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Y2 Selective Antagonists

  • Y2
  • Y5
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S6416 JNJ 31020028 JNJ 31020028 is a novel neuropeptide Y Y2 receptor antagonist which bound with high affinity with human and rat Y2 receptor (pIC50=8.07±0.05 for human Y2 receptor, and pIC50=8.22±0.06 for rat Y2 receptor) and >100-fold selective versus human Y1, Y4, and Y5 receptors. Selective human Y2 receptor, pIC50: 8.07; rat Y2 receptor, pIC50: 8.22