GPR Modulators

Cat.No.	Product Name	Information
E6738^New	BCFTP	BCFTP is a potent, orally active, selective positive allosteric modulator (PAM) of human MrgprX1 that enhances endogenous ligand signaling to inhibit spinal C-fibre nociceptive transmission, thereby relieving heat hyperalgesia and spontaneous pain in neuropathic models without itch or tolerance.
S2950^New	SBI-553	SBI-553 is a β-arrestin–biased, brain-penetrant positive allosteric modulator (PAM) of the neurotensin receptor 1 (NTSR1/NTR1), with an EC50 of 0.34 μM in cellular assays.
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