CAS No. 17924-92-4
Batch:
Purity:99.90
Chemical Structure
Check the
Zearalenone
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (4S,12E)-16,18-dihydroxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dione | |
|---|---|---|
| CAS Number | 17924-92-4 | |
| Molecular Formula |
C18H22O5 |
|
| Molecular Weight (MW) | 318.36 | |
| SMILES | CC1CCCC(=O)CCCC=CC2=C(C(=CC(=C2)O)O)C(=O)O1 | |
| InChIKey | MBMQEIFVQACCCH-QBODLPLBSA-N |
Zearalenone is a non-steroidal estrogenic mycotoxin that functions as a potent agonist of estrogen receptors, binding to both ERα and ERβ. Upon binding, zearalenone alters estrogen receptor signaling pathways, modulating gene transcription associated with reproductive and endocrine function. This estrogenic activity induces transcriptomic changes, promotes cell proliferation in estrogen-responsive tissues, and disrupts normal endocrine homeostasis in model systems. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
64 mg/mL
(201.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 64 mg/mL |
| Water | Insoluble |
| DMSO |
64 mg/mL
(201.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 64 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.