CAS No. 138982-67-9
Batch:
Purity:99.76
Chemical Structure
Check the
Ziprasidone hydrochloride monohydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 138982-67-9 | |
|---|---|---|
| Molecular Formula |
C21H21ClN4OS.ClH.H2O |
|
| Molecular Weight (MW) | 467.41 |
Ziprasidone hydrochloride monohydrate is an atypical antipsychotic agent and combined serotonin and dopamine receptor antagonist, exhibiting high binding affinity for 5-HT2A, 5-HT1A, and dopamine D2 receptors. By antagonizing D2 and 5-HT2A receptors, it modulates downstream G-protein-coupled receptor signaling pathways, inhibiting dopaminergic signaling and regulating neurotransmitter release in central nervous system models. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
5 mg/mL
(10.69 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Ziprasidone hydrochloride monohydrate Solubility in DMSO
- Ziprasidone hydrochloride monohydrate Stock Solution
- Ziprasidone hydrochloride monohydrate Storage
- Ziprasidone hydrochloride monohydrate Stability
- Ziprasidone hydrochloride monohydrate Molecular Weight
- Ziprasidone hydrochloride monohydrate Chemical Structure (2D and 3D)
- Ziprasidone hydrochloride monohydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.