CAS No. 1422500-60-4
Batch:
Purity:97.04
Chemical Structure
Check the
Ziresovir
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 1422500-60-4 | |
|---|---|---|
| Molecular Formula |
C22H25N5O3S |
|
| Molecular Weight (MW) | 439.53 |
Biological Activity
Ziresovir is an orally bioavailable small-molecule inhibitor targeting the respiratory syncytial virus (RSV) fusion (F) protein. By binding to the viral F glycoprotein, it prevents structural transitions required for viral envelope fusion with host cell membranes. This inhibition effectively blocks viral entry, viral replication, and syncytium formation in infected target cells, thereby disrupting the viral entry pathway. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
12 mg/mL
(27.3 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.