• PAK1
  • PAK3
  • PAK2
  • PAK4
  • PAK5
  • PAK6

PAK5 Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8032 PRT062607 (P505-15) HCl PRT062607 (P505-15, BIIB057, PRT-2607) HCl is a novel, highly selective Syk inhibitor with IC50 of 1 nM in cell-free assays, >80-fold selective for Syk than Fgr, PAK5, Lyn, FAK, Pyk2, FLT3, MLK1 and Zap70. Selective PAK5, IC50: 166 nM
S7094 PF-3758309 PF-03758309 (PF-03758309) is a potent, ATP-competitive, pyrrolopyrazole inhibitor of PAK4 with IC50 of 1.3 nM. PF-3758309 is antiproliferative and induces apoptosis in a HCT116 tumor model. Pan PAK5, Ki: 18.1 nM