CAS No. 144217-65-2
Batch:
Purity:99.02
Chemical Structure
Check the
YYA-021
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N'-(4-methylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide | |
|---|---|---|
| CAS Number | 144217-65-2 | |
| Molecular Formula |
C18 H27 N3 O2 |
|
| Molecular Weight (MW) | 317.43 | |
| SMILES | CC1=CC=C(C=C1)NC(=O)C(=O)NC2CC(NC(C2)(C)C)(C)C | |
| InChIKey | AYAGJQPDCPRMNG-UHFFFAOYSA-N |
YYA-021 is a CD4-mimic HIV entry inhibitor that competitively inhibits the interaction between the viral envelope glycoprotein gp120 and the host cell receptor CD4. By targeting gp120, YYA-021 blocks CD4 binding and prevents subsequent viral attachment and entry into host cells, interfering with the early stages of the HIV-1 infection cycle and suppressing CD4-dependent viral replication.[1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| 4-Methylpyridine | 10 mg/mL |
| DMSO |
0.01 mg/mL
(0.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.