| A2537 |
Ravulizumab (Anti-Complement C5) |
Ravulizumab (Anti-Complement C5) is a humanized monoclonal antibody that specifically binds with high affinity to the human complement protein C5. Ravulizumab can be used for the research of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and myasthenia gravis. MW: 145.5 KD. |
Human IgG2SA |
| A2538 |
Eculizumab (Anti-Complement C5) |
Eculizumab (Anti-Complement C5) is a long-acting humanized monoclonal antibody targeting against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research. MW: 145.5 KD. |
Human IgG1 |
| A2539 |
Tesidolumab (Anti-Complement C5) |
Tesidolumab (Anti-Complement C5) is a fully-human IgG1/λ monoclonal antibody targeting against Complement C5. Tesidolumab blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex. MW: 145.5 KD. |
Human IgG1 |
| A2540 |
Anti-Complement C3 |
Anti-Complement C3 (NGM621) is an antibody targeting Complement C3. It binds with high affinity to intact human C3. It is used in the research for treatment of Geographic Atrophy. MW: 145.5 KD. |
Human IgG1 |
| A2541 |
Anti-Clusterin |
Anti-Clusterin (AB-16B5) is a humanized IgG2 antibody targeted against clusterin. It is an inhibitor of the epithelial to mesenchymal transition. Anti-Clusterin (AB-16B5) can be used for cancer research. MW: 145.5 KD. |
Human IgG2SA |
| A2542 |
Tepoditamab (Anti-CLEC12A / CD371) |
Tepoditamab (Anti-CLEC12A / CD371) is a bispecific monoclonal antibody that targets and binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Tepoditamab kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells and can be used in acute myeloid leukaemia (AML) research. MW: 145.5 KD. |
Human IgG1 |
| A2543 |
Tinurilimab (Anti-CEACAM6 / CD66c) |
Tinurilimab (Anti-CEACAM6 / CD66c) is an monoclonal antibody targeting against CEACAM6 and CD66c. CEACAM6 is an immune checkpoint regulator suppressing the activity of effector T-cells against tumors. MW: 145.5 KD. |
Human IgG2SA |
| A2544 |
Tusamitamab (Anti-CEACAM5 / CEA / CD66e) |
Tusamitamab (Anti-CEACAM5 / CEA / CD66e) is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine, which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative). MW: 145.5 KD. |
Human IgG1 |
| A2545 |
Anti-CEACAM1 / CD66a |
Anti-CEACAM1 / CD66a (CM-24) is a humanized monoclonal immunoglobulin G4 (IgG4) antibody targeting CEACAM1 and CD66a, with potential immunomodulating and antineoplastic activities. It blocks the binding of CEACAM1-expressing cancer cells to CEACAM1-expressing immune cells and abrogates CEACAM1-mediated immunosuppression. MW: 145.5 KD. |
Human IgG1 |
| A2051 |
Human IgG1 isotype control |
Human IgG1 isotype control is suitable for use as a non-targeting isotype control in various in vitro and in vivo studies, is the isotype control of human IgG1κ antibody. |
human IGg1, κ |
| A2546 |
Actoxumab (Anti-Cdiff Toxin A) |
Actoxumab ( (Anti-Cdiff Toxin A) is a antitoxin antibody against C. difficile toxin A by neutralizing TcdA. Actoxumab prevents both the damage to the gut wall and the inflammatory response, which are associated with C. difficile. Actoxumab has synergy effect with Bezlotoxumab targeting TcdB. MW: 145.5 KD. |
Human IgG1 |
| A2052 |
Human IgG4 isotype control |
Human IgG4 isotype control is suitable for use as a non-targeting isotype control in various in vitro and in vivo studies, is the isotype control of human IgG4κ antibody. |
human IGg4, κ |
| A2547 |
Anti-CDH6 / K-Cadherin |
Anti-CDH6 / K-Cadherin (DS-6000a) is a humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting against the tumor-associated antigen cadherin-6. MW: 145.5 KD. |
Human IgG1 |
| A2548 |
Anti-CDH3 / P-cadherin |
Anti-CDH3 / P-cadherin (PF-03732010) is a antibody targeting p-cadherin. It binds to and inhibits the activity of p-cadherin which may inhibit tumor cell invasion and proliferation in p-cadherin expressing tumor cells. MW: 145.5 KD. |
Human IgG1 |
| A2549 |
Anti-CD98 |
Anti-CD98 (KHK2898) is an antibody targeting CD98. MW: 145.5 KD. |
Human IgG1 |
| A2550 |
Polatuzumab (Anti-CD79b) |
Polatuzumab (Anti-CD79b) is a monoclonal antibody which targets CD79b that is found on the surface of B cells. Polatuzumab sticks to the CD79b protein and delivers the chemotherapy compound into the cell. MW: 145.5 KD. |
Human IgG1 |
| A2551 |
Milatuzumab (Anti-CD74) |
Milatuzumab (Anti-CD74) is a humanized monoclonal antibody targeting CD74, a integral membrane protein. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death. MW:145.5 KD. |
Human IgG1 |
| A2552 |
Itolizumab (Anti-CD6) |
Itolizumab (Anti-CD6) is a humanized recombinant anti-CD6 monoclonal antibody (MAb) targeting the extracellular SRCR distal domain 1 of CD6. Itolizumab reduces T-cell proliferation and inhibits the production of pro-inflammatory cytokines, such as INF-γ, TNFα and IL-6. Itolizumab can be used in the research of psoriasis, rheumatoid arthritis, COVID-19. MW:145.5 KD. |
Human IgG1 |
| A2553 |
Alemtuzumab (Anti-CD52) |
Alemtuzumab (Anti-CD52) is a humanized monoclonal antibody targeting against CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. MW:145.5 KD. |
Human IgG1 |
| A2554 |
Anti-CD46 |
Anti-CD46 (FOR46) is a human monoclonal antibody targeting against CD46. It specifically targets and binds to a specific conformational epitope on the immune modulatory receptor CD46 expressed on certain tumor cells. MW:145.5 KD. |
Human IgG1 |