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Endothelin Receptor Inhibitors
| Cat.No. | Product Name | Information | Product Use Citations | Product Validations |
|---|---|---|---|---|
| E4771 | Aprocitentan | Aprocitentan (ACT-132577) is a pharmacologically active metabolite of Macitentan. This compound is an orally active dual antagonist of ETA/ETB with IC50 values of 3.4 nM and 987 nM, and pA2 values of 6.7 and 5.5, respectively. |
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