Z-VAD-FMK is a cell-permeant, irreversible pan-caspase inhibitor. It binds to the catalytic site of caspase proteases, blocking caspase-dependent apoptosis, pyroptosis, and related proteolytic signaling pathways. It is widely used to distinguish cell death mechanisms.
Z-VAD-FMK IC50 for Cell-based and Cell-free Assays
Comprehensive lC50 Values for Z-VAD-FMK Across Cell-free Enzyme Inhibitory Profiles and Cell- based Functional Assays.