suppresses LPS-induced TNF-α gene expression. Its inhibition of TNF-α is linked to reduced AP-1 transcriptional activity, highlighting its potential as a therapeutic candidate for IBD.
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