CCR Agonist

Cat.No. Product Name Information Product Use Citations Product Validations
S8324 ZK756326 2HCl ZK756326 is a full agonist of CCR8(Chemokine receptor 8) with an IC50 of 1.8 μM, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1.
Cancer Immunology, Immunotherapy, 2022, 2717-2730
Cancer Immunol Immunother, 2022, 10.1007/s00262-022-03196-3
J Exp Med, 2019, 216(12):2763-2777